DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Esyt2 and pla2g4a

DIOPT Version :9

Sequence 1:	NP_001247287.1	Gene:	Esyt2 / 42929	FlyBaseID:	FBgn0266758	Length:	853	Species:	Drosophila melanogaster
Sequence 2:	NP_001120577.1	Gene:	pla2g4a / 100145731	XenbaseID:	XB-GENE-5838849	Length:	749	Species:	Xenopus tropicalis

Alignment Length:	97	Identity:	28/97 - (28%)
Similarity:	51/97 - (52%)	Gaps:	14/97 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   715 PGEHGLGRMQLSIRYSAQRQKLDVTIHK---IQKIPLRDPSNIPDPYVKLYLLPGRTKESKRKTS 776
            |.:|.:...|.|.|::       ||:.|   :.|....|..:.|||||:||:  ....:|:::|.
Frog     6 PYQHIIVEHQYSHRFT-------VTVIKATNVTKGTFGDMLDTPDPYVELYI--SSAPDSRKRTK 61

  Fly   777 VIKDNCNPVYDASFEYLISIAELRQTELEVTV 808
            ...:|.|||::.:||:::.  ..:...||:|:
Frog    62 HFNNNINPVWNETFEFILD--PNQDNVLEITL 91

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Esyt2	NP_001247287.1	SMP_LBD	154..332	CDD:293652
		C2A_Synaptotagmin-like	348..471	CDD:175990
		C2B_Synaptotagmin-like	500..605	CDD:176015
		C2C_KIAA1228	719..847	CDD:175996	26/93 (28%)
pla2g4a	NP_001120577.1	Phospholipid binding. /evidence=ECO:0000305	1..178		28/97 (29%)
		C2_cPLA2	19..138	CDD:176001	24/84 (29%)
		cPLA2_Grp-IVA	144..730	CDD:132839
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	417..458
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910