Protein Alignment Esyt2 and esyt2

DIOPT Version :10

• Sequence 1: NP_001247287.1
• Gene: Esyt2 / 42929
• FlyBaseID: FBgn0266758
• Length: 853
• Species: Drosophila melanogaster
• Sequence 2: XP_031759913.1
• Gene: esyt2 / 100145291
• XenbaseID: XB-GENE-5932769
• Length: 889
• Species: Xenopus tropicalis
• Alignment Length: 904
• Identity: 301/904 - (33%)
• Similarity: 465/904 - (51%)
• Gaps: 141/904 - (15%)

  Fly    49 GTPPTQTTNGN-------SIVATKSVSDDNSIFSVFYTLGKKVAIVGSIYLVGYMGWSVAWLIAP 106
            |.||:...||.       ::.|.:.......|..:||...|...::..:|::||.|.|.:||:..
 Frog    10 GPPPSPAENGQPGGPPAAAVPAEEQGMISVDIAGLFYQFSKTFVLIFPVYVLGYFGLSFSWLLIA 74

  Fly   107 VILSV--ARDQLAKTSEKKRDIAKASALASEKDVI---LARIDELPAWVYFPDVERCEWLNKILK 166
            ::|.|  .:::..|.|...|.:|   .|.||:..:   :|.|| |||||:|||:||.|||||.:|
 Frog    75 LVLLVWWRKNKGNKNSRLYRALA---FLESEEKSVKHHIASID-LPAWVHFPDIERAEWLNKTVK 135

  Fly   167 QVWPNANHFARTLVKETIEPNVALALANYKMHGFRFDRIILGTIPPRIGGVKIYDKNVDRNEIIM 231
            .:||....|...|.:|||||  |:..||..:..|.|.:|.:|:.|.|:.|||:|.:|||:.:||:
 Frog   136 HMWPYICQFIEKLFRETIEP--AVRGANAHLSTFNFTKIDMGSQPLRVNGVKVYTENVDKRQIIL 198

  Fly   232 DLDLFYASDCDINF----YLGGMKGGIKDFQIHGWVRVVMKPLIRSMPLVGGLQIFFLNNPNIDF 292
            ||.:.:..:.:|:.    |.  .:.|:|..|:||.:|||::|||..:|:||.|.||||..|.::.
 Frog   199 DLQISFVGETEIDLEVKRYF--CRAGVKSIQLHGTMRVVLEPLIGDVPIVGALSIFFLRKPLLEI 261

  Fly   293 NLVGVIDFMDMPGLSDLLRRIIVEQIGNVMVLPNKLPISLSEEVSAVALKMPEPEGILRIHVVEA 357
            |..|:.:.:|||||:.|...||::.|.|.:||||::.:.|..:|....|:.|.|:|:||||.:||
 Frog   262 NWTGLTNMLDMPGLNGLSDTIILDIISNYLVLPNRITVPLVSDVQIAQLRFPIPKGVLRIHFLEA 326

  Fly   358 KDLMKKDISVLG--KGKSDPYAIINVGAQEFKTQIIDNNVNPKWDYWCEACIFTTIGHYIGFSLW 420
            :|||.||..:.|  |||||||.::.:|.|.|::::|..|:||||:...||.:....|..:...|:
 Frog   327 QDLMWKDTYMKGLVKGKSDPYGVVRLGNQVFQSKVIKENLNPKWNEVYEALVHEHPGQELEIELF 391

  Fly   421 DYDQTMPGVQSDDVLGRASIDIASVIKKGVVDSWLTLEDAKHGLLHVRLQWYKLTADPNDLQQIL 485
            |.|     ...||.||...||:..|.|:.|||.|.||::|..|.||::|:|....:...:|.|:|
 Frog   392 DED-----TDKDDFLGSLLIDLVEVEKERVVDEWFTLDEATSGKLHLKLEWLTPKSTTENLDQVL 451

  Fly   486 LETQLLRVTS---MSSAVLSVFIDSAR-------------HLKQARSS----------------- 517
            ...:..:..:   :|:|:|.:::||||             .||:.|:|
 Frog   452 KSIKADKDQANDGLSAALLILYLDSARSLPSIYEGNLGCGFLKERRASGLIFCENTSSLYRSLFA 516

  Fly   518 -----SKPDPYLVCSVNKQKQQTAMIMRDDSPVWEQGFTFLVSNPDNESLNIKIYDQKTGNDIGQ 577
                 |.|:||::.||....|::.:..:...|||||.|||.|.||..:.|.:::.|:...:.:|.
 Frog   517 GKKIGSSPNPYVLFSVGHTVQESKVKYKTAEPVWEQTFTFFVHNPKRQDLEVEVKDENHQSSMGN 581

  Fly   578 YTYTLSTLLKQFNMEVIQQPFQLQKSGPESKLYMSLSLRILKPGEIDKDSDALEQVAALTRSSSV 642
            ....||.:|...:: .:.|.|.|..|||.|.|.|.::||||...:..:..|  ||     .:|.|
 Frog   582 LKIPLSQILASEDL-TLNQRFHLNNSGPNSSLKMKIALRILPVEKPVRSPD--EQ-----HTSQV 638

  Fly   643 KTPDVAAVSPPAFKESQASSKRLSAESPISEEDPVAATKI-------------SPAMSASTSSE- 693
            |.|.:       ||..|..:.::.:.||.....|....|:             :|:.|....:|
 Frog   639 KRPSI-------FKGKQPPTPQMPSPSPAVAHKPPPTPKLDTNKKLENGNKGSTPSASPKRPTEL 696

  Fly   694 -KPISELATSVLTHRFPDSTSSP-----------------------------------GEHGLGR 722
             |..|.|:.|..||    |.|.|                                   |:..||:
 Frog   697 HKSSSSLSGSSFTH----SPSHPSAKEPTPSIASDISLPVATQELRERLRQLQNGTTLGQSPLGQ 757

  Fly   723 MQLSIRYSAQRQKLDVTIHKIQKIPLRDPSNIPDPYVKLYLLPGRTKESKRKTSVIKDNCNPVYD 787
            :||:||:|:||.||.|.:|..:.: :.......||||::||||.:.:..:|||.|.|...|||||
 Frog   758 IQLTIRHSSQRNKLIVVVHSCRNL-IAFSEEGSDPYVRMYLLPDKRRSGRRKTHVYKKTLNPVYD 821

  Fly   788 ASFEYLISIAELRQTELEVTVCTQKGFLSGGSPIIGMLKIPLDDAEITTQTGLNSWFDL 846
            .:||:.:|:.||::..|::.|....||||....::|.|.:.| :||...: |...|:||
 Frog   822 QTFEFSVSLPELQRRTLDIAVKNSGGFLSRDKGLLGKLLLEL-NAEDAVK-GWTLWYDL 878

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Esyt2	NP_001247287.1	SMP_ESyt	156..332	CDD:439226	75/179 (42%)
		C2A_Synaptotagmin-like	348..471	CDD:175990	54/124 (44%)
		C2B_Synaptotagmin-like	500..605	CDD:176015	37/139 (27%)
		C2C_KIAA1228	719..847	CDD:175996	51/128 (40%)
esyt2	XP_031759913.1	SMP_ESyt2	123..301	CDD:439236	76/181 (42%)
		C2A_C2C_Synaptotagmin_like	317..437	CDD:176037	54/124 (44%)
		C2B_Synaptotagmin-like	469..608	CDD:176015	37/139 (27%)
		PTZ00449	<625..>726	CDD:185628	26/118 (22%)
		C2C_KIAA1228	754..879	CDD:175996	51/128 (40%)