Protein Alignment Cftr and NAP5

DIOPT Version :10

• Sequence 1: NP_651269.1
• Gene: Cftr / 42928
• FlyBaseID: FBgn0039207
• Length: 1402
• Species: Drosophila melanogaster
• Sequence 2: NP_177289.1
• Gene: NAP5 / 843474
• AraportID: AT1G71330
• Length: 324
• Species: Arabidopsis thaliana
• Alignment Length: 333
• Identity: 108/333 - (32%)
• Similarity: 166/333 - (49%)
• Gaps: 32/333 - (9%)

  Fly   585 DRKRYQEVTRCCALSTDFQQLPNGDKTLVGERGASLSGGQRARISLARAVYKPAQIYLMDDPLSA 649
            ||:||.:|...|:||.|.:.|..||:|::||||.:|||||:.||.:|||:|:.|.|||.|||.||
plant     2 DRERYDKVIEACSLSKDLEILSFGDQTVIGERGINLSGGQKQRIHIARALYQDADIYLFDDPFSA 66

  Fly   650 VDAHVGRHLFDEVIGPRGRLAQLKATRILVTHQVHFLSEADVIVIVDQGRILRQGTYQELINSDL 714
            ||||.|.|||.|.:  ||.|.....  |.|||||.||..||:.:::..|||.:.|.|.:::.|..
plant    67 VDAHTGSHLFKEAL--RGLLCSKSV--IYVTHQVEFLPSADLTLVMKDGRISQAGKYNDILISGT 127

  Fly   715 DFARLLERPKEEEEGENSRNQTSPLSVNSLESDD----EDIPFIDGVKDGYQQLRKQSSSVHGSK 775
            ||..|:...:|......|.:.:|....::|:.::    :||.|     ||.|:          |:
plant   128 DFRELIGAHQESLAVVGSADASSVSENSALDEENGVVRDDIGF-----DGKQE----------SQ 177

  Fly   776 SLDSTQLDDNVDEDDLA--EAQASGGISPRVWYEYFHA--GSTLLSFSFMVFVMVMSQVVCSSSD 836
            .|.:.:||....:....  |.:|.|.::..|:::|...  |..|:  .|::...::.|::...|:
plant   178 DLKNDKLDSGEPQRQFVQEEERAKGSVALDVYWKYITLAYGGALV--PFILLGQILFQLLQIGSN 240

  Fly   837 FFANIWTQQEHQRSQGEATFSTFECMYIYGALIIAVVIMTTFRGFLFFKICMHASKVLHDRMFAC 901
            ::. .|.....:..|.....||.  |.:|.||.....:....|..|........:..|..:|..|
plant   241 YWM-AWATPISEDVQAPVKLSTL--MVVYVALAFGSSLCILVRATLLVTAGYKTATELFHKMHHC 302

  Fly   902 ILHATMRF 909
            |..:.|.|
plant   303 IFRSPMSF 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cftr	NP_651269.1	MRP_assoc_pro	12..1356	CDD:188098	108/333 (32%)
NAP5	NP_177289.1	MRP_assoc_pro	<1..>310	CDD:188098	107/331 (32%)
		P-loop containing Nucleoside Triphosphate Hydrolases	<1..112	CDD:476819	59/113 (52%)