Protein Alignment CG5789 and ABCC5

DIOPT Version :9

• Sequence 1: NP_001247286.1
• Gene: CG5789 / 42928
• FlyBaseID: FBgn0039207
• Length: 1402
• Species: Drosophila melanogaster
• Sequence 2: NP_171908.1
• Gene: ABCC5 / 839277
• AraportID: AT1G04120
• Length: 1514
• Species: Arabidopsis thaliana
• Alignment Length: 1424
• Identity: 433/1424 - (30%)
• Similarity: 689/1424 - (48%)
• Gaps: 186/1424 - (13%)

  Fly     1 MDSSAKPTRKNPRQHANIISQLIFAWAIPLLYRGSRRGLNTDDLTQCLKEDRSEQLGDRLEDQWF 65
            ::..|...:..|...|.::|.:..:|..|||..||:|.|...|:......||::.....|:..|
plant   218 VEEEAACLKVTPYSTAGLVSLITLSWLDPLLSAGSKRPLELKDIPLLAPRDRAKSSYKVLKSNW- 281

  Fly    66 KELERSHRKKQKPHLRNALFRCFLGPTIINGLICFIYIVIKTLIPAVLAQLLIQFQKTPVAQLRN 130
             :..:|....:.|.|..|:.:.|......|.    ::..:.||:..|...|:..|
plant   282 -KRCKSENPSKPPSLARAIMKSFWKEAACNA----VFAGLNTLVSYVGPYLISYF---------- 331

  Fly   131 IDVNDISISDSLNRTARAIPNYVLSQAVANSSGSPGDALFPKSLDKAGPLEPIQPPVEEVDHNAT 195
                    .|.|.                      |..:||..
plant   332 --------VDYLG----------------------GKEIFPHE---------------------- 344

  Fly   196 AVRSILDQTVEHMWNDMNSLGAVLVLSTLFCCFLLHHVDLRQ-----RLMGARMRIACCSLIYRK 255
                                |.||. ...|...|:..|..||     .::|..:|.|..:::|||
plant   345 --------------------GYVLA-GIFFTSKLIETVTTRQWYMGVDILGMHVRSALTAMVYRK 388

  Fly   256 TLRLSMKTAGQTPAGYLINLLSNDVNRL-DYGFIFMHWIWIMPLQAMLTCYLIWLNIGIPAIVGV 319
            .|:||........:|.::|.::.||.|: ||.: ::|.||::|:|.:|...:::.::||.|:..:
plant   389 GLKLSSIAKQNHTSGEIVNYMAVDVQRIGDYSW-YLHDIWMLPMQIVLALAILYKSVGIAAVATL 452

  Fly   320 VGL---LLKTVPVQTALSKVTSVLRMRIAERTDARVGIMNELVQGIQVIKMYAWEKPFQAVVAEA 381
            |..   :|.|:|    |:||....:.::....|.|:...:|.::.::|:|:.|||..::..:.|.
plant   453 VATIISILVTIP----LAKVQEDYQDKLMTAKDERMRKTSECLRNMRVLKLQAWEDRYRVRLEEM 513

  Fly   382 RRSEIKQIRYASYLRGF----YLSTMVFTERSTLYITLAAAALMGQTITADFVFSAASYYNILQL 442
            |..|...:|.|.|.:.|    :.|:.:|...    :|.|.:..:|..:||..|.||.:.:.|||.
plant   514 REEEYGWLRKALYSQAFVTFIFWSSPIFVAA----VTFATSIFLGTQLTAGGVLSALATFRILQE 574

  Fly   443 VAAIWYPLAVSFGAEALVSLRRIQDFLMLEGREERTQGLTHKRDQEGGDSRAVTIKDINASWDIE 507
            .... :|..||..|:..|||.||..||..|..:|....:..:    |..:.|:.|||....||..
plant   575 PLRN-FPDLVSMMAQTKVSLDRISGFLQEEELQEDATVVIPR----GLSNIAIEIKDGVFCWDPF 634

  Fly   508 KPQKTLQSINLQIEKGQLCAVIGPVGAGKSSILQLLLGELPVIDGGVFIQGDLSYAAQEPWLFTG 572
            ..:.||..|.:::|||...||.|.||:||||.:..:|||:|.|.|.|.|.|...|.:|..|:.:|
plant   635 SSRPTLSGIQMKVEKGMRVAVCGTVGSGKSSFISCILGEIPKISGEVRICGTTGYVSQSAWIQSG 699

  Fly   573 SVRNNILFGEEFDRKRYQEVTRCCALSTDFQQLPNGDKTLVGERGASLSGGQRARISLARAVYKP 637
            ::..|||||...::.:|:.|.:.|:|..|.:...:||:|::||||.:|||||:.|:.||||:|:.
plant   700 NIEENILFGSPMEKTKYKNVIQACSLKKDIELFSHGDQTIIGERGINLSGGQKQRVQLARALYQD 764

  Fly   638 AQIYLMDDPLSAVDAHVGRHLFDEVIGPRGRLAQL-KATRILVTHQVHFLSEADVIVIVDQGRIL 701
            |.|||:|||.||:|||.|..||.:.|     |:.| :.|.:.|||||.||..||:|:::.:|||:
plant   765 ADIYLLDDPFSALDAHTGSDLFRDYI-----LSALAEKTVVFVTHQVEFLPAADLILVLKEGRII 824

  Fly   702 RQGTYQELINSDLDFARL------------LERPKEEEEGENS-------RNQTSPLSVNSLESD 747
            :.|.|.:|:.:..||..|            :..|..|:..||.       .|..|.:..|.:|:.
plant   825 QSGKYDDLLQAGTDFKALVSAHHEAIEAMDIPSPSSEDSDENPIRDSLVLHNPKSDVFENDIETL 889

  Fly   748 DEDIPFIDGVKDGYQQLRKQSSSVHGSKSLDSTQLDDNVDEDDLAEAQASGGISPRVWYEYFHAG 812
            .:::. ..|.....:.::::......|:.....|.::.|          .|.:|.:|:..|..|.
plant   890 AKEVQ-EGGSASDLKAIKEKKKKAKRSRKKQLVQEEERV----------KGKVSMKVYLSYMGAA 943

  Fly   813 STLLSFSFMVFVMVMSQVVCSSSDFFANIWTQQEHQRSQG-EATFSTFECMYIYGALIIAVVIMT 876
            ..    ..::.:::::|.........:|.|....:.:::| |:.......:.:|.||.....:..
plant   944 YK----GALIPLIILAQAAFQFLQIASNWWMAWANPQTEGDESKVDPTLLLIVYTALAFGSSVFI 1004

  Fly   877 TFRGFLFFKICMHASKVLHDRMFACILHATMRFFDTTPSGRILNRFSKDMGAIDELLPRAMMDFI 941
            ..|..|.....:.|::.|...|...:..|.|.|||:||:||||||.|.|...:|..:|..:..|.
plant  1005 FVRAALVATFGLAAAQKLFLNMLRSVFRAPMSFFDSTPAGRILNRVSIDQSVVDLDIPFRLGGFA 1069

  Fly   942 QIALVMFGILIVIGILNPVLVAAMLVVAVVDVLILKLYLRPSQDLKRLEGICRSPVFSHLSASLT 1006
            ...:.:.||:.|:..:...:...::.|||....:.|.|:..|::|.|:..|.:||:......|:.
plant  1070 STTIQLCGIVAVMTNVTWQVFLLVVPVAVACFWMQKYYMASSRELVRIVSIQKSPIIHLFGESIA 1134

  Fly  1007 GLAIIRS-RQLQDVVAKEFDLLQDVHSSVWQLTMAVNTTLGLWLDCVSCIFLTSVTFSFIISSET 1070
            |.|.||. .|.:..:.:...||.......:....|:.     || |:....|:::.|:|.:....
plant  1135 GAATIRGFGQEKRFIKRNLYLLDCFVRPFFCSIAAIE-----WL-CLRMELLSTLVFAFCMVLLV 1193

  Fly  1071 TY-SGNV-----GLAIAQAMILTGMVQYGVRQVAESLQQMTSVERVLQYTELEQE-PALGEK-TP 1127
            :: .|.:     |||:...:.|.|.:...:....:...::.|:||:.||:::..| ||:.|. .|
plant  1194 SFPHGTIDPSMAGLAVTYGLNLNGRLSRWILSFCKLENKIISIERIYQYSQIVGEAPAIIEDFRP 1258

  Fly  1128 PQQWPTRGQVEFRNMSCRYDPNGSPVLRNLNLTIEAGWKVGIVGRTGAGKSSLIGALFRLAHIE- 1191
            |..||..|.:|..::..||..|...||..::.....|.|:|||||||:|||:||.|||||  ||
plant  1259 PSSWPATGTIELVDVKVRYAENLPTVLHGVSCVFPGGKKIGIVGRTGSGKSTLIQALFRL--IEP 1321

  Fly  1192 --GEIFIDGIETGTISLEILRTRISIIPQDPVLFSATIRYNLDPFERYTDAELWSALEDVELRKA 1254
              |:|.||.|:...|.|..||:|:.||||||.||..|||.||||.|.::|.::|.||:..:|...
plant  1322 TAGKITIDNIDISQIGLHDLRSRLGIIPQDPTLFEGTIRANLDPLEEHSDDKIWEALDKSQLGDV 1386

  Fly  1255 IPG----LDYMVTERGGNFSVGQRQLLCLARAILRNNKVLVLDEATANVDPQTDALIQRTIRIKF 1315
            :.|    ||..|.|.|.|:|||||||:.|.||:|:..|:||||||||:||..||.|||:.||.:|
plant  1387 VRGKDLKLDSPVLENGDNWSVGQRQLVSLGRALLKQAKILVLDEATASVDTATDNLIQKIIRTEF 1451

  Fly  1316 KQCTVLTVAHRLHTVMDSDRIIVMDAGVAVEFDVPYLLLK-KSQGHLRQMVE----ATG 1369
            :.|||.|:|||:.||:|||.::|:..|...|||.|..||: ||...|:.:.|    :||
plant  1452 EDCTVCTIAHRIPTVIDSDLVLVLSDGRVAEFDTPARLLEDKSSMFLKLVTEYSSRSTG 1510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5789	NP_001247286.1	CFTR_protein	9..1367	CDD:273530	430/1412 (30%)
		ABC_membrane	214..441	CDD:294371	66/239 (28%)
		ABCC_MRP_domain1	495..699	CDD:213217	90/204 (44%)
		ABC_membrane	863..1088	CDD:294371	60/231 (26%)
		ABCC_MRP_domain2	1135..1350	CDD:213211	113/221 (51%)
ABCC5	NP_171908.1	MRP_assoc_pro	229..1493	CDD:188098	426/1394 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0054
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D138195at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100026
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.720