Protein Alignment CG5789 and ABCC3

DIOPT Version :9

• Sequence 1: NP_001247286.1
• Gene: CG5789 / 42928
• FlyBaseID: FBgn0039207
• Length: 1402
• Species: Drosophila melanogaster
• Sequence 2: NP_187915.1
• Gene: ABCC3 / 820496
• AraportID: AT3G13080
• Length: 1514
• Species: Arabidopsis thaliana
• Alignment Length: 1424
• Identity: 445/1424 - (31%)
• Similarity: 697/1424 - (48%)
• Gaps: 191/1424 - (13%)

  Fly     2 DSSAKPTRKN------PRQHANIISQLIFAWAIPLLYRGSRRGLNTDDLTQCLKEDRSEQLGDRL 60
            |.|.:..:.|      |...|.|:|.|.|:|..||:..|:::.|:.:|:.|....|....|..:
plant   229 DDSVELNKTNGSGEATPYSRAGILSLLTFSWMSPLIDIGNKKTLDLEDVPQLHDTDSVVGLAPK- 292

  Fly    61 EDQWFKEL-------ERSHRKKQKPHLRNALFRCFLGPTIINGLICFIYIVIKTLIPAVLAQLLI 118
                |:.:       |||.....|  |..||:.......::.....|||
plant   293 ----FRSMLESPDGGERSGVTTFK--LIKALYFTAQWEILVTAFFAFIY---------------- 335

  Fly   119 QFQKTPVAQLRNIDVNDISISDSLNRTARAIPNYVLSQAVANSSGSPGDALFPKSLDKAGPLEPI 183
                                         .:.:||                        ||
plant   336 -----------------------------TVASYV------------------------GP---- 343

  Fly   184 QPPVEEVDHNATAVRSILDQTVEHM--WNDMNSLGAVLVLSTLFC-----CFLLHHVDLRQRLMG 241
                           :::|..|:::  ....|..|.|||: |.|.     |....|...|.:.:|
plant   344 ---------------ALIDTFVQYLNGRRQYNHEGYVLVI-TFFAAKIVECLSQRHWFFRLQKVG 392

  Fly   242 ARMRIACCSLIYRKTLRLSMKTAGQTPAGYLINLLSNDVNRLDYGFIFMHWIWIMPLQAMLTCYL 306
            .|||.|..::||.|.|.||.::.....:|.:||.::.|..|:.....:||..|::.||..|..::
plant   393 IRMRSALVAMIYEKGLTLSCQSKQGRTSGEIINFMTVDAERIGNFSWYMHDPWMVLLQVGLALWI 457

  Fly   307 IWLNIGIPAIVGVVGLLLKTVPVQTALSKVTSVLRMRIAERTDARVGIMNELVQGIQVIKMYAWE 371
            ::.|:|:.:|..:|..:: .:.:.....::....:.::.|..|:|:...:|:::.::::|:..||
plant   458 LYRNLGLASIAALVATII-VMLINFPFGRMQERFQEKLMEAKDSRMKSTSEILRNMRILKLQGWE 521

  Fly   372 KPFQAVVAEARRSE---IKQIRYASYLRGFYLSTMVFTERSTL--YITLAAAALMGQTITADFVF 431
            ..|.:.:.:.|:||   :|:..|.|.:..|     ||....||  ..|..|..|:|..:.:..:.
plant   522 MKFLSKIFDLRKSEEGWLKKYVYNSAVISF-----VFWGAPTLVSVSTFGACILLGIPLESGKIL 581

  Fly   432 SAASYYNILQLVAAIW-YPLAVSFGAEALVSLRRIQDFLMLEGREERTQGLTHKRDQEGGDSRAV 495
            ||.:.:.|||  ..|: .|..:|...:..|||.|:..:|.|    :..|....:|..:|....||
plant   582 SALATFRILQ--EPIYNLPDTISMIVQTKVSLDRLASYLCL----DNLQPDIVERLPKGSSDVAV 640

  Fly   496 TIKDINASWDIEKPQKTLQSINLQIEKGQLCAVIGPVGAGKSSILQLLLGELPVIDGGVFIQGDL 560
            .:.:...|||:.....||:.||.::..|...||.|.||:||||:|..||||:|.:.|.:.:.|..
plant   641 EVINSTLSWDVSSSNPTLKDINFKVFPGMKVAVCGTVGSGKSSLLSSLLGEVPKVSGSLKVCGTK 705

  Fly   561 SYAAQEPWLFTGSVRNNILFGEEFDRKRYQEVTRCCALSTDFQQLPNGDKTLVGERGASLSGGQR 625
            :|.||.||:.:|.:.:|||||:..:|:||.:|...|:||.|.:.|..||:|::||||.:|||||:
plant   706 AYVAQSPWIQSGKIEDNILFGKPMERERYDKVLEACSLSKDLEILSFGDQTVIGERGINLSGGQK 770

  Fly   626 ARISLARAVYKPAQIYLMDDPLSAVDAHVGRHLFDEVIGPRGRLAQLKATRILVTHQVHFLSEAD 690
            .||.:|||:|:.|.|||.|||.||||||.|.|||.||:  .|.|.....  |.|||||.||..||
plant   771 QRIQIARALYQDADIYLFDDPFSAVDAHTGSHLFKEVL--LGLLCSKSV--IYVTHQVEFLPAAD 831

  Fly   691 VIVIVDQGRILRQGTYQELINSDLDFARLLERPKE-----EEEGENSRNQTSPLSVNSLESDDED 750
            :|:::..|||.:.|.|.:::||..||..|:...:|     :....||.::.|.|...::.
plant   832 LILVMKDGRISQAGKYNDILNSGTDFMELIGAHQEALAVVDSVDANSVSEKSALGQENVI----- 891

  Fly   751 IPFIDGVKDGYQQLRKQSSSVHGSKSLDSTQLDDNVDEDDLAEAQASGGISPRVWYEYFHA--GS 813
                  |||......|..|....:..|:|.:....:.::   |.:..|.::..|:::|...  |.
plant   892 ------VKDAIAVDEKLESQDLKNDKLESVEPQRQIIQE---EEREKGSVALDVYWKYITLAYGG 947

  Fly   814 TLLSFSFMVFVMVMSQVVCSSSDFFANIWTQQEHQRSQGEATFSTFECMYIYGALIIAVVIMTTF 878
            .|:  .|::...|:.|::...|:::. .|.....:..|.....||.  |.:|.||.....:....
plant   948 ALV--PFILLGQVLFQLLQIGSNYWM-AWATPVSEDVQAPVKLSTL--MIVYVALAFGSSLCILL 1007

  Fly   879 RGFLFFKICMHASKVLHDRMFACILHATMRFFDTTPSGRILNRFSKDMGAIDELLPRAMMDFIQI 943
            |..|........:..|..:|..||..:.|.|||:||||||::|.|.|..|:|..||   ..|..:
plant  1008 RATLLVTAGYKTATELFHKMHHCIFRSPMSFFDSTPSGRIMSRASTDQSAVDLELP---YQFGSV 1069

  Fly   944 ALVMFGILIVIGILNPVLVAAMLV---VAVVDVLILKLYLRPSQDLKRLEGICRSPVFSHLSASL 1005
            |:.:..::.:||:::.|.....||   |....:...:.|:..:::|.||.|:|::|:..|.|.::
plant  1070 AITVIQLIGIIGVMSQVSWLVFLVFIPVVAASIWYQRYYIAAARELSRLVGVCKAPLIQHFSETI 1134

  Fly  1006 TGLAIIRSRQLQDVVAKEFDL------LQDVHSSVWQLTMAVNTTLGLWLDCVSCI-FLTSVTFS 1063
            :|...|||      .::||..      |.|.:|.....|......|...||.:|.: |:.|:.|.
plant  1135 SGATTIRS------FSQEFRFRSDNMRLSDGYSRPKFYTAGAMEWLCFRLDMLSSLTFVFSLVFL 1193

  Fly  1064 FIISSETTYSGNVGLAIAQAMILTGMVQYGVRQVAESLQQMTSVERVLQYTELEQEPAL--GEKT 1126
            ..|.:........|||:...:.|..:..:.:..:.....::.||||:|||..:..||.|  ....
plant  1194 VSIPTGVIDPSLAGLAVTYGLSLNTLQAWLIWTLCNLENKIISVERILQYASVPSEPPLVIESNR 1258

  Fly  1127 PPQQWPTRGQVEFRNMSCRYDPNGSPVLRNLNLTIEAGWKVGIVGRTGAGKSSLIGALFRLAH-I 1190
            |.|.||:||:||.|::..||.|:...|||.:..|.:.|.:.|||||||:|||:||..|||:.. .
plant  1259 PEQSWPSRGEVEIRDLQVRYAPHMPLVLRGITCTFKGGLRTGIVGRTGSGKSTLIQTLFRIVEPS 1323

  Fly  1191 EGEIFIDGIETGTISLEILRTRISIIPQDPVLFSATIRYNLDPFERYTDAELWSALEDV----EL 1251
            .|||.|||:...||.|..||.|:|||||||.:|..|:|.||||.|.|||.::|.||:..    |:
plant  1324 AGEIRIDGVNILTIGLHDLRLRLSIIPQDPTMFEGTMRSNLDPLEEYTDDQIWEALDKCQLGDEV 1388

  Fly  1252 RKAIPGLDYMVTERGGNFSVGQRQLLCLARAILRNNKVLVLDEATANVDPQTDALIQRTIRIKFK 1316
            ||....||..|:|.|.|:|:|||||:||.|.:|:.:|:||||||||:||..||.|||:|:|..|.
plant  1389 RKKEQKLDSSVSENGDNWSMGQRQLVCLGRVLLKRSKILVLDEATASVDTATDNLIQKTLREHFS 1453

  Fly  1317 QCTVLTVAHRLHTVMDSDRIIVMDAGVAVEFDVPYLLLK-KSQGHLRQMVEATGGESEA 1374
            .|||:|:|||:.:|:|||.::::..|:..|:|.|..||: ||....:.:.|.|...|.:
plant  1454 DCTVITIAHRISSVIDSDMVLLLSNGIIEEYDTPVRLLEDKSSSFSKLVAEYTSRSSSS 1512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5789	NP_001247286.1	CFTR_protein	9..1367	CDD:273530	440/1408 (31%)
		ABC_membrane	214..441	CDD:294371	61/236 (26%)
		ABCC_MRP_domain1	495..699	CDD:213217	96/203 (47%)
		ABC_membrane	863..1088	CDD:294371	65/234 (28%)
		ABCC_MRP_domain2	1135..1350	CDD:213211	112/219 (51%)
ABCC3	NP_187915.1	MRP_assoc_pro	115..1499	CDD:188098	442/1409 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0054
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D138195at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100026
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.720