Protein Alignment CG5789 and haf-3

DIOPT Version :9

• Sequence 1: NP_001247286.1
• Gene: CG5789 / 42928
• FlyBaseID: FBgn0039207
• Length: 1402
• Species: Drosophila melanogaster
• Sequence 2: NP_506927.2
• Gene: haf-3 / 180056
• WormBaseID: WBGene00001813
• Length: 666
• Species: Caenorhabditis elegans
• Alignment Length: 557
• Identity: 145/557 - (26%)
• Similarity: 237/557 - (42%)
• Gaps: 100/557 - (17%)

  Fly   862 MYIYGALIIAVVIMTTFRGFLFFKICMHAS--KVLHD---RMFACILHATMRFFDTTPSGRILNR 921
            :::.||:.||..|           .|||.:  .|::|   .:|..:|...|.|||....|.|::|
 Worm   146 VFMLGAIAIAARI-----------YCMHTAGQLVINDLRKSVFNSVLRQDMAFFDKNKVGEIVSR 199

  Fly   922 FSKDMGAIDELLPRAMMDFIQIALVMF---GILI--------VIGILNPVLVAAMLVVAVVDVLI 975
            .|.|...:...:...:.|..:..:..|   |:::        ||.::.||:|....|..
 Worm   200 LSTDALIVGYSVSMNLSDGARALITCFGSGGLMVYTSLAMCKVIFVVVPVIVGTFAVFG------ 258

  Fly   976 LKLYLRPSQDLKRLEGICRSPVFSHLSASLTGLAIIRSRQLQDVVAKEFDLLQDVHSSVWQLTMA 1040
             ||..:.:..::.............||:..|...::..|       ||.....|..:.:||::..
 Worm   259 -KLQRKYTLMMQEAVAGANQVATERLSSVRTVRMLVAER-------KELAAYSDKINEIWQISKK 315

  Fly  1041 VNTTLGLWLDCVSCIFLTSVTFSF----IISSETTYSGNVGLAIAQAMI----LTGMVQYGVRQV 1097
            .....|....          :|.|    .:||...|..|:   |:|.::    |:....|.|..
 Worm   316 EGLAKGFMFG----------SFQFTGYLALSSILFYGSNL---ISQGLLTYGELSSFCLYAVLS- 366

  Fly  1098 AESLQQMTSVERVLQYTELEQEPALGE-------KTPPQQWPTRGQVEFRNM--SCRYD------ 1147
            |.||..|:..     |.||.:  .||.       |....:.|..|.|:..|:  :.|::
 Worm   367 AGSLSAMSGF-----YLELMK--GLGASSRLFELKNREPRIPLEGGVQIGNVKDTIRFEHVAFGY 424

  Fly  1148 PNGSPVLRNLNLTIEAGWKVGIVGRTGAGKSSLIGALFRLAH-IEGEIFIDGIETGTISLEILRT 1211
            .:..|:..|::..:.||....:||.:|:|||::...|.||.. ..|.|.:||.:...|.....|.
 Worm   425 ADRDPLFHNISFDVPAGKITAVVGSSGSGKSTIASLLLRLYDPTSGRILVDGTDLKDIDPSYWRR 489

  Fly  1212 RISIIPQDPVLFSATIRYN-----LDPFERYTDAELWSALEDVELRKAIPGL----DYMVTERGG 1267
            .|..:.|:|||||.||:.|     |:| |..||||:.||.:.....:.|...    |..|.|.|.
 Worm   490 HIGTVGQEPVLFSTTIKENIIYGSLEP-ENVTDAEIVSAADQSNADEFISRFPIKYDTKVGEHGS 553

  Fly  1268 NFSVGQRQLLCLARAILRNNKVLVLDEATANVDPQTDALIQ---RTIRIKFKQCTVLTVAHRLHT 1329
            ..|.||:|.:.:|||::....:|::||||:.:|..::.|::   ..:....|| ||:.:||||.|
 Worm   554 TLSGGQKQRIAIARALVNKPNILIMDEATSALDASSEYLVRIALNKLLANSKQ-TVMIIAHRLST 617

  Fly  1330 VMDSDRIIVMDAGVAVEFDVPYLLLKKSQGHLRQMVE 1366
            :..:|:|:|:|.|...|......|:....|..|::||
 Worm   618 IKHADQIVVVDRGSVAESGSYDELIAIPDGIFRKLVE 654

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5789	NP_001247286.1	CFTR_protein	9..1367	CDD:273530	145/557 (26%)
		ABC_membrane	214..441	CDD:294371
		ABCC_MRP_domain1	495..699	CDD:213217
		ABC_membrane	863..1088	CDD:294371	51/248 (21%)
		ABCC_MRP_domain2	1135..1350	CDD:213211	76/235 (32%)
haf-3	NP_506927.2	MdlB	70..657	CDD:224055	145/557 (26%)
		ABC_membrane	96..366	CDD:279056	53/257 (21%)
		P-loop_NTPase	415..656	CDD:304359	78/242 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000