| Sequence 1: | NP_001247286.1 | Gene: | CG5789 / 42928 | FlyBaseID: | FBgn0039207 | Length: | 1402 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001364202.1 | Gene: | ABCC9 / 10060 | HGNCID: | 60 | Length: | 1549 | Species: | Homo sapiens |
| Alignment Length: | 1403 | Identity: | 424/1403 - (30%) |
|---|---|---|---|
| Similarity: | 676/1403 - (48%) | Gaps: | 193/1403 - (13%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 88 FLGPTIINGLICFIYIVIKTLIPAVLAQLLIQFQKTPVAQLRNIDVNDISISDSLNRTARAIPNY 152
Fly 153 V-LSQAVANSSGSPGD----------ALF-----PKSLDK-----------AGPL--EPIQPPVE 188
Fly 189 EVD---HNATAVRSILDQTVEHMWNDMNSLGAVLVLSTLFCCFLLHHVDLRQRL-----MGARMR 245
Fly 246 IACCSLIYRKTLRLSMK--TAGQTPAGYLINLLSNDVNRLDYGFIFMHWIWIMPLQAMLTCYLIW 308
Fly 309 LNIGIPAIVGVVGLLLKTVPVQTALSKVTSVLRMRIAERTDARVGIMNELVQGIQVIKMYAWEKP 373
Fly 374 FQAVVAEARRSEIKQIRYASYLRGFYLSTMVFTERS-------TLYITLAAAALMGQTITADFVF 431
Fly 432 SAASYYNILQLVAAIWYPLAVSFGAEALVSLRRIQDFLM-----------------LEGREERT- 478
Fly 479 -QGLTHKRDQEG----------------GDSRAVTIKDINASWDIEKPQKTLQSINLQIEKGQLC 526
Fly 527 AVIGPVGAGKSSILQLLLGELPVIDGGVFIQG-----------------DLSYAAQEPWLFTGSV 574
Fly 575 RNNILFGEEFDRKRYQEVTRCCALSTDFQQLPNGDKTLVGERGASLSGGQRARISLARAVYKPAQ 639
Fly 640 IYLMDDPLSAVDAHVGRHLFDEVIGPRGRLAQLKATRILVTHQVHFLSEADVIVIVDQGRILRQG 704
Fly 705 TYQELINSDLD----FARLLERPKEEEEGENSRNQTSPLSVNSLESDDEDIPFIDGVKDGYQQLR 765
Fly 766 KQSSSVHGSKSLDSTQLDDNVDEDDLAEAQASGGISP----------RVWYEYFHAGSTLLSFSF 820
Fly 821 MVFVMVMSQVVCSSSDFFANIWTQQEHQRSQGEATFSTFECMYIYGALII--AVVIMTTFRGFLF 883
Fly 884 FKICMHASKVLHDRMFACILHATMRFFDTTPSGRILNRFSKDMGAIDELLPRAMMDFIQIALVMF 948
Fly 949 GILIVIGILNPVLVAAMLVVAVVDVLILKLYLRPSQDLKRLEGICRSPVFSHLSASLTGLAIIRS 1013
Fly 1014 RQLQDVVAKEFDLLQDVHSSVWQLTMAVNTTLGLWLDCV-SCIFLTSVTFSFIISSETTYSGNVG 1077
Fly 1078 LAIAQAMILTGMVQYGVRQVAESLQQMTSVERVLQYTELEQEPALGEKTP---PQQWPTRGQVEF 1139
Fly 1140 RNMSCRYDPNGSPVLRNLNLTIEAGWKVGIVGRTGAGKSSLIGALFRLAHI-EGEIFIDGIETGT 1203
Fly 1204 ISLEILRTRISIIPQDPVLFSATIRYNLDPFERYTDAELWSALEDVELR---KAIP-GLDYMVTE 1264
Fly 1265 RGGNFSVGQRQLLCLARAILRNNKVLVLDEATANVDPQTDALIQRTIRIKFKQCTVLTVAHRLHT 1329
Fly 1330 VMDSDRIIVMDAGVAVEFDVPYLLLKKSQGHLRQMVEA 1367 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CG5789 | NP_001247286.1 | CFTR_protein | 9..1367 | CDD:273530 | 423/1401 (30%) |
| ABC_membrane | 214..441 | CDD:294371 | 58/240 (24%) | ||
| ABCC_MRP_domain1 | 495..699 | CDD:213217 | 87/220 (40%) | ||
| ABC_membrane | 863..1088 | CDD:294371 | 65/227 (29%) | ||
| ABCC_MRP_domain2 | 1135..1350 | CDD:213211 | 108/219 (49%) | ||
| ABCC9 | NP_001364202.1 | MRP_assoc_pro | 222..1546 | CDD:188098 | 418/1392 (30%) |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 944..967 | 5/28 (18%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0054 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D138195at2759 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 1 | 0.900 | - | - | OOG6_100026 | |
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 4 | 3.720 | |||||