DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG6607 and cep135

DIOPT Version :9

Sequence 1:NP_651266.1 Gene:CG6607 / 42925 FlyBaseID:FBgn0039204 Length:406 Species:Drosophila melanogaster
Sequence 2:XP_005160628.1 Gene:cep135 / 553303 ZFINID:ZDB-GENE-041210-325 Length:1170 Species:Danio rerio


Alignment Length:545 Identity:115/545 - (21%)
Similarity:206/545 - (37%) Gaps:184/545 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 LAMDGTVPEAKYQKLATEYSKLRAQATVLK--KAVLEEQSK--EASLREQLQQYATSLRRTEQEV 66
            |.::.|:     :||..|.:.||||.||||  :.|:|::.|  .|.|.:.:::      .|:|.|
Zfish   616 LDLENTI-----EKLEREKADLRAQVTVLKESRVVVEKELKAQSAVLLQNVEE------ATQQRV 669

  Fly    67 DSLGFR--NKQLESRVSQLQQEISV--------HEQPKKKDKDSG--GRRG--------VQSNSR 111
            :|...|  .:|:|..:|.:|..:||        |:|..|.::...  .|.|        :..|:.
Zfish   670 ESSALRLLQEQMEQSLSDVQHRLSVKTNELQAAHQQIDKLEEKIADLSRHGSSQKDEVVILQNTI 734

  Fly   112 PDADPSLDAAQEA---------LIFEELQKK------------IMENA--QLTSLIDDKQRDLLL 153
            ...|...|..|:|         |:.:|:.:|            .:||:  ||.:::..::|:   
Zfish   735 ASLDREKDTLQDAVDQKTESVVLLQQEVHRKEETLLEVRLTVTDLENSLNQLQAVLSSRERE--- 796

  Fly   154 HTERIASLEQKLEKRIGDQNEL-------------EKRLRKEVETLQHRNSELETKLVDAASMLG 205
                ||||.::|::   .|.||             .:||:.::.|:...|..:..::.:|   |.
Zfish   797 ----IASLRRQLDQ---SQEELFSVSRDREVALRENRRLQDDLATMTRENQAVHAEMQEA---LN 851

  Fly   206 SEDALS----ATGSDTTPLHNL---QQQSNSNQLTSEDRIALLEK-EAAHWRAQFEVAKLHQAFV 262
            ..|.|.    :..|:...:.:|   ::|.|.:         :||: .:.|..::.:..||.|:..
Zfish   852 ERDELKLRVHSYISEVARIESLMAAKEQENRD---------MLERFRSIHTESEDKELKLQQSEG 907

  Fly   263 SNPSKDLSTCSCSTAAAGVTVRPA----------------ESEAKGSQRARDSLQDPPE------ 305
            .|.|..|...|..|....:..|.:                |::.....||...|::..:      
Zfish   908 LNNSIRLELLSSDTERRHLRERVSLQDREIQEHLNALQAYEAQVSSLARAMSRLEEEVQAARAEK 972

  Fly   306 -----------------PPTKEQLIYSVFSKKFE------DLMRLKVQAE---SKLRSYELEVQH 344
                             ..:||..:..:.||..|      :|..::.:.|   .:|.|..|.|::
Zfish   973 ASVLADLASVRELCVKLDSSKELTVRQLTSKSMELERVTGELEDVRSEMELLKKQLGSERLTVRN 1037

  Fly   345 LQNCL------ENATH--------ELKAKDDQLA---------------------SLGGALQMLE 374
            |:..|      |..||        |||...|:||                     .|...:.:|:
Zfish  1038 LETLLSTNRQKEFQTHISASEKESELKVLKDRLALADSKTAGHAREVSQLRGKVSQLQTEMDVLK 1102

  Fly   375 EELTTTRINYEEQISVLTEQVISLS 399
            .:|||.|...|..:..:..|.:|.|
Zfish  1103 RQLTTERFERERAVQEMRRQGLSFS 1127

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6607NP_651266.1 KLRAQ 18..115 CDD:287210 33/120 (28%)
TTKRSYEDQ <233..402 CDD:287216 48/251 (19%)
cep135XP_005160628.1 SMC_prok_B 202..963 CDD:274008 83/379 (22%)
Syntaphilin <291..>407 CDD:291936
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
00.000

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