DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pp1alpha-96A and PPH21

DIOPT Version :9

Sequence 1:	NP_001262919.1	Gene:	Pp1alpha-96A / 42922	FlyBaseID:	FBgn0003134	Length:	327	Species:	Drosophila melanogaster
Sequence 2:	NP_010147.1	Gene:	PPH21 / 851421	SGDID:	S000002292	Length:	369	Species:	Saccharomyces cerevisiae

Alignment Length:	316	Identity:	136/316 - (43%)
Similarity:	195/316 - (61%)	Gaps:	23/316 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SDIMNIDSIISRLLEVRGARPGKNVQLSESEIRSLCLKSREIFLSQPILLELEAPLKICGDIHGQ 66
            ::|..:|..|..|        .|...|||.::..||..:.::...:..:..:..|:.||||:|||
Yeast    65 TNINQLDQWIEHL--------SKCEPLSEDDVARLCKMAVDVLQFEENVKPINVPVTICGDVHGQ 121

  Fly    67 YYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYAENFFLLRGNHECASINRI 131
            ::|||.||:.||..|::||||:|||||||..|:||:..|:|.|::|.....:||||||...|.::
Yeast   122 FHDLLELFKIGGPCPDTNYLFMGDYVDRGYYSVETVSYLVAMKVRYPHRITILRGNHESRQITQV 186

  Fly   132 YGFYDECKRRY-TIKLWKTFTDCFNCLPVAAIVDEKIFCCHGGLSPDLSSMEQIRRIMRPTDVPD 195
            |||||||.|:| :..:||.|||.|:..|:.|:||.||||.||||||.:.:::|:|.:.|..:||.
Yeast   187 YGFYDECLRKYGSANVWKMFTDLFDYFPITALVDNKIFCLHGGLSPMIETIDQVRELNRIQEVPH 251

  Fly   196 QGLLCDLLWSDPDKDTMGWGENDRGVSFTFGAEVVGKFLQKHEFDLICRAHQVVEDGYEFFAKRQ 260
            :|.:||||||||| |..|||.:.||..||||.:|..:|...::..||.||||:|.:||.:..::.
Yeast   252 EGPMCDLLWSDPD-DRGGWGISPRGAGFTFGQDVSEQFNHTNDLSLIARAHQLVMEGYAWSHQQN 315

  Fly   261 LVTLFSAPNYCGEFDNAGAMMSVDDTLMCSFQILKPADKRRFVYPNFGSSGRPLTP 316
            :||:|||||||....|..|:|.||:.           ..|:|:  .:..|.||..|
Yeast   316 VVTIFSAPNYCYRCGNQAAIMEVDEN-----------HNRQFL--QYDPSVRPGEP 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pp1alpha-96A	NP_001262919.1	MPP_PP1_PPKL	6..296	CDD:277359	129/290 (44%)
PPH21	NP_010147.1	MPP_PP2A_PP4_PP6	70..352	CDD:277360	131/303 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53795
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820