Protein Alignment Pp1alpha-96A and PPP1CA

DIOPT Version :9

• Sequence 1: NP_001262919.1
• Gene: Pp1alpha-96A / 42922
• FlyBaseID: FBgn0003134
• Length: 327
• Species: Drosophila melanogaster
• Sequence 2: NP_001008709.1
• Gene: PPP1CA / 5499
• HGNCID: 9281
• Length: 341
• Species: Homo sapiens
• Alignment Length: 340
• Identity: 289/340 - (85%)
• Similarity: 302/340 - (88%)
• Gaps: 16/340 - (4%)

  Fly     2 SDIMNIDSIISRLLE-----------VRGARPGKNVQLSESEIRSLCLKSREIFLSQPILLELEA 55
            |:.:|:||||.||||           |:|:||||||||:|:|||.||||||||||||||||||||
Human     4 SEKLNLDSIIGRLLEGSRVLTPHCAPVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEA 68

  Fly    56 PLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYAENFFLLR 120
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||.|||||||
Human    69 PLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLR 133

  Fly   121 GNHECASINRIYGFYDECKRRYTIKLWKTFTDCFNCLPVAAIVDEKIFCCHGGLSPDLSSMEQIR 185
            ||||||||||||||||||||||.|||||||||||||||:|||||||||||||||||||.||||||
Human   134 GNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIR 198

  Fly   186 RIMRPTDVPDQGLLCDLLWSDPDKDTMGWGENDRGVSFTFGAEVVGKFLQKHEFDLICRAHQVVE 250
            |||||||||||||||||||||||||..||||||||||||||||||.|||.||:.|||||||||||
Human   199 RIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVE 263

  Fly   251 DGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDDTLMCSFQILKPADKRRFVYPNFGS---SGR 312
            ||||||||||||||||||||||||||||||||||:||||||||||||||.:..|..|..   .||
Human   264 DGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGR 328

  Fly   313 PLTPPRGANNKNKKK 327
            |:||||  |:...||
Human   329 PITPPR--NSAKAKK 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pp1alpha-96A	NP_001262919.1	MPP_PP1_PPKL	6..296	CDD:277359	271/300 (90%)
PPP1CA	NP_001008709.1	PTZ00480	6..319	CDD:185658	277/312 (89%)
		MPP_PP1_PPKL	8..309	CDD:277359	271/300 (90%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	395	1.000	Domainoid score	I761
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	602	1.000	Inparanoid score	I952
Isobase	1	0.950	-	0	Normalized mean entropy	S19
OMA	1	1.010	-	-		QHG53795
OrthoDB	1	1.010	-	-		D327461at33208
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	1	1.000	-	-		mtm8649
orthoMCL	1	0.900	-	-		OOG6_100222
Panther	1	1.100	-	-	O	PTHR11668
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X337
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.790