DRSC/TRiP Functional Genomics Resources

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Protein Alignment Pp1alpha-96A and PPEF1

DIOPT Version :9

Sequence 1:NP_001262919.1 Gene:Pp1alpha-96A / 42922 FlyBaseID:FBgn0003134 Length:327 Species:Drosophila melanogaster
Sequence 2:NP_001364915.1 Gene:PPEF1 / 5475 HGNCID:9243 Length:653 Species:Homo sapiens


Alignment Length:322 Identity:92/322 - (28%)
Similarity:149/322 - (46%) Gaps:64/322 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    33 IRSLCLKSREIFLSQPILLELE-APLK---ICGDIHGQYYDLLRLFEYGGFPPESN-YLFLGDYV 92
            :..:..:::::....|....:: :|.|   ||||:||:..||..:|...|.|.|.| |:|.||:|
Human   139 VLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFV 203

  Fly    93 DRGKQSLETICLLLAYKIKYAENFFLLRGNHECASINRIYGFYDECKRRYTI---KLWKTFTDCF 154
            ||||.|:|.:.:|....:.|..:..|.|||||...:|..|||..|...:|.:   ::.:...:.:
Human   204 DRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFY 268

  Fly   155 NCLPVAAIVDEKIFCCHGGLS--PDLSSMEQIRR------IMRPTDV------------------ 193
            ..||:..|||.:|...|||:|  .||:.:.::.|      ::.||:.                  
Human   269 AWLPIGTIVDNEILVIHGGISETTDLNLLHRVERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFN 333

  Fly   194 ----------PDQGL-------LCDLLWSDPDKDTMGWGENDRGVSFTFGAEVVGKFLQKHEFDL 241
                      |.:.|       :.|:|||||......:....||....||.:|..|.|.|::..:
Human   334 AHGRIKTNGSPTEHLTEHEWEQIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKM 398

  Fly   242 ICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDDTLMCS--------FQILK 295
            :.|:|:...:|||.....::||:|||.||..|..|.||.:.     :||        :|:.|
Human   399 LIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIK-----LCSGTTPRFFQYQVTK 455

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Pp1alpha-96ANP_001262919.1 MPP_PP1_PPKL 6..296 CDD:277359 92/322 (29%)
PPEF1NP_001364915.1 IQ 18..37 CDD:197470
MPP_RdgC 115..452 CDD:277364 90/317 (28%)
Catalytic 121..455 91/320 (28%)
EF-hand_7 568..636 CDD:404394
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0639
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000018
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.810

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