DRSC/TRiP Functional Genomics Resources

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Protein Alignment Pp1alpha-96A and PPEF2

DIOPT Version :9

Sequence 1:NP_001262919.1 Gene:Pp1alpha-96A / 42922 FlyBaseID:FBgn0003134 Length:327 Species:Drosophila melanogaster
Sequence 2:NP_006230.2 Gene:PPEF2 / 5470 HGNCID:9244 Length:753 Species:Homo sapiens


Alignment Length:390 Identity:97/390 - (24%)
Similarity:150/390 - (38%) Gaps:129/390 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    27 QLSESEIRSLCLKSREIFLSQPILLELEA----PLKICGDIHGQYYDLLRLFEYGGFP-PESNYL 86
            ||....:.:|..::::..:..|.:..:..    .:.:|||:|||..||:.:|...|.| ||.:|:
Human   140 QLHARYVLNLLYETKKHLVQLPNINRVSTCYSEEITVCGDLHGQLDDLIFIFYKNGLPSPERSYV 204

  Fly    87 FLGDYVDRGKQSLETICLLLAYKIKYAENFFLLRGNHECASINRIYGFYDECKRRYTI---KLWK 148
            |.||:|||||.|:|.:.:|.|:.:.|.:.|.|.|||||...:|..|||..|...:|.:   ::.:
Human   205 FNGDFVDRGKDSVEILMILFAFMLVYPKEFHLNRGNHEDHMVNLRYGFTKEVMNKYKVHGKEILR 269

  Fly   149 TFTDCFNCLPVAAIVDEKIFCCHGGLS--PDLSSMEQIRR------------------------- 186
            |..|.|..||:|.::|||:...|||:|  .||..:::|.|                         
Human   270 TLQDVFCWLPLATLIDEKVLILHGGVSDITDLELLDKIERSKIVSTMRCKTRQKSEKQMEEKRRA 334

  Fly   187 ----------------------------------IMRPTDVPDQGLL------------------ 199
                                              ..|.:.:|..|.|                  
Human   335 NQKSSAQGPIPWFLPESRSLPSSPLRLGSYKAQKTSRSSSIPCSGSLDGRELSRQVRSSVELELE 399

  Fly   200 -C-----------------------------------------DLLWSDPDKDTMGWGENDRGVS 222
             |                                         |:|||||...........||..
Human   400 RCRQQAGLLVTGEKEEPSRSASEADSEAGELRKPTQEEWRQVVDILWSDPMAQEGCKANTIRGGG 464

  Fly   223 FTFGAEVVGKFLQKHEFDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDDTL 287
            ..||.:|..:.|||:....:.|:|:...:||||...|:::|:|||.||.....|.||.:.:...|
Human   465 CYFGPDVTQQLLQKYNMQFLIRSHECKPEGYEFCHNRKVLTIFSASNYYEVGSNRGAYVKLGPAL 529

  Fly   288  287
            Human   530  529

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Pp1alpha-96ANP_001262919.1 MPP_PP1_PPKL 6..296 CDD:277359 97/390 (25%)
PPEF2NP_006230.2 MPP_RdgC 122..537 CDD:277364 97/390 (25%)
Catalytic 128..540 97/390 (25%)
PP2Ac 141..540 CDD:197547 96/389 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 318..382 3/63 (5%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 409..435 0/25 (0%)
EFh 657..722 CDD:238008
EF-hand_7 657..721 CDD:290234
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 732..753
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0639
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000018
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.810

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