DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pp1alpha-96A and gsp-3

DIOPT Version :9

Sequence 1:	NP_001262919.1	Gene:	Pp1alpha-96A / 42922	FlyBaseID:	FBgn0003134	Length:	327	Species:	Drosophila melanogaster
Sequence 2:	NP_491429.1	Gene:	gsp-3 / 172082	WormBaseID:	WBGene00021113	Length:	305	Species:	Caenorhabditis elegans

Alignment Length:	301	Identity:	159/301 - (52%)
Similarity:	225/301 - (74%)	Gaps:	3/301 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSDIMNIDSIISRLLEVRGARPGK-NVQLSESEIRSLCLKSREIFLSQPILLELEAPLKICGDIH 64
            |:..|::|:::||||.| |...|: ...::|.|:::.|..::.:|.||..|||:|.|:.:|||||
Worm     1 MTAPMDVDNLMSRLLNV-GMSGGRLTTSVNEQELQTCCAVAKSVFASQASLLEVEPPIIVCGDIH 64

  Fly    65 GQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYAENFFLLRGNHECASIN 129
            |||.||||:|:..||||:.|:||||||||||:|::|||||:|.:||||.||||:|||||||.:||
Worm    65 GQYSDLLRIFDKNGFPPDVNFLFLGDYVDRGRQNIETICLMLCFKIKYPENFFMLRGNHECPAIN 129

  Fly   130 RIYGFYDECKRRY-TIKLWKTFTDCFNCLPVAAIVDEKIFCCHGGLSPDLSSMEQIRRIMRPTDV 193
            |:||||:||.||| :.:||..|.|.||.:|:..::..:|.|.||||||.|.:::|:|::.||.|.
Worm   130 RVYGFYEECNRRYKSTRLWSIFQDTFNWMPLCGLIGSRILCMHGGLSPHLQTLDQLRQLPRPQDP 194

  Fly   194 PDQGLLCDLLWSDPDKDTMGWGENDRGVSFTFGAEVVGKFLQKHEFDLICRAHQVVEDGYEFFAK 258
            |:..:..||||:|||:...||..|.||||:.||.:||.....:.:.||:.||||||:|||||||.
Worm   195 PNPSIGIDLLWADPDQWVKGWQANTRGVSYVFGQDVVADVCSRLDIDLVARAHQVVQDGYEFFAS 259

  Fly   259 RQLVTLFSAPNYCGEFDNAGAMMSVDDTLMCSFQILKPADK 299
            :::||:||||:|||:|||:.|.|.||:.::|:|.:.||..|
Worm   260 KKMVTIFSAPHYCGQFDNSAATMKVDENMVCTFVMYKPTPK 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pp1alpha-96A	NP_001262919.1	MPP_PP1_PPKL	6..296	CDD:277359	154/291 (53%)
gsp-3	NP_491429.1	MPP_superfamily	6..297	CDD:301300	154/291 (53%)
gsp-3	NP_491429.1	PP2Ac	29..299	CDD:197547	148/269 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53795
OrthoDB	1	1.010	-	-		D327461at33208
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.830