DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pp1alpha-96A and W03D8.2

DIOPT Version :9

Sequence 1:	NP_001262919.1	Gene:	Pp1alpha-96A / 42922	FlyBaseID:	FBgn0003134	Length:	327	Species:	Drosophila melanogaster
Sequence 2:	NP_001249242.1	Gene:	W03D8.2 / 171844	WormBaseID:	WBGene00020985	Length:	364	Species:	Caenorhabditis elegans

Alignment Length:	354	Identity:	143/354 - (40%)
Similarity:	193/354 - (54%)	Gaps:	40/354 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 MNIDSIISRLL------EVRGARPGKN-------VQLSESEIRSLCLKSREIFLSQPILLEL-EA 55
            :|.|:.:..||      ||:..:...|       |.::.|||..|..|.::.||.||.|||: ..
Worm    11 INHDNEVFALLYKILSSEVQTIKGEDNEKVNQLRVDITISEISQLTDKMKKAFLEQPALLEISNE 75

  Fly    56 PLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYAENFFLLR 120
            |:.:..|:|||...|||:|.....||...|||||||||||.||:..:|||...|.:|.::.||||
Worm    76 PITVVADMHGQSIHLLRIFLTNEAPPNQKYLFLGDYVDRGSQSVVVMCLLFCMKHRYPQHVFLLR 140

  Fly   121 GNHECASINRIYGFYDECKRRYT----IKLWKTFTDCFNCLPVAAIVDEKIFCCHGGLSPDLSSM 181
            ||||..:....|||||||..::.    .|:|:.|.|.|||:|:||::..|:||.|||:||.|.|:
Worm   141 GNHEDVNTTLNYGFYDECLEQWKNDEGEKVWRMFIDTFNCMPLAAVIGGKVFCAHGGISPWLESL 205

  Fly   182 EQIRRIMRPTDVPDQGLLCDLLWSDP-DKDTMGWGENDRGVSFTFGAEVVGKFLQKHEFDLICRA 245
            |.|..|.||..||..||.|||||||| ..:..|||.:.||:|||:|..||.:|..|::..|:.|.
Worm   206 EDINSIERPLVVPPYGLACDLLWSDPAQPERNGWGLSHRGISFTYGKSVVEEFCAKNDIALVIRG 270

  Fly   246 HQVVEDGYE-----FFAKRQLVTLFSAPNYCGEFDNA--------GAMMSVDDTLMCSFQILKPA 297
            ||:.::.|.     .|..| |::||||.||.|..:|:        |..:.|...|   ::....|
Worm   271 HQLFKEMYPQGCVLRFGGR-LISLFSALNYEGHKNNSSVLKLEFVGQRVKVKQVL---YRCRHYA 331

  Fly   298 DKRRFVYPNFGSSGRPLTPPRGANNKNKK 326
            ..|...|..|    |.:....|.|.|.||
Worm   332 PLRSNEYLGF----RDMKSSSGKNEKRKK 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pp1alpha-96A	NP_001262919.1	MPP_PP1_PPKL	6..296	CDD:277359	133/321 (41%)
W03D8.2	NP_001249242.1	MPP_superfamily	45..306	CDD:301300	122/261 (47%)
W03D8.2	NP_001249242.1	PP2Ac	47..312	CDD:197547	122/265 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53795
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920