Protein Alignment DZIP1 and DZIP1

DIOPT Version :10

• Sequence 1: NP_651263.1
• Gene: DZIP1 / 42921
• FlyBaseID: FBgn0039201
• Length: 737
• Species: Drosophila melanogaster
• Sequence 2: XP_001238569.4
• Gene: DZIP1 / 4577365
• VectorBaseID: AGAMI1_005973
• Length: 848
• Species: Anopheles gambiae
• Alignment Length: 875
• Identity: 230/875 - (26%)
• Similarity: 377/875 - (43%)
• Gaps: 214/875 - (24%)

  Fly     1 MGFK--GKYPQMVRETGFKLRQYRDGP-LDWRLMGSYETERILREQNFELVDKALTHLSEAPLGT 62
            |.:|  ..:|::.||.||.:|:...|. :|||.:.|.:...|:.|:::|.:|:.:.|:||.|:|.
Mosquito     1 MSYKWHHNFPKIAREAGFTIRELSVGHCIDWRFIASIDPYGIVSEKDYEKLDEFIPHISEVPIGN 65

  Fly    63 VLETHILDSGIAKYFVMSQYAIQYLMCCRTYLDECVTDLKEAHTTAQEEIATLRKSLSESNNEVV 127
            ||...|||..|.||||::|::||||:.|:.:|||.|.:::....|.|:|.|.|.|...:.:.||.
Mosquito    66 VLSNRILDPAIGKYFVLAQFSIQYLLFCKQFLDETVLEIRNTIQTLQDENARLEKMNKKRSEEVT 130

  Fly   128 QLHKRITQIEAIR-----EVVYPCHLCTKNFISNEALNVHIGRKHRVASPPSLTSATGKEKDRDK 187
            ||.:::.:.|.:.     :.:|||..|||||||:|.||.|:.|||  ||....|:....|: :..
Mosquito   131 QLQRKLQRAETMEHHQHAQPIYPCTKCTKNFISSELLNAHMVRKH--ASNVQRTAEPTFER-KPA 192

  Fly   188 ATDVHLINTIKMELEIKQLKERLNAAERNI-------------KERSTGSKRVSPRQEQRHVGIQ 239
            .||.:||||||:|||:|||||||||.|:::             .|.|:.:....|.:....|.||
Mosquito   193 TTDTNLINTIKLELEVKQLKERLNATEKDLHLHRSKHHRCRVCSEDSSSATDRPPAKVLHSVAIQ 257

  Fly   240 SNLAEPKEKDEDSGEARQSEA----------SERKEQLTG------------LAERLSNFEEWQT 282
            |||.:.|:.:::.....|:|.          .:|||:...            |.|:...||.|:|
Mosquito   258 SNLTDDKDSNDEKVAQTQTETMPQSEESATDEQRKERAPAGDFISKSDLQSLLDEQRRLFESWKT 322

  Fly   283 QLKQSNEQFIQDINKRLEGLSHALEQSKQASASTPPLEDRVATPCLEDLE-RILTEKVAEIGKV- 345
            ..:|:..|.|:.:.:.|..:...:|:|::   :||       ||.:.|.. .|..|:..|:.|:
Mosquito   323 GERQTLNQEIETVKRNLVDVIQTIEKSER---NTP-------TPVVVDESGGIWKERYHELEKIY 377

  Fly   346 --SAHRLEEVVYHLEEGYKEKLGALERELKQLSVQKVQPEPVQTVPVASKIPKPVVRKEETNIDR 408
              |..:.:|.:...|:.|.:|:..||:.|::                    .:.:.|||..|
Mosquito   378 ETSQRQAQEAIVSFEKVYTQKVEQLEKLLRE--------------------ARAIERKEIQN--- 419

  Fly   409 IRKQVESEFLKQKHDDDTYSIEEAPRKGSEKPFPQLVT---QVQVVEKEQPSAGSSDSNPTYTKS 470
                          |..|...:    .|:......|.|   ...|:|....:.........|.|.
Mosquito   420 --------------DSSTGHTD----LGTPHSLTHLKTVTLPTVVIESVSVAEDPVQQKEDYVKH 466

  Fly   471 PREPAPNKQETKEATDVSDSLSQEETENEEERSLTEEEGTDVPTSGSEAAREDPTPKT-IKP--- 531
            ..:...::.|..|        |.||.|:....:|...:...|.:|...|..:.|:..| .||
Mosquito   467 NTQTISSESEQAE--------SDEELEDTNVETLKTHQQLAVKSSPLVATSQKPSQVTEAKPHAQ 523

  Fly   532 --SGRIIKSPQKPLTRKDARKMVNRKLMSHGFDMKSKGISHNSLKRVNSELTEHRNKLKLQHPHF 594
              |..::.||:|.:.     .....:|.:.|.|.:||.:...:|......|.:.|:..|.:|.||
Mosquito   524 PSSQALLISPKKQIL-----SQFRARLKAIGVDPRSKQLFGENLNAACKALADRRDVQKQKHGHF 583

  Fly   595 YATRNRIRKFVEKLCSAKFSERAE-------MLLKHKSP----------------LKP------- 629
            :.|||::...||:|..||..:.::       ....|..|                :||
Mosquito   584 FVTRNQLLSRVEQLARAKIGDGSQTKESGQMKTTAHDKPIVMGREKHFPSARGPVIKPRLKTSSA 648

  Fly   630 ME-VPGK---GIP-RSAISEKSEEDIASSQG--------------EEQTDEQ--------TDSSE 667
            || :|.|   .:| ..|:...::.::..|:.              .:.||:.        |..|.
Mosquito   649 MELLPSKQKLHLPDTGAVQHHADMNVFKSKALFTGGSSAPPYRPTIKLTDDDIITVHADVTAMSG 713

  Fly   668 QQ--TRSPSPQRLVS-RDFKARLEEILVKPAATIRGASKS----------------------SLS 707
            ||  |.:|:|.:..| ..:..::|.:|..|..||:.|:|:                      |:|
Mosquito   714 QQELTITPNPSKRASISSYDQQVERLLHTPIKTIQPAAKTPDRVQESTVEETIPSSNHETIDSVS 778

  Fly   708 SRPVPLPRKRVMFNTTEDGKSFNDSDDNLK 737
            :.. |:|:|||:||.        |.:|..|
Mosquito   779 TLK-PIPKKRVLFNL--------DKEDYTK 799

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DZIP1	NP_651263.1	Dzip-like_N	16..133	CDD:433498	46/117 (39%)
		SMC_N	182..>457	CDD:481474	77/316 (24%)
DZIP1	XP_001238569.4	None