Protein Alignment nAChRbeta2 and htr3b

DIOPT Version :9

• Sequence 1: NP_524483.1
• Gene: nAChRbeta2 / 42920
• FlyBaseID: FBgn0004118
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: XP_021324909.1
• Gene: htr3b / 571632
• ZFINID: ZDB-GENE-071012-4
• Length: 369
• Species: Danio rerio
• Alignment Length: 346
• Identity: 108/346 - (31%)
• Similarity: 186/346 - (53%)
• Gaps: 28/346 - (8%)

  Fly    11 LLVPLANSTAPISFEANPD------TKRLYDDLLSNYNRLIRPVVNNTETLTVWLGLKLSQLIEV 69
            ||:.|..|..|:: |..|:      ..:|...||..||..:|||.|.|:..|:::.|.:..:::|
Zfish     5 LLLSLLLSVIPLA-ELVPEKPKRSALNQLTRLLLRKYNCGVRPVQNWTKPTTIYIDLIIQAVLDV 68

  Fly    70 NLKNQVMTTNLWVKQRWFDYKLRWDPEEYGGVEQLYVPSEHIWVPDIVLYNNWD-GNYEVTLMTK 133
            :.:.|.:||::|.:|.|.|..|.|||:|:.|:.::.:.|:.|||||:::....| |...|  :..
Zfish    69 DGQTQKVTTSIWYRQIWNDEFLVWDPDEFDGITEISLSSDAIWVPDLIISEFVDVGKSPV--IPY 131

  Fly   134 ATLKYTGEVFWEPPAIYKSSCEMNVEYFPYDEQICFMKFGSWTYNGAQVDL---KHLDQIPGSNL 195
            ..:..:|:|....|....|:|.:.:..||:|:|.|.:.|.||.::.::|||   :..::|..
Zfish   132 VYVNCSGKVKNYKPIQVVSACHLEIYAFPFDKQNCTLTFRSWLHSVSEVDLALWRPAEEIAN--- 193

  Fly   196 VQVGIDLTEFYLSVEWDILEVPATKNEEYYPDTLE--PFSDITFKLTMRRKTLFYTVNLIVPCVA 258
                 |..||....||::|.||:    .|:...||  .::.|.|.:.:||:.|.|.|.|::|.:.
Zfish   194 -----DTREFMNDGEWELLGVPS----RYWTLNLEDRDYAQIQFNVLIRRRPLLYVVGLLIPSIF 249

  Fly   259 LTFLTVLVFYLPSDSGEKVTLCISILVSLTVFFLLLAEIIPPTSLAVPLLGKYLLFTMILVSLSV 323
            |..:.|:.||||.:||.::|...|||:..||..:.|.:.||.|::..||:|.:....|.|:.||:
Zfish   250 LMVVDVISFYLPPNSGTRITFKTSILLGYTVIRVNLMDEIPATAIKTPLIGVFFAICMALLLLSL 314

  Fly   324 WTTVCVLN-IHFRSPSTHNMS 343
            ..::.|:. :|:.......||
Zfish   315 AMSIFVVKLLHYSEKEVKEMS 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRbeta2	NP_524483.1	LIC	9..479	CDD:273305	108/346 (31%)
		LGIC_ECD_nAChR_proto_alpha-like	29..247	CDD:349832	67/229 (29%)
htr3b	XP_021324909.1	Neur_chan_LBD	26..>325	CDD:332142	98/312 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910