Protein Alignment nAChRbeta2 and ort

DIOPT Version :9

• Sequence 1: NP_524483.1
• Gene: nAChRbeta2 / 42920
• FlyBaseID: FBgn0004118
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Alignment Length: 515
• Identity: 86/515 - (16%)
• Similarity: 177/515 - (34%)
• Gaps: 153/515 - (29%)

  Fly    28 PDTKRLYDDLLSNYNRLIRPVVNNTETLTVWLGLKLSQLIEVNLKNQVMTTNLWVKQRWFDYKLR 92
            |:..:.||.:        ||.....:...|:..:.:..|..::..:.....:::..|.|.|::||
  Fly    34 PEDIKRYDKM--------RPPKKEGQPTIVYFHVTVMGLDSIDENSMTYVADVFFAQTWKDHRLR 90

  Fly    93 --------------------WDPEEY------GGVEQLYVPSEHIWVPDIVLYNNWDGNYEVTLM 131
                                |.|:.:      ...:.:.:|:.::|     ||.    :..:..|
  Fly    91 LPENMTQEYRLLEVDWLKNMWRPDSFFKNAKSVTFQTMTIPNHYMW-----LYK----DKTILYM 146

  Fly   132 TKATLKYTGEVFWEPPAIYKSSCEMNVEYFPYDEQICFMKFGSWTYNGAQVDLKHLDQIPGSNLV 196
            .|.|||.              ||.||...:|:|.|.|.::..|.::....:..:.....|  .:|
  Fly   147 VKLTLKL--------------SCIMNFAIYPHDTQECKLQMESLSHTTDDLIFQWDPTTP--LVV 195

  Fly   197 QVGIDLTEFYL--SVEWDILEVPATKNEEYYPDTLEPFSDITFKLTMRRKTLFYTVNLIVPCVAL 259
            ...|:|.:..|  :...|..:|.:|.|          |:.:....|::|:.::|..|..:|...:
  Fly   196 DENIELPQVALIRNETADCTQVYSTGN----------FTCLEVVFTLKRRLVYYVFNTYIPTCMI 250

  Fly   260 TFLTVLVFYL-PSDSGEKVTLCISILVSLTVFFLLLAEIIPPTSLAVPLLGKYLLFTMILVSLSV 323
            ..::.:.|:: |..:..:|||.::.|::|:.........:||.|. :..:..::....:.|.:::
  Fly   251 VIMSWVSFWIKPEAAPARVTLGVTSLLTLSTQHAKSQSSLPPVSY-LKAVDAFMSVCTVFVFMAL 314

  Fly   324 WTTVCVLNIHFRSPSTHNMSPLVRKLFLHFMPKLMMMRRTQYTLPDYDDSTPSNGYTNEIDVRDS 388
             ...|::||....      :|:.:.  :.:.||                  |..|
  Fly   315 -MEYCLINIVLSD------TPIPKP--MAYPPK------------------PVAG---------- 342

  Fly   389 ISDFPSEFKDSQDGAYDNGMQNSVDSDNVIPRNLTPEVLQALRAVRFIAQHIKDADKDNEIVEDW 453
              |.|   |...:||...|..::..........|..|.::.:..:      ..:..|:..||...
  Fly   343 --DGP---KKEGEGAPPGGSNSTASKQQATMLPLADEKIEKIEKI------FDEMTKNRRIVTTT 396

  Fly   454 KFVSMVLDRFFLWLFTLSCVFGTLAIICQSPSLYDTRSPIDRQLSEIPLRKNNFMLPPDI 513
            :.|                                .|.|:|.....||.:::..:|.|.|
  Fly   397 RRV--------------------------------VRPPLDADGPWIPRQESRIILTPTI 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRbeta2	NP_524483.1	LIC	9..479	CDD:273305	78/479 (16%)
		LGIC_ECD_nAChR_proto_alpha-like	29..247	CDD:349832	43/245 (18%)
ort	NP_524406.1	LIC	31..481	CDD:273305	86/515 (17%)
		Neur_chan_LBD	38..235	CDD:280998	42/239 (18%)
		Neur_chan_memb	243..>334	CDD:280999	16/100 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100