Protein Alignment nAChRbeta2 and CG8916

DIOPT Version :9

• Sequence 1: NP_524483.1
• Gene: nAChRbeta2 / 42920
• FlyBaseID: FBgn0004118
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Alignment Length: 478
• Identity: 91/478 - (19%)
• Similarity: 175/478 - (36%)
• Gaps: 128/478 - (26%)

  Fly    15 LANSTAPISFEANPDTKRLYDDLLSNYNRLIRPVVNNTETLTV-WLGLKLSQLIEVNLKNQVM-- 76
            |:.|::.||.:.....|...|.|..|.:.::..::...|...: ..|..:..:::.|:..:.|
  Fly    82 LSYSSSEISNQRRVRRKAAADMLSRNISMILENLLKRYEQSQLPTHGQGVPTVVQTNILIRSMGP 146

  Fly    77 --------TTNLWVKQRWFDYKLRWDPEEYGGVEQLYVP---SEHIWVPDIVLYNNWDGN-YEVT 129
                    :.:.:.:|.|.|.:|.:.    |.::.|.:.   .:.||.||...||..... :.:|
  Fly   147 VSELDMDYSMDCYFRQYWRDKRLSFK----GPIKSLSLSIKMLDKIWRPDTYFYNGKHSQIHMIT 207

  Fly   130 LMTK-ATLKYTGEVFWEPPAIYKSSCEMNVEYFPYDEQICFMKFGSWTYNGAQV--DLKHLDQ-- 189
            :..| ..|...|.:.:......|::|.|.::.||.|.|.|.:..||:.|...|:  :.|:.|.
  Fly   208 VPNKLLRLDQNGGILYSMRLTIKATCPMELQNFPMDRQSCPLVIGSYGYINQQLIYEWKNQDDAV 272

  Fly   190 --IPGSNLVQVGIDLTEFYLSVEWDILEVP----ATKNEEYYPDTLEPFSDITFKLTMRRKTLFY 248
              :||..|.|             :|::.:.    .|...|      ..||.:.....::|.|.::
  Fly   273 SFVPGMTLNQ-------------FDLISMMHRNFTTVRRE------GDFSVLHVAFNLKRHTGYF 318

  Fly   249 TVNLIVPCVALTFLTVLVFYLPSD-SGEKVTLCISILVSLTVFFLLLAEIIPPTSLAVP----LL 308
            .:.:.|||:.:..|:.:.|::..: :.::|:||::.:::|:...|.....:|....|..    ||
  Fly   319 LIQVYVPCILIVVLSWVSFWIHREATSDRVSLCVTSVLTLSTISLDSRTDLPKVKYATALDWFLL 383

  Fly   309 GKYLLFTMILVSLS------------------VWTTVCVLNIHFRSPSTH----------NMSPL 345
            ..:|.....|:..:                  .|..:|:.|    |.|.|          :..|.
  Fly   384 MSFLYCIATLLEFAGVHYFTKLGSGESPQLEDQWEDICIAN----SLSDHAGEVDGDGEADADPF 444

  Fly   346 VRKLFLHFMPKLMMMRRTQYTLPDYDDSTPSNGYTNEIDVRDSISDFPSEFKDSQDGA------- 403
            .                      |.|.|..|....||....:|:        :|:.|.
  Fly   445 A----------------------DEDSSNGSENDDNEAGASESV--------ESKSGVCVCNKND 479

  Fly   404 -----YDNGMQNSVDSDNVIPRN 421
                 |:..:|||:.....:.||
  Fly   480 ALGLEYEVSLQNSLAGAGFLKRN 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRbeta2	NP_524483.1	LIC	9..479	CDD:273305	91/478 (19%)
		LGIC_ECD_nAChR_proto_alpha-like	29..247	CDD:349832	49/243 (20%)
CG8916	NP_573090.3	LIC	92..598	CDD:273305	87/468 (19%)
		Neur_chan_LBD	111..315	CDD:280998	44/226 (19%)
		Neur_chan_memb	322..>403	CDD:280999	16/80 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100