Protein Alignment nAChRbeta2 and lgc-27

DIOPT Version :9

• Sequence 1: NP_524483.1
• Gene: nAChRbeta2 / 42920
• FlyBaseID: FBgn0004118
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_740977.1
• Gene: lgc-27 / 173802
• WormBaseID: WBGene00022283
• Length: 428
• Species: Caenorhabditis elegans
• Alignment Length: 368
• Identity: 74/368 - (20%)
• Similarity: 138/368 - (37%)
• Gaps: 89/368 - (24%)

  Fly    24 FEANPDTKRLYDDLLSNYNRLIRPVVNNTETLTVWLGLKLSQLIEVNL----KNQV---MTTNLW 81
            ::...|..|:.|.  ||...::.|.|...|||.|       |:::.::    .|:|   |..|.:
 Worm    51 YKLTSDADRMQDK--SNALMMLPPTVAAGETLEV-------QVLDGSITEMWMNEVFKEMNINGF 106

  Fly    82 VKQRWFDYKLRWDPEEYGGVEQLYVPS-EHIWVPDI--------------VLYNNWDGNYEVTLM 131
            :|..|.|.:|||:|||: ..|.|.:.| ..:|.|||              |.|::...||...:.
 Worm   107 LKLSWKDRRLRWNPEEW-KTEVLRLKSMGRLWSPDINSDKLQTGSQSTDFVNYHDIQSNYNGNVT 170

  Fly   132 TKATLKYTGEVFWEPPAIYKSSCEMNVEYFPYDEQICFMKFGSWTYNGAQVDLKHLDQIPGSNLV 196
            .:...:            .|:.|:::...:|.|.:.|.....|..|...   ::.:.:..|::
 Worm   171 ARLEFR------------MKAQCQIDYTEYPNDRKHCCFNLQSNLYKRY---VRFIMEHEGAH-- 218

  Fly   197 QVGIDLTEFYLSVEWDILEVPATKNEEYYPDTLEPFSDITFKLTMR---------------RKTL 246
                           ::|....||...:    ::|......|:...               ||:.
 Worm   219 ---------------EMLNTKNTKTNWH----IDPMYTWISKMNQENDNRAERLEVCVGVVRKSS 264

  Fly   247 FYTVNLIVPCVALTFLTVLVFYLPSDSGEKVTLCISILVSLTVFFLLLAEIIPPTSLA--VPLLG 309
            ...|.|.:| |.::.|.:|:........:::.:.:..|:...:.|..|||..|.....  :|.:.
 Worm   265 TLAVELTLP-VLISALILLLAPFFGKFNQQIYVKMFALLLQFLSFQFLAEKTPQLGFGDNIPKIY 328

  Fly   310 KYLLFTMILVSLSVWTTVCV---LNIHFRSPSTHNMSPLVRKL 349
            .:..||:.:..||:..||.:   ..:..:.|..|..:.|...|
 Worm   329 VFYAFTIGMTVLSLIATVMISAMSRVKRKVPPAHRYTLLASLL 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRbeta2	NP_524483.1	LIC	9..479	CDD:273305	74/368 (20%)
		LGIC_ECD_nAChR_proto_alpha-like	29..247	CDD:349832	51/254 (20%)
lgc-27	NP_740977.1	LGIC_ECD	79..248	CDD:355788	41/212 (19%)
		Cys-loop	181..195	CDD:349787	3/13 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910