Protein Alignment nAChRbeta2 and LOC101732933

DIOPT Version :9

• Sequence 1: NP_524483.1
• Gene: nAChRbeta2 / 42920
• FlyBaseID: FBgn0004118
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: XP_031754974.1
• Gene: LOC101732933 / 101732933
• -ID: -
• Length: 498
• Species: Xenopus tropicalis
• Alignment Length: 509
• Identity: 219/509 - (43%)
• Similarity: 317/509 - (62%)
• Gaps: 52/509 - (10%)

  Fly     3 HWSLLCVFLLVPLANSTAPISFEANPDTKRLYDDLLSNYNRLIRPVVNNTETLTVWLGLKLSQLI 67
            |...:|.|||...|      .|..:....|||:|||.:||..||||:|.::.:.:...:.:|||:
 Frog    16 HGLFICFFLLFLSA------GFFCSNVEHRLYEDLLKSYNPYIRPVMNVSDPVILHFEVSMSQLV 74

  Fly    68 EVNLKNQVMTTNLWVKQRWFDYKLRWDPEEYGGVEQLYVPSEHIWVPDIVLYNNWDGNYEVTLMT 132
            :|:..||:|.||||::..|.||||:|:|.:|||:|.|.:|:..||.||||||||..|.:.|....
 Frog    75 KVDEVNQIMETNLWLRHLWNDYKLKWNPSDYGGIEFLRIPASQIWRPDIVLYNNAVGAFHVDDKA 139

  Fly   133 KATLKYTGEVFWEPPAIYKSSCEMNVEYFPYDEQICFMKFGSWTYNGAQVDLKHLDQIPGSNLVQ 197
            ||.::|:|:|.|.||||:||||:::|.:||:|.|.|.:|||||||:.|::           |||.
 Frog   140 KAVVRYSGDVTWIPPAIFKSSCKIDVTFFPFDYQNCSLKFGSWTYDKAKI-----------NLVM 193

  Fly   198 VG--IDLTEFYLSVEWDILEVPATKNEEYYPDTLEPFSDITFKLTMRRKTLFYTVNLIVPCVALT 260
            :|  |:|.||:.|.||.|:..|..|:|..|...:|.:.|||:.|.:||..||||:.:|:||:.::
 Frog   194 IGSKINLKEFWESGEWVIINAPGYKHEIKYNCCVEIYQDITYSLYIRRLPLFYTIYIIIPCLLIS 258

  Fly   261 FLTVLVFYLPSDSGEKVTLCISILVSLTVFFLLLAEIIPPTSLAVPLLGKYLLFTMILVSLSVWT 325
            .||:||||||||.|||||||:|:|:|||||.|::.||||.|||.:||:|:|||||||.|:||:..
 Frog   259 CLTILVFYLPSDCGEKVTLCMSVLLSLTVFLLVITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVI 323

  Fly   326 TVCVLNIHFRSPSTHNMSPLVRKLFLHFMPKLMMMRRTQ---YTLPD------------------ 369
            ||.|||:|:|:|.||.|...|::.|||.:||:|.|.|.:   |.|..
 Frog   324 TVFVLNVHYRTPKTHTMPHWVKRFFLHLLPKVMFMTRPEKQPYALKPQAYLDISSSEIRSCQDQL 388

  Fly   370 -YDDSTPSNGYTNEIDVRDSISDFPSEFKDSQDGAYDNGMQNSVDSDNVIPRNLTPEVLQALRAV 433
             |.||:.:.|....:...|:..:...  ..|.:..|:.|:.:.        ..|:||:.:|:..|
 Frog   389 FYQDSSCACGQLKRLYTSDTACNVTR--GSSLESMYNLGLHSG--------SGLSPEIREAIEDV 443

  Fly   434 RFIAQHIKDADKDNEIVEDWKFVSMVLDRFFLWLFTLSCVFGTLAIICQSPSLY 487
            .|||:::|..|:..|:.:|||:|:||:||.|||:|.|.|:.||..:..| |.|:
 Frog   444 HFIAENMKAQDEAKEVQDDWKYVAMVIDRIFLWVFVLVCILGTAGLFLQ-PLLF 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRbeta2	NP_524483.1	LIC	9..479	CDD:273305	214/493 (43%)
		LGIC_ECD_nAChR_proto_alpha-like	29..247	CDD:349832	100/219 (46%)
LOC101732933	XP_031754974.1	LIC	34..491	CDD:273305	209/477 (44%)
		LGIC_ECD_nAChR_A3	37..243	CDD:349817	100/216 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	252	1.000	Domainoid score	I2037
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	477	1.000	Inparanoid score	I1443
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D188416at33208
OrthoFinder	1	1.000	-	-		FOG0000583
OrthoInspector	1	1.000	-	-		mtm14085
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X294
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.060