Protein Alignment nAChRalpha2 and ort

DIOPT Version :9

• Sequence 1: NP_524482.1
• Gene: nAChRalpha2 / 42919
• FlyBaseID: FBgn0000039
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Alignment Length: 360
• Identity: 69/360 - (19%)
• Similarity: 146/360 - (40%)
• Gaps: 53/360 - (14%)

  Fly    28 LLLVLLLLCETVQANPDAKR-------LYDDLLSNYNRLIRPVSNNTDTVLVKLGLRLSQLIDLN 85
            ::||:..:|....|..:.::       |.:| :..|::: ||........:|...:.:..|..::
  Fly     6 IILVICTICMKHYAKGEFQQSLAITDILPED-IKRYDKM-RPPKKEGQPTIVYFHVTVMGLDSID 68

  Fly    86 LKDQILTTNVWLEHEWQDHKFKWDPSEYGGVTELYVPSE-----HIWLPDIVLYNNADGEYVVTT 145
            ........:|:....|:||:.:...:    :|:.|...|     ::|.|| ..:.||..   ||.
  Fly    69 ENSMTYVADVFFAQTWKDHRLRLPEN----MTQEYRLLEVDWLKNMWRPD-SFFKNAKS---VTF 125

  Fly   146 MTKAI------LHYTGKVVWTPPAIFKSSCEIDVRYFPFDQQTCFMKFGSWTYDGDQIDLKHISQ 204
            .|..|      |:....:::......|.||.::...:|.|.|.|.::..|.::..|.:..:.
  Fly   126 QTMTIPNHYMWLYKDKTILYMVKLTLKLSCIMNFAIYPHDTQECKLQMESLSHTTDDLIFQW--- 187

  Fly   205 KNDKDNKVEIGIDLREYYPSVEWDILGVPAERHEKY----YPCCAEPYPDIFFNITLRRKTLFYT 265
                |....:.:|.....|.|.. |....|:..:.|    :.|.     ::.|  ||:|:.::|.
  Fly   188 ----DPTTPLVVDENIELPQVAL-IRNETADCTQVYSTGNFTCL-----EVVF--TLKRRLVYYV 240

  Fly   266 VNLIIPCVGISYLSVLVFYL-PADSGEKIALCISILLSQTMFFLLISEIIPSTSLALPLLGKYLL 329
            .|..||...|..:|.:.|:: |..:..::.|.::.||:.:.........:|..|. |..:..::.
  Fly   241 FNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSLLTLSTQHAKSQSSLPPVSY-LKAVDAFMS 304

  Fly   330 FTMLLVGLSV----VITIIILNIHYRKPSTHKMRP 360
            ...:.|.:::    :|.|::.:....||..:..:|
  Fly   305 VCTVFVFMALMEYCLINIVLSDTPIPKPMAYPPKP 339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRalpha2	NP_524482.1	LGIC_ECD_nAChR_proto_alpha-like	44..263	CDD:349832	45/240 (19%)
		LIC	47..544	CDD:273305	65/341 (19%)
ort	NP_524406.1	LIC	31..481	CDD:273305	65/335 (19%)
		Neur_chan_LBD	38..235	CDD:280998	42/220 (19%)
		Neur_chan_memb	243..>334	CDD:280999	17/91 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100