Protein Alignment nAChRalpha2 and pHCl-2

DIOPT Version :9

• Sequence 1: NP_524482.1
• Gene: nAChRalpha2 / 42919
• FlyBaseID: FBgn0000039
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_001303470.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Alignment Length: 352
• Identity: 77/352 - (21%)
• Similarity: 145/352 - (41%)
• Gaps: 59/352 - (16%)

  Fly    56 YNRLIRPVSNNTDTVLVKLGLRLSQLI----DLNLKDQILTTNVWLEHEWQDHKFKWDPSEY--- 113
            |:|::.||.:|.|...|.:.:.....|    :|:..|...|....|:..:.|.:..:  |.|
  Fly    85 YDRMVPPVVHNKDGEEVPMDIYARFYIYVMKNLDSSDLQFTVQGLLQLRYLDPRLAF--SSYLPN 147

  Fly   114 -----GGVTELYVPSEHIWLPDIVLYNNADGEYVVTTMTK---AILHYTGKVVWTPPAIFKSSCE 170
                 .|.:||   .:.:|:|.|.| .|.....|:.|..|   ..::..|.|:.:........|.
  Fly   148 RRQPIMGESEL---KKMLWVPHIFL-TNEQASTVLGTSAKDELTSIYPNGTVLTSTRLQATLYCW 208

  Fly   171 IDVRYFPFDQQTCFMKFGSWTYDGDQIDLKHISQKNDKDNKVEIGIDLREYYPSVEWDILGVPAE 235
            ::.:.||||:|.|.....||.|:...:.|..     :.||.|.....|:    ..|::::|....
  Fly   209 MNFQKFPFDEQKCKTTLESWMYNTTLVQLHW-----ETDNPVSFDKQLQ----LTEYNLIGSLYN 264

  Fly   236 R-----HEKY--YPCCAEPYPDIFFNITLRRKTLFYTVNLIIPCVGISYLSVLVFYLPAD-SGEK 292
            .     :|.|  :......|..|.|.:.|.|:..:|.::..:|.:.|..:|.:.|:|.|| :..:
  Fly   265 ESIRVSNESYMSHGSLEGNYSIISFTVLLTREVGYYVIDYFLPSIMIVTISWVSFWLQADQTPAR 329

  Fly   293 IAL-CISIL------LSQTMFFLLISEIIPSTSLALPLLGKYLLFTMLLVGLSVVITIIILNIHY 350
            ..| |.::|      |||....:.:|.:..|...       :|:.|:.:.|  .::....:|..:
  Fly   330 TTLGCTTLLSFITLSLSQENNLMKVSYVTMSEVW-------FLVCTIFIFG--SLVEFAFVNTIW 385

  Fly   351 RKPSTHKMRP-----WIRSFFIKRLPK 372
            |:.:..:::.     .::|.|:..|.|
  Fly   386 RRNNDLQLKKRTTKYIVKSTFVPHLKK 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRalpha2	NP_524482.1	LGIC_ECD_nAChR_proto_alpha-like	44..263	CDD:349832	52/228 (23%)
		LIC	47..544	CDD:273305	77/352 (22%)
pHCl-2	NP_001303470.1	LIC	46..522	CDD:273305	77/352 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100