Protein Alignment nAChRalpha2 and GluClalpha

DIOPT Version :9

• Sequence 1: NP_524482.1
• Gene: nAChRalpha2 / 42919
• FlyBaseID: FBgn0000039
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_001287408.1
• Gene: GluClalpha / 42350
• FlyBaseID: FBgn0024963
• Length: 463
• Species: Drosophila melanogaster
• Alignment Length: 374
• Identity: 80/374 - (21%)
• Similarity: 149/374 - (39%)
• Gaps: 85/374 - (22%)

  Fly    29 LLVLLLLCETVQAN-------PDAKRLYDDLL--SNYNRLIRPVS-NNTD---TVLVKLGLR-LS 79
            :|....||....||       ...|::.|.:|  ..|:..|||.. |.||   .|.|.:.:| :|
  Fly    10 ILYFASLCSASLANNAKINFREKEKKVLDQILGAGKYDARIRPSGINGTDGPAVVRVNIFVRSIS 74

  Fly    80 QLIDLNLKDQILTTNVWLEHEWQDHKFKWDPSE----YGGVTELYVPSEHIWLPDIVLYNNADGE 140
            ::.|:.::..:..|   ...:|.|.:.|:|..:    |..:||    :..:|:||:...|..:|.
  Fly    75 KIDDVTMEYSVQLT---FREQWTDERLKFDDIQGRLKYLTLTE----ANRVWMPDLFFSNEKEGH 132

  Fly   141 YVVTTMTKAILHY--TGKVVWTPPAIFKSSCEIDVRYFPFDQQTCFMKFGS--WTYDGDQIDLKH 201
            :....|....:..  .|.|:::.......:|.::::.:|.|:|.|.::..|  ||.:    ||..
  Fly   133 FHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTN----DLVF 193

  Fly   202 ISQKNDKDNKVEIGIDLREYYPSVEWDILGVPAERHEKY-------------YPCCAEPYPDIFF 253
            :.::.|....|:               .|.:|....||:             |.|..   .|:.|
  Fly   194 LWKEGDPVQVVK---------------NLHLPRFTLEKFLTDYCNSKTNTGEYSCLK---VDLLF 240

  Fly   254 NITLRRKTLFYTVNLIIPCVGISYLSVLVFYLPADSG---EKIALCISILLSQTMFFLLISEIIP 315
                :|:..:|.:.:.|||..:..:|.:.|:|  |.|   .:::|.::.||:.......|:..:|
  Fly   241 ----KREFSYYLIQIYIPCCMLVIVSWVSFWL--DQGAVPARVSLGVTTLLTMATQTSGINASLP 299

  Fly   316 STSLALPL---LGKYLLFTMLLVGLSVVITIIILNIHYR----KPSTHK 357
            ..|....:   .|..|.|.     ...::...::|...|    |.:.||
  Fly   300 PVSYTKAIDVWTGVCLTFV-----FGALLEFALVNYASRSGSNKANMHK 343

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRalpha2	NP_524482.1	LGIC_ECD_nAChR_proto_alpha-like	44..263	CDD:349832	52/246 (21%)
		LIC	47..544	CDD:273305	74/349 (21%)
GluClalpha	NP_001287408.1	LIC	3..455	CDD:273305	80/374 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100