Protein Alignment nAChRalpha2 and HisCl1

DIOPT Version :9

• Sequence 1: NP_524482.1
• Gene: nAChRalpha2 / 42919
• FlyBaseID: FBgn0000039
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_731632.1
• Gene: HisCl1 / 41426
• FlyBaseID: FBgn0037950
• Length: 426
• Species: Drosophila melanogaster
• Alignment Length: 333
• Identity: 66/333 - (19%)
• Similarity: 122/333 - (36%)
• Gaps: 97/333 - (29%)

  Fly    27 CLLLVLLLL---------CETVQA---NPDAKRL---YDDLLSNYNRLIRPVSNNT--------- 67
            ||:.:.:.|         |..|..   |.::..|   |:..||..:  |.|:.:.|
  Fly    13 CLIALAIYLHALEQSIQHCHCVHGYRNNTESAELVSHYESSLSLPD--ILPIPSKTYDKNRAPKL 75

  Fly    68 --DTVLVKLGLRLSQLIDLNLKDQILTTNVWLEHEWQDHKFK--------------------WDP 110
              ...:|...:.:..|..:|.:.....|:::|...|:|.:.:                    |.|
  Fly    76 LGQPTVVYFHVTVLSLDSINEESMTYVTDIFLAQSWRDPRLRLPENMSEQYRILDVDWLHSIWRP 140

  Fly   111 SEY----GGVT--ELYVPSEHIWLPDIVLYNNADGEYVVTTMTKAILHYTGKVVWTPPAIFKSSC 169
            ..:    ..||  |:.:|:.::|     ||::           |.:| |..|:.      ...||
  Fly   141 DCFFKNAKKVTFHEMSIPNHYLW-----LYHD-----------KTLL-YMSKLT------LVLSC 182

  Fly   170 EIDVRYFPFDQQTCFMKFGSWTYDGDQIDLKHISQKNDK---DNKVEI-GIDLREYYPSVEWDIL 230
            .:....:|.|.|.|.|...|.::..:  ||..|....|.   :.::|: .:|:...|.:
  Fly   183 AMKFESYPHDTQICSMMIESLSHTVE--DLVFIWNMTDPLVVNTEIELPQLDISNNYTT------ 239

  Fly   231 GVPAERHEKYYPCCAEPYPDIFFNITLRRKTLFYTVNLIIPCVGISYLSVLVFYL-PADSGEKIA 294
            ....|.....:.|.|     |.||  |||:..::..:..||...|..:|.:.|:: |.....::.
  Fly   240 DCTIEYSTGNFTCLA-----IVFN--LRRRLGYHLFHTYIPSALIVVMSWISFWIKPEAIPARVT 297

  Fly   295 LCISILLS 302
            |.::.||:
  Fly   298 LGVTSLLT 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRalpha2	NP_524482.1	LGIC_ECD_nAChR_proto_alpha-like	44..263	CDD:349832	51/262 (19%)
		LIC	47..544	CDD:273305	60/301 (20%)
HisCl1	NP_731632.1	Neur_chan_LBD	67..262	CDD:280998	43/232 (19%)
		Neur_chan_memb	270..>350	CDD:280999	9/36 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100