Protein Alignment nAChRalpha2 and Lcch3

DIOPT Version :9

• Sequence 1: NP_524482.1
• Gene: nAChRalpha2 / 42919
• FlyBaseID: FBgn0000039
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_996469.1
• Gene: Lcch3 / 32554
• FlyBaseID: FBgn0010240
• Length: 496
• Species: Drosophila melanogaster
• Alignment Length: 420
• Identity: 81/420 - (19%)
• Similarity: 169/420 - (40%)
• Gaps: 64/420 - (15%)

  Fly    28 LLLVLLLLCETVQANPDAKRL------YDDLLSNYNRLIRPVSNNTDTVLVKLGLRLSQLIDLNL 86
            ||...|.|...::.:..|.||      ..::|..|:..:|| :...:.:.|.:.|.::....::.
  Fly    17 LLGAQLQLIRCIRKDVLAGRLENVTQTISNILQGYDIRLRP-NFGGEPLHVGMDLTIASFDAISE 80

  Fly    87 KDQILTTNVWLEHEWQDHKFK-------WDPSEYGGVTELYVPS----EHIWLPDIVLYNNADG- 139
            .:...|..::|...|:|.:..       :|.....|::::...|    |.||:||....|:.:.
  Fly    81 VNMDYTITMYLNQYWRDERLAFNIFGQYFDDENDDGISDVLTLSGDFAEKIWVPDTFFANDKNSF 145

  Fly   140 EYVVTTMTKAI-LHYTGKVVWTPPAIFKSSCEIDVRYFPFDQQTCFMKFGSWTYDGDQIDL--KH 201
            .:.||...|.: |...|.|.:........:|.:|:.|:|.|.|.|.::..|:.|....:.:  |.
  Fly   146 LHDVTERNKLVRLGGDGAVTYGMRFTTTLACMMDLHYYPLDSQNCTVEIESYGYTVSDVVMYWKP 210

  Fly   202 ISQKNDKDNKVEIGIDLREYYPSVEWDILGVPAERHEKYYPCCAEPYPDIFFNITLRRKTLFYTV 266
            ...:..:|.::.            ::.|:|.  |.:::........|..:..:..|:|...::..
  Fly   211 TPVRGVEDAELP------------QFTIIGY--ETNDRKERLATGVYQRLSLSFKLQRNIGYFVF 261

  Fly   267 NLIIPCVGISYLSVLVFYLPAD-SGEKIALCISILLSQTMFFLLISEIIPSTSLALPLLGKYLLF 330
            ...:|.:.|..||.:.|::..: :..::||.|:.:|:.|.....:...:|..|. :..:..||:.
  Fly   262 QTYLPSILIVMLSWVSFWINHEATSARVALGITTVLTMTTISTGVRSSLPRISY-VKAIDIYLVM 325

  Fly   331 TMLLVGLSVVITIIILNIHYRKPSTHKMRPWIRSFFIKRLPKLLLMRVPKDLLRDLAANKINYGL 395
            ..:.| .:.::....:|..|          |     .||..|    ::.|  :::....||.
  Fly   326 CFVFV-FAALLEYAAVNYTY----------W-----GKRAKK----KIKK--VKECCPGKIG--- 365

  Fly   396 KFSKTKFGQALMDEMQMNSGGSSP-DSLRR 424
            |..:::......|.:::.....|| .||||
  Fly   366 KSERSETCSTTEDIIELQDVRMSPIPSLRR 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRalpha2	NP_524482.1	LGIC_ECD_nAChR_proto_alpha-like	44..263	CDD:349832	45/239 (19%)
		LIC	47..544	CDD:273305	76/401 (19%)
Lcch3	NP_996469.1	LIC	15..493	CDD:273305	81/420 (19%)
		Neur_chan_LBD	47..256	CDD:280998	42/223 (19%)
		Neur_chan_memb	263..490	CDD:280999	32/159 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100