Protein Alignment nAChRalpha1 and NtR

DIOPT Version :9

• Sequence 1: NP_001262916.1
• Gene: nAChRalpha1 / 42918
• FlyBaseID: FBgn0000036
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_651958.2
• Gene: NtR / 43935
• FlyBaseID: FBgn0029147
• Length: 585
• Species: Drosophila melanogaster
• Alignment Length: 379
• Identity: 77/379 - (20%)
• Similarity: 139/379 - (36%)
• Gaps: 77/379 - (20%)

  Fly    13 LHFATGGLANPDAKRLYDDLLSNYNRLIRPVGNNSDRLTVKMGLRLSQL--------IDVNLK-- 67
            |.|::.|  :..|:..||.....|...|.|:.....: |.|:   ||.|        :..||.
  Fly   181 LSFSSFG--SNTARWFYDCGFDGYGSEIAPIVKEETK-TEKL---LSHLNIQAENASMPANLSSI 239

  Fly    68 --------------NQIMTTNVWVEQEWNDYKLKWNPDDYGGVDTLHVPSEHIWLPDIVLYNNA- 117
                          :.::.|.:.:...|.|.:|.|.|:|:|.:::...|...||.|.:.:.|.|
  Fly   240 SFHFQTRSLAYEQTSSLLQTRMHMMMHWRDSRLVWKPEDFGSLESFEHPDLRIWKPHMNVLNGAL 304

  Fly   118 DGNYEVTIMTKAILHHTGKVVWKPPAIY------KSFCEIDVEYFPFDEQTCFMKFGSWTYDGYM 176
            ....:|....:.:::..|.:     .:|      .|:|......:|.:..||.::.|
  Fly   305 QSMGQVLQSYELMVYANGSI-----TLYAQNLQLASWCVDSARNWPSERVTCDIELG-------- 356

  Fly   177 VDLRHLKQTADSDNIEVGIDLQDYYISVE--------WDI--MRVPAVRN--EKFYS---CCEEP 226
                 |......:|:.:..|.|...|:..        |..  |.|..|.|  ::.|:   ..::.
  Fly   357 -----LNGQEGQENVALIYDDQRKPIAPNEHVNTPSGWSFTQMSVVLVENDSQRRYNPKGMMQKM 416

  Fly   227 YLDIVFNLTLRRKTLFYTVNLIIPCVGISFLSVLVFYLPSDSGEKISLCISILLSLTVFFLLLAE 291
            ..|:....||:|...||.....:|.:......:|.|.|.|   .:.|..|.|.|.:..:.|:...
  Fly   417 TGDVAIEFTLQRNRSFYMTVFYLPLIACQMFLILSFVLRS---TRRSSLILIALLIAAWGLMYMT 478

  Fly   292 IIPPTSLTVPLLGKYLLFTMMLVTLSVVVTIAVLNVNFRSPVTHRMAP-WVQRL 344
            .........|::..|.:. ||..|...::.|.::.::...|  ...|| |:.|:
  Fly   479 RYASPHYVPPMMTAYKVI-MMTTTYCYILHICIIWLDLYPP--RSKAPGWLVRV 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRalpha1	NP_001262916.1	Neur_chan_LBD	25..240	CDD:280998	51/260 (20%)
		LIC	27..530	CDD:273305	73/365 (20%)
		Neur_chan_memb	247..530	CDD:280999	21/99 (21%)
NtR	NP_651958.2	Methyltransf_FA	90..191	CDD:289052	3/11 (27%)
		Neur_chan_LBD	212..429	CDD:280998	44/238 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3645
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910