Protein Alignment nAChRalpha1 and alka

DIOPT Version :10

• Sequence 1: NP_001262916.1
• Gene: nAChRalpha1 / 42918
• FlyBaseID: FBgn0000036
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_610619.2
• Gene: alka / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Alignment Length: 338
• Identity: 71/338 - (21%)
• Similarity: 134/338 - (39%)
• Gaps: 53/338 - (15%)

  Fly    35 NYNRLIRPVGNNSDRLTVKMGLRLSQLIDVNLKNQIMTTNVWVEQEWNDYKLK------WNPDDY 93
            ||.:.|||.......:.|...:.:..:..:|:::.....::::.|.|.:.:|:      ...|||
  Fly    43 NYVKEIRPPSKKGSPVIVDFSIFVVDINSINVEDMDFRVDMFIHQRWLESRLEIPDDIFEEGDDY 107

  Fly    94 GGVDTLHVPSEHIWLPDIVLYNNADGNYEVTIMTKAILHH--TGKVVWKPPAI-YKS------FC 149
              |..|....|:.|.||....|:       .|...|.|.|  |...::|...: |.:      .|
  Fly   108 --VTLLPEVFENFWQPDPYFLNS-------KIAEIATLTHKFTSVTLYKNKTVRYAARMHAIIAC 163

  Fly   150 EIDVEYFPFDEQTCFMKFGSWTYDGYMVDLRHLKQTADSD-NIEVGIDLQDYYISVEWDIMRVPA 213
            :::.:.:|.|.|.|.:...|::.:...|.||    .:||. .:...:.|..|.:....::.....
  Fly   164 QMEFQLYPMDIQVCPIYIESFSSNNQKVKLR----WSDSGVTLNPELKLLQYNLGQPLELEESDG 224

  Fly   214 VRNEKFYSCCEEPYLDIVFNLTLRRKTLFYTVNLIIPCVGISFLSVLVFYLPSDS-GEKISLCIS 277
            ...||..:...   |.:.|.  ..|:...:.:....|...:..||...|:|..|: ..:::|.::
  Fly   225 YMPEKVGNFSR---LTVYFR--FERQIGHHLIQTFAPSSLVVMLSWFSFWLGLDAIPGRVTLLVT 284

  Fly   278 ILLSLTVFFLLLAEIIPPTSLTVPLLGKYLLFTMMLV--TLSVVVTIAVLNVNFRSPVTHRMAPW 340
            .:|:|...|  ....|||.:. |..|..::...|:.|  .|:..|.:.||:|.::..|..
  Fly   285 CMLTLVTMF--TGADIPPVAY-VKALDLWMAGCMLSVFAALAEFVVVKVLDVQYQYQVNR----- 341

  Fly   341 VQRLFIQILPKLL 353
                    :||:|
  Fly   342 --------IPKVL 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRalpha1	NP_001262916.1	LGIC_ECD_nAChR_proto_alpha-like	24..242	CDD:349832	45/222 (20%)
		LIC	27..530	CDD:455710	71/338 (21%)
		Cys-loop	149..163	CDD:349832	4/13 (31%)
alka	NP_610619.2	LIC	8..441	CDD:455710	71/338 (21%)