Protein Alignment nAChRalpha1 and CG8916

DIOPT Version :9

• Sequence 1: NP_001262916.1
• Gene: nAChRalpha1 / 42918
• FlyBaseID: FBgn0000036
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Alignment Length: 399
• Identity: 84/399 - (21%)
• Similarity: 162/399 - (40%)
• Gaps: 64/399 - (16%)

  Fly    16 ATGGLANPDAKRLYDDLLSNYNRLIRPVGNNSDRLTVKMGLRLSQLIDVNLKNQIMTTNVWVEQE 80
            |...:.:.:...:.::||..|.:...|.........|:..:.:..:..|:..:...:.:.:..|.
  Fly    99 AAADMLSRNISMILENLLKRYEQSQLPTHGQGVPTVVQTNILIRSMGPVSELDMDYSMDCYFRQY 163

  Fly    81 WNDYKLKWNPDDYGGVDTLHVP---SEHIWLPDIVLYNNADGN-YEVTIMTKAI-LHHTGKVVWK 140
            |.|.:|.:.    |.:.:|.:.   .:.||.||...||..... :.:|:..|.: |...|.:::.
  Fly   164 WRDKRLSFK----GPIKSLSLSIKMLDKIWRPDTYFYNGKHSQIHMITVPNKLLRLDQNGGILYS 224

  Fly   141 PPAIYKSFCEIDVEYFPFDEQTCFMKFGSWTYDGYMVDLRHLKQTADSDNIEVGIDLQDYYISVE 205
            .....|:.|.::::.||.|.|:|.:..||:.|....: :...|...|:.:...|:.|.      :
  Fly   225 MRLTIKATCPMELQNFPMDRQSCPLVIGSYGYINQQL-IYEWKNQDDAVSFVPGMTLN------Q 282

  Fly   206 WDIMRV-----PAVRNEKFYSCCEEPYLDIVFNLTLRRKTLFYTVNLIIPCVGISFLSVLVFYLP 265
            :|::.:     ..||.|..:|     .|.:.||  |:|.|.::.:.:.:||:.|..||.:.|::.
  Fly   283 FDLISMMHRNFTTVRREGDFS-----VLHVAFN--LKRHTGYFLIQVYVPCILIVVLSWVSFWIH 340

  Fly   266 SD-SGEKISLCISILLSLTVFFLLLAEIIPPTSLTVPLLGKYLLFTMMLVTLSVVVTIAVLNVNF 329
            .: :.:::|||::.:|:|:...|.....:|..        ||.......:.:|.:..||.| :.|
  Fly   341 REATSDRVSLCVTSVLTLSTISLDSRTDLPKV--------KYATALDWFLLMSFLYCIATL-LEF 396

  Fly   330 RSPVTHRMAPWVQRLFIQILPKLLCIERPKKEEPEE---------DQPPEVLTDVYHLPPDVDKF 385
            ..              :....||...|.|:.|:..|         |...||..|.   ..|.|.|
  Fly   397 AG--------------VHYFTKLGSGESPQLEDQWEDICIANSLSDHAGEVDGDG---EADADPF 444

  Fly   386 VNYDSKRFS 394
            .:.||...|
  Fly   445 ADEDSSNGS 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRalpha1	NP_001262916.1	Neur_chan_LBD	25..240	CDD:280998	46/224 (21%)
		LIC	27..530	CDD:273305	83/388 (21%)
		Neur_chan_memb	247..530	CDD:280999	36/158 (23%)
CG8916	NP_573090.3	LIC	92..598	CDD:273305	84/399 (21%)
		Neur_chan_LBD	111..315	CDD:280998	46/221 (21%)
		Neur_chan_memb	322..>403	CDD:280999	20/103 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100