Protein Alignment nAChRalpha1 and lgc-9

DIOPT Version :9

• Sequence 1: NP_001262916.1
• Gene: nAChRalpha1 / 42918
• FlyBaseID: FBgn0000036
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_500341.1
• Gene: lgc-9 / 182195
• WormBaseID: WBGene00015412
• Length: 464
• Species: Caenorhabditis elegans
• Alignment Length: 337
• Identity: 95/337 - (28%)
• Similarity: 165/337 - (48%)
• Gaps: 38/337 - (11%)

  Fly    28 LYDDLLSNYNRLIRPVGNNSDRLTVKMGLRLSQLIDVNLKNQIMTTNVWVEQEWNDYKLKWNPDD 92
            |.:.:...|::.:||...::..:.|.|.:.|..|.:|....|:.:..:...|:|.|.||.|||.|
 Worm    44 LIETIQRRYDKRVRPFAESNRPVIVHMTIVLGILTEVRENQQVASFVISHVQKWRDPKLAWNPAD 108

  Fly    93 YGGVDTLHVPSEHIWLPDIVLYNN-------ADGNYEVTIMTKAILHHTGKVVWKPPAIYKSFCE 150
            :.|:..:.:|...:|:|.:.:||:       .|..|:|.|      .|||.|....|....:.|.
 Worm   109 HSGLTQVVMPRSLVWVPKLFIYNSMDTKDMLTDDRYDVRI------QHTGHVKVNSPQFVSTLCR 167

  Fly   151 IDVEYFPFDEQTCFMKFGSWTYDGYMVDLRHLKQTADSDNIEVGIDLQDYYIS--VEWDIMRVPA 213
            |:::.||||.|.|.:...|.......:|:...:...||            |.|  .||.:|.| .
 Worm   168 INIDLFPFDTQFCAIALASPLLSVEEMDVNATQPPVDS------------YFSGNAEWQVMNV-T 219

  Fly   214 VRNEKFYSCCEEPY-LDIVFNLTLRRKTLFYTVNLIIPCVGISFLSVLVFYLP-SDSG---EKIS 273
            |:..||..  |..| .::.:.|.|.|:..:|...:::|...||.||:|..:.| |:.|   ||:|
 Worm   220 VKQMKFME--EGEYRAEVHYILHLNRRPTYYITVIVVPTFLISALSILGIFSPGSNDGPRNEKVS 282

  Fly   274 LCISILLSLTVFFLLLAEIIPPTSLTVPLLGKYLLFTMMLVTLSVVVTIAVLNVNFRSPVTHRMA 338
            |.:..||::||...::|..:|.:. .:||||.|::..::|..:.|.|::|:|:::.....|.:|.
 Worm   283 LGLGSLLAMTVLLDIVAGAMPKSD-AIPLLGYYIMLVILLCAIGVAVSMAMLSMSRSCIQTSKMP 346

  Fly   339 P--WVQRLFIQI 348
            |  :.:.||:.:
 Worm   347 PPHYYRLLFLNV 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRalpha1	NP_001262916.1	Neur_chan_LBD	25..240	CDD:280998	60/221 (27%)
		LIC	27..530	CDD:273305	95/337 (28%)
		Neur_chan_memb	247..530	CDD:280999	34/108 (31%)
lgc-9	NP_500341.1	Neur_chan_LBD	42..245	CDD:280998	60/221 (27%)
		Neur_chan_memb	252..>347	CDD:280999	31/95 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3645
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810