DRSC/TRiP Functional Genomics Resources

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Protein Alignment MLF1 and mlf1

DIOPT Version :10

Sequence 1:NP_001356712.1 Gene:MLF1 / 4291 HGNCID:7125 Length:283 Species:Homo sapiens
Sequence 2:NP_001313302.2 Gene:mlf1 / 553527 ZFINID:ZDB-GENE-080917-7 Length:258 Species:Danio rerio


Alignment Length:289 Identity:123/289 - (42%)
Similarity:167/289 - (57%) Gaps:43/289 - (14%)


- Green bases have known domain annotations that are detailed below.


Human     2 FRMLNSSFEDDPFF---SESILAHRENMRQMIRSFSEPFGRDLL-SISD--GRGRAHNRRGHNDG 60
            ||.|    |:||||   |:....|.|.||||:..||:||.:..: ||:|  .||..|...|....
Zfish     4 FRQL----EEDPFFASSSDPFRLHHERMRQMMGGFSDPFAQSFMPSITDVHQRGHRHPNTGPRQR 64

Human    61 EDSLTATSCSLVPFGDFGGMHTDVSSFQTMDQMVSNMRNYMQKLERNFGQL-SVDPNGHSFCSSS 124
            .|                   .::..|.....|:.:|||.|:.:.|:...: |.|.:.|||.|||
Zfish    65 SD-------------------RELDFFANPFSMMESMRNRMEAMHRHTDSMSSPDSSSHSFSSSS 110

Human   125 VMTYSKIGDEPPKVFQASTQTRRAPGGIKETRKAMRDSDSGLEKMAIGHHIHDRAHVIKKSKNKK 189
            ||||||:||||.|||.||:|||.||||||||:|::|||:|||:||:|||||.||.|||::.:|:|
Zfish   111 VMTYSKVGDEPAKVFAASSQTRCAPGGIKETKKSLRDSESGLQKMSIGHHIQDRGHVIERKENRK 175

Human   190 TGDEEVNQEFINMNESDAHAFDEEWQSEVLKYKPGRHNLGNTRMRSVGHENPGSRELKRR--EKP 252
            ||::|.||:|.||:|::|.|||:|||.||.:::.   :....|:     |.|..|.:.|.  ..|
Zfish   176 TGEKEFNQDFQNMDETEAQAFDQEWQQEVSRFQV---SAPTARL-----EAPKHRTVHRAAITAP 232

Human   253 QQSPAIEHGRRSNVLGDKLHIKGSSVKSN 281
            |.:.........|   .|||:.|||||.:
Zfish   233 QHTHRDSRAAEGN---QKLHMTGSSVKKH 258

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MLF1NP_001356712.1 Mlf1IP 26..217 CDD:463022 94/194 (48%)
mlf1NP_001313302.2 None

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