Protein Alignment CG18528 and mnmE

DIOPT Version :10

• Sequence 1: NP_651251.3
• Gene: CG18528 / 42906
• FlyBaseID: FBgn0039189
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_418162.1
• Gene: mnmE / 948222
• ECOCYCID: EG10997
• Length: 454
• Species: Escherichia coli
• Alignment Length: 487
• Identity: 164/487 - (33%)
• Similarity: 248/487 - (50%)
• Gaps: 47/487 - (9%)

  Fly    20 SSGCTIYSLSSGHVKCGVSVIRVSGPQTKKALRAIVANKEYEPKARQA-YLKSFYHPASKEMIDR 83
            |...||.:.::...:.||.::|:||.:.::....::...   ||.|.| ||.  :..|...::|:
E. coli     2 SDNDTIVAQATPPGRGGVGILRISGFKAREVAETVLGKL---PKPRYADYLP--FKDADGSVLDQ 61

  Fly    84 GLLLWFPGPASFTGEDSCEFQVHGSLAVIAAMLDALGKVDGLRPAEPGEFTKRAFFGGKLDLTEV 148
            |:.||||||.||||||..|.|.||...::..:|..:..:.|||.|.||||::|||...||||.:.
E. coli    62 GIALWFPGPNSFTGEDVLELQGHGGPVILDLLLKRILTIPGLRIARPGEFSERAFLNDKLDLAQA 126

  Fly   149 EGLADLIHAETEAQRKQALLQSTGALARLYDNWRRRLIRCAAHLEAYIDFAEEE---QIEGGIIL 210
            |.:||||.|.:|...:.||....||.:...::....|.....::||.|||.:||   ..:|.|..
E. coli   127 EAIADLIDASSEQAARSALNSLQGAFSARVNHLVEALTHLRIYVEAAIDFPDEEIDFLSDGKIEA 191

  Fly   211 QLG---KELKAVKREIREHLSDQRQGELLRDGVRTVIIGAPNVGKSSLLNLLCQRSVSIVTDQAG 272
            ||.   .:|.||:.|       .|||.|||:|::.||.|.||.|||||||.|..|..:||||.||
E. coli   192 QLNDVIADLDAVRAE-------ARQGSLLREGMKVVIAGRPNAGKSSLLNALAGREAAIVTDIAG 249

  Fly   273 TTRDIIETMHNFGGYPVVFSDTAGLRRYTTDSIEQEGMQRAKNCLVQSDLILLLAEAKNIAQLTH 337
            ||||::....:..|.|:...||||||. .:|.:|:.|::||...:.|:|.:|.:.:.      |.
E. coli   250 TTRDVLREHIHIDGMPLHIIDTAGLRE-ASDEVERIGIERAWQEIEQADRVLFMVDG------TT 307

  Fly   338 DDAVAP--FVDSYLGELDIPLDMCSGKRLQLVANKTDTLTDEEHQQLDKLSNVL-AISCHKPDKM 399
            .|||.|  ....::..|...|.      :.:|.||.| :|.|.....:...:.| .:|....:.:
E. coli   308 TDAVDPAEIWPEFIARLPAKLP------ITVVRNKAD-ITGETLGMSEVNGHALIRLSARTGEGV 365

  Fly   400 PVFLGSLEKQLQELCG-EPRAENPRITNTRYRQQLERCIENIDIFLRDYRPDVYPDMA--IAASK 461
            .|    |...|::..| :...|...:...|:.|.||:..|:    |:..:..:....|  :.|.:
E. coli   366 DV----LRNHLKQSMGFDTNMEGGFLARRRHLQALEQAAEH----LQQGKAQLLGAWAGELLAEE 422

  Fly   462 LRNSVRCIERITGHISCEDILDVVFKDFCIGK 493
            ||.:.:.:..|||..:.:|:|..:|..|||||
E. coli   423 LRLAQQNLSEITGEFTSDDLLGRIFSSFCIGK 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18528	NP_651251.3	MnmE	24..493	CDD:440253	161/481 (33%)
mnmE	NP_418162.1	trmE	1..454	CDD:235392	162/485 (33%)