DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18528 and gtpbp3

DIOPT Version :9

Sequence 1:	NP_651251.3	Gene:	CG18528 / 42906	FlyBaseID:	FBgn0039189	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	XP_004911076.1	Gene:	gtpbp3 / 100490486	XenbaseID:	XB-GENE-988214	Length:	496	Species:	Xenopus tropicalis

Alignment Length:	481	Identity:	223/481 - (46%)
Similarity:	309/481 - (64%)	Gaps:	27/481 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 TIYSLSSGHVKCGVSVIRVSGPQTKKALRAIVANKEYEPKARQAYLKSFYHPASKEMIDRGLLLW 88
            ||::|||||.||||||||.|||.:..||:.:...|:. |..|:..|.|...|.:.|::||||:||
Frog    32 TIFALSSGHGKCGVSVIRTSGPASGDALQLLTGWKQL-PPPRRVTLTSLLCPTTGELLDRGLVLW 95

  Fly    89 FPGPASFTGEDSCEFQVHGSLAVIAAMLDALGKVDGLRPAEPGEFTKRAFFGGKLDLTEVEGLAD 153
            |.||.||||||.||:.|||..||:..:|.|||.|..||||||||||||||..|||||||.|||.|
Frog    96 FSGPKSFTGEDCCEYHVHGGPAVVMGVLQALGTVQMLRPAEPGEFTKRAFQNGKLDLTEAEGLGD 160

  Fly   154 LIHAETEAQRKQALLQSTGALARLYDNWRRRLIRCAAHLEAYIDFAEEEQIEGGIILQLGKELKA 218
            |||||||.||:|||.|.:|.|.:||..|..||:...||:||:|||:|::.:|..::..:..|:|.
Frog   161 LIHAETEIQRRQALRQMSGELGQLYQKWSHRLVTALAHVEAFIDFSEDDNVEENVLTSVDSEVKN 225

  Fly   219 VKREIREHLSDQRQGELLRDGVRTVIIGAPNVGKSSLLNLLCQRSVSIVTDQAGTTRDIIETMHN 283
            ::.|:.:||.|.|:||.||||:..|:.||.|.||||||||..|:..:||:...|||||::||:.|
Frog   226 LQEELEDHLKDSRRGERLRDGLHLVLAGATNAGKSSLLNLTSQKPAAIVSPIPGTTRDVVETVLN 290

  Fly   284 FGGYPVVFSDTAGLRRYTTDSIEQEGMQRAKNCLVQSDLILLLAEAK-----NIAQLTHDDAVAP 343
            .|||||:.|||||||. :.|.:|:||::|||..|..:|:::.:.:|.     .|:.|.|..::..
Frog   291 IGGYPVIMSDTAGLRD-SEDPVEKEGVRRAKERLDNADILIAVVDASKVPITRISILAHLKSLLS 354

  Fly   344 FVDSYLGELDIPLDMCSGKRLQLVANKTDTLTDEEH---QQLDK---LSNVLAISCHKPDKMPVF 402
            |..|. |:|         :.:.||.||:|.|....|   |:|.|   |.....:||.....:..|
Frog   355 FPSSE-GKL---------REVLLVLNKSDLLDPPGHAKVQELCKDPELPTACFLSCQTGQGVGDF 409

  Fly   403 LGSLEKQLQELCGEPRAENPRITNTRYRQQLERCIENIDIFLRDYRPDVYPDMAIAASKLRNSVR 467
            :..|:::|:::||:|....|.:|.||:|..|.:|:|.::.: ..||..   |:.:||.:||.|.|
Frog   410 IYILKQKLEKICGDPLHGAPSLTQTRHRLHLNKCLEALEQY-TIYREQ---DLVLAAEELRISYR 470

  Fly   468 CIERITGHISCEDILDVVFKDFCIGK 493
            .:..|||.:..|.|||::|:||||||
Frog   471 ELGAITGRVGVEGILDIIFRDFCIGK 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18528	NP_651251.3	trmE	24..493	CDD:235392	221/479 (46%)
		TrmE_N	24..142	CDD:287381	68/117 (58%)
		trmE	237..415	CDD:206727	71/188 (38%)
gtpbp3	XP_004911076.1	trmE	31..496	CDD:235392	221/479 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	260	1.000	Domainoid score	I1941
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H6600
Inparanoid	1	1.050	403	1.000	Inparanoid score	I1863
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D280742at33208
OrthoFinder	1	1.000	-	-		FOG0003953
OrthoInspector	1	1.000	-	-		oto103491
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2256
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.060