Protein Alignment Golgin84 and Golga5

DIOPT Version :10

• Sequence 1: NP_651250.2
• Gene: Golgin84 / 42905
• FlyBaseID: FBgn0039188
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_001028237.2
• Gene: Golga5 / 299258
• RGDID: 1308163
• Length: 729
• Species: Rattus norvegicus
• Alignment Length: 735
• Identity: 188/735 - (25%)
• Similarity: 302/735 - (41%)
• Gaps: 239/735 - (32%)

  Fly     3 SWITGLADKAENILNKLDQNAATALQTENA------------------------TG--------S 35
            ||...||.:||::||::||.|||||:.|:.                        ||        :
  Rat     2 SWFADLAGRAEDLLNRVDQGAATALRKESTSNTFYSKNTDYPELHQQNTDSTYHTGQKANYISSA 66

  Fly    36 ADPMRR---------------SMTSSTQSLSTSLKSTLSP----VRRSGA-----------NSSS 70
            ||.:|.               |.|....|..|...|...|    |||..:           |||.
  Rat    67 ADNIRHQKATIIAGTANVKVGSRTGGDASHPTEHASVPRPSSHFVRRKKSEPDDELLFDFLNSSQ 131

  Fly    71 -------SVKSDGG------------VSVVTKDMRQ-KMTTSASFSNSPDIS------------- 102
                   .:|.:.|            ||.||..:.. |.|...|.|.||::|
  Rat   132 KEPTGRVEIKKEKGKAPVLPSSQSSAVSSVTTSVTTIKATEENSGSQSPEVSSSDSMPEGHKKST 196

  Fly   103 -------ANSMD----------TNELAAFKI----------ALN-----------EITAERDELR 129
                   |.|::          ::||:..::          :||           |...|.::.|
  Rat   197 EESTVSNATSVEHSSAPSDGSMSHELSNLRLENQLLRNEVQSLNQEMASLLQRSKETQEELNKAR 261

  Fly   130 LRLEDLNNETEKFD------------------------------LHQHTQVL----EALVKSLSE 160
            :|:|..|.:..|.|                              |.:..|||    ||| ::|..
  Rat   262 VRVEKWNVDNSKSDRITRELRAQVDDLTEAVAAKDSQLAVLKVRLQEADQVLSSRTEAL-EALQS 325

  Fly   161 ERDKAVHDYNEAQA-ANMA---------------------YVHSISELETNLAKLQ------QEY 197
            |:.:.:.|:||..: .|.|                     |....||..|.|.|::      .|.
  Rat   326 EKSRIMQDHNEGSSLQNQALQTLQERLHEADATLKREQESYKQMQSEFATRLNKMEVERQNLAEA 390

  Fly   198 ISAAHK-----------LQMQTK----ETEQQRQELQEYRIKAQRALQAKDSLIAELKAKPTEEG 247
            ::.|.:           ||.|.|    ..|..:|||.:|:.||.|.||:|:.||..||...:.||
  Rat   391 VTLAERKYSEERKKVDDLQQQVKLHRSSLESAKQELVDYKQKATRILQSKEKLINSLKEGSSFEG 455

  Fly   248 ADPNLVSKDSETRFLQIEHESLKQELEHANEELQKARLQLDDYVSQ----ERQRQVELSSARQRE 308
            .|.:..|        .:|.|.|:.|.|...||:||...|:....|:    |.|:..|..|||::.
  Rat   456 LDSSTAS--------SMELEELRHERELQKEEIQKLMGQIHQLRSELQDMEAQQVSEAESAREQL 512

  Fly   309 ETLAKELRQAREHSVTSESDQRVLTQELASLRQQLSNQMAAAATRLQEREQQLQQMRQRLSEEA- 372
            :.|..::.:.|......|::...:.||...:.:.|........:|:::||:::|::|.:|:.:.
  Rat   513 QDLQDQIAKQRASKQELETELDRMKQEFHYVEEDLHRTKNTLQSRIKDREEEIQKLRNQLTNKTL 577

  Fly   373 NTGAKSDYETRLKALTQSLVERQSLLERVTSERNALRLQHEKAQTQLQQNMHLVEMESQRGSSRH 437
            :..::|:.|:||..||::|:::|:|||.:::|:|:|..|.|:    |:|.:|........|||.:
  Rat   578 SNSSQSELESRLHQLTETLIQKQTLLESLSTEKNSLVFQLER----LEQQLHSAATGPSSGSSIN 638

  Fly   438 TMLNSTDDVKA----QFPLLMHPSPFDNRVARRF---KRALRQADSMGIRVGTFLRRYPMMRVSV 495
              ::..|..:.    ..|:|.:.:  :..:|..:   ::|....|...||:|.||||||:.||.|
  Rat   639 --MSGVDSGEGTRLRNVPVLFNDT--ETNLAGMYGKVRKAASSIDQFSIRLGIFLRRYPIARVFV 699

  Fly   496 IVYVALLHLWVMFVLLSTTP 515
            |:|:||||||||.|||:.:|
  Rat   700 IIYMALLHLWVMIVLLTYSP 719

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Golgin84	NP_651250.2	hsdR	136..>230	CDD:236912	37/170 (22%)
		Golgin_A5	210..515	CDD:462900	101/316 (32%)
Golga5	NP_001028237.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	88..202		25/113 (22%)
		Smc	<226..>558	CDD:440809	78/340 (23%)
		Golgin_A5	418..722	CDD:462900	102/318 (32%)