Protein Alignment Golgin84 and T24B1.1

DIOPT Version :9

• Sequence 1: NP_651250.2
• Gene: Golgin84 / 42905
• FlyBaseID: FBgn0039188
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_492137.1
• Gene: T24B1.1 / 172527
• WormBaseID: WBGene00011975
• Length: 551
• Species: Caenorhabditis elegans
• Alignment Length: 597
• Identity: 138/597 - (23%)
• Similarity: 253/597 - (42%)
• Gaps: 134/597 - (22%)

  Fly     3 SWITGLAD---KAENILNKLDQNAATALQTENATGSADPMRRSMTSSTQSLSTSLKSTL------ 58
            ||::.::|   .|||:|||||:....|:|  ||..||...|:|.|:|..:...|:...:
 Worm     2 SWLSKVSDIAGAAENLLNKLDEKTGDAIQ--NARDSAPRTRKSSTASVSATIISMPEHVITEDFG 64

  Fly    59 -----SPVR----------RSGAN--SSSSVKSDGGVSVVT------------------KDMRQK 88
                 .|.|          |.|.|  ..||.....||:..:                  :|.|.:
 Worm    65 RPAPSLPSRAQSDYTGAGWRGGRNYEQGSSSTHQPGVTAASESWTMVLNSKEVKNAKPDEDTRSQ 129

  Fly    89 MTTS----ASFSNSPDISANSMDTN----------ELAAFKIALNEI--------------TAER 125
            .:..    ||...:.:.:.|....|          :::..|..|:|:              .||:
 Worm   130 RSVGGRSVASIRTTSEFAGNDSSPNFKSQLFAKDSQISVLKTKLSEVERKFEKRSQDYYEMKAEK 194

  Fly   126 DELRLRLEDLNNETEKFDLHQHTQVLEALVKSLSEERDKAVHDYNEAQAANMAYVHSISELETNL 190
            :.|..|:|:....:.:.|   ..|.|:...:...::::|||.:.|         :|     :..:
 Worm   195 EMLEKRVENQKVSSHEMD---SLQELKLARQKAQDQKEKAVEECN---------MH-----KRKI 242

  Fly   191 AKLQQEYISAAHKLQMQTKETEQQRQELQEYRIKAQRALQAKDSLIAELKAKPTEEGADPNLVSK 255
            ..|::|..:...:|::......:.::|..||:.|||:.|.||:.|:..||   :|:|    :.|.
 Worm   243 VGLEEEIRAMVEQLRLAKFNLNENKKEFDEYKNKAQKILTAKEKLVESLK---SEQG----IGSS 300

  Fly   256 DSETRFLQIEHESLKQELEHANEELQKARLQLDDYVSQERQRQVELSSARQREETLAKELRQARE 320
            |.....||.|.|.::.|.:....:|:.|:||:  |..:....::| :..|..:..|:.:.|...|
 Worm   301 DRPVHLLQAEVEEIRVERDLTKADLESAQLQV--YTLRSDMEELE-AQIRDLQSQLSDQKRTHLE 362

  Fly   321 HSVTSESDQRVLTQELASLR-------QQLSNQMAAAATRLQEREQQLQQ----MRQRLSEEANT 374
            ...|.:|...:|.:::...|       |::..|.....:::.|:|.:|::    :|.|:.:| .|
 Worm   363 EKQTWDSTIGLLNEKVECSRIENEFTKQEMKRQGDQHQSKMLEKENELRKTISDLRSRMRDE-QT 426

  Fly   375 GAKSDYETRLKALTQSLVERQSLLERVTSERNALRLQHEKAQTQLQQNMHL-VEMESQRGSSRHT 438
            ..:.|..::   ||..|:::|..||.|......|.::.|:.|....:...: |:..|   |..||
 Worm   427 KQEDDGSSQ---LTDLLLQKQQQLEDVLRNNQVLNVRLERLQKATNRETSIAVDSNS---SPMHT 485

  Fly   439 MLNSTDDVKAQFPLLMHPSPFDNRVARRFKRALRQADSMGIRVGTFLRRYPMMRVSVIVYVALLH 503
                    .:..|||   |..:|...|   .||...||...::.:.||.:|..|:..::|..::|
 Worm   486 --------SSSHPLL---SNINNPQTR---NALHTVDSTAFKLLSMLRGHPSARLFFVLYFIIMH 536

  Fly   504 LWVMFVLLSTTP 515
            ||:.|::|:.||
 Worm   537 LWLFFIVLTYTP 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Golgin84	NP_651250.2	Golgin_A5	13..505	CDD:255554	128/572 (22%)
T24B1.1	NP_492137.1	Golgin_A5	89..538	CDD:255554	105/496 (21%)
		GBP_C	<267..424	CDD:303769	42/166 (25%)
		coiled coil	398..409	CDD:293879	2/10 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166025
Domainoid	1	1.000	89	1.000	Domainoid score	I4991
eggNOG	1	0.900	-	-		E1_KOG4677
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4951
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005421
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_107022
Panther	1	1.100	-	-	LDO	PTHR13815
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2550
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.680