Protein Alignment CG6432 and prpE

DIOPT Version :10

• Sequence 1: NP_651247.1
• Gene: CG6432 / 42901
• FlyBaseID: FBgn0039184
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_414869.1
• Gene: prpE / 946891
• ECOCYCID: G6200
• Length: 628
• Species: Escherichia coli
• Alignment Length: 637
• Identity: 249/637 - (39%)
• Similarity: 379/637 - (59%)
• Gaps: 26/637 - (4%)

  Fly    32 YRQSVQNPAAFWEEQGNLLDWDRPWEKVLDNSNPPFTKWYVGGYLNACYNSIDRHILAGRGSNVA 96
            |::|:..|..||.||...:||..|:.:.||:|||||.:|:..|..|.|:|:|||. |..:...:|
E. coli     7 YQRSINEPEQFWAEQARRIDWQTPFTQTLDHSNPPFARWFCEGRTNLCHNAIDRW-LEKQPEALA 70

  Fly    97 LIHDSPLTGTLRRVTYQELYDQIVLLAGGLAKLGVVKGDRVVIYMPLIPETIIAMLAIVRLGAIH 161
            ||..|..|...|..|:::|:|::..:|..|..|||.:||||::|||:|.|..|.:||..|:||||
E. coli    71 LIAVSSETEEERTFTFRQLHDEVNAVASMLRSLGVQRGDRVLVYMPMIAEAHITLLACARIGAIH 135

  Fly   162 SVVFGGFAARELCSRIEHVEPKLVIASNVGVEPGKVVPYLDILHSAISMSRWRPPQRNIIFRRDN 226
            ||||||||:..:.:||:..:|.|:::::.|...||::||..:|..|||.::.:|  |:::.
E. coli   136 SVVFGGFASHSVAARIDDAKPVLIVSADAGARGGKIIPYKKLLDDAISQAQHQP--RHVLL---- 194

  Fly   227 VSPDTTKLDPLT--DVLWSDILKMAEGER-PIACVPIEANDPLYILYTSGTTDKPKGVLRTIGGH 288
            |.....|:..::  ||.::.:.....|.| |:|.  :|:|:...||||||||.|||||.|.:||:
E. coli   195 VDRGLAKMARVSGRDVDFASLRHQHIGARVPVAW--LESNETSCILYTSGTTGKPKGVQRDVGGY 257

  Fly   289 LVALVYTLRTLYGINPGHTWWAASDMGWVVGHSYICYGPLCLGATSVMYEGKPDRTPDPGQYFRI 353
            .|||..::.|::|...|..::.|||:|||||||||.|.||..|..:::|||.| ..||.|.::.|
E. coli   258 AVALATSMDTIFGGKAGSVFFCASDIGWVVGHSYIVYAPLLAGMATIVYEGLP-TWPDCGVWWTI 321

  Fly   354 IDQYQVRSIFSVPTSFRVIRRADPDISYGRQYSMKSLRAIFIAGEHCDYETKSWIEKTFKVPVLN 418
            :::|||..:||.||:.||:::. |.... |::.:.||..:::|||..|..|.||:..|..|||::
E. coli   322 VEKYQVSRMFSAPTAIRVLKKF-PTAEI-RKHDLSSLEVLYLAGEPLDEPTASWVSNTLDVPVID 384

  Fly   419 HWWQTETGSAVTATCLGFQQNLSPPTY--STGLPLMGYDVKIL-KADGSEAQTSELGRIALKLPL 480
            ::||||:|..:.|...|....   ||.  |.|:|:.||:|::| :..|.....:|.|.:.::.||
E. coli   385 NYWQTESGWPIMAIARGLDDR---PTRLGSPGVPMYGYNVQLLNEVTGEPCGVNEKGMLVVEGPL 446

  Fly   481 PPGNMATLYKNEELFRTLYFQKFP-GYYDTMDAGYKDERGYIFVTARDDDVINVAGHRLSTSSLE 544
            |||.:.|::.::..|...|:..|. ..|.|.|.|.:|..||.|:..|.|||||||||||.|..:|
E. coli   447 PPGCIQTIWGDDGRFVKTYWSLFSRPVYATFDWGIRDADGYHFILGRTDDVINVAGHRLGTREIE 511

  Fly   545 DAVLRHPDVVDVAVFGVPEATKGQVPLCLYIPVE--NCKKTDAKLSTE--IIKLIRDVVGPIAAF 605
            :::..||.|.:|||.||.:|.||||.:...||.|  :.:..|...|.|  |:.|:...:|.....
E. coli   512 ESISSHPGVAEVAVVGVKDALKGQVAVAFVIPKESDSLEDRDVAHSQEKAIMALVDSQIGNFGRP 576

  Fly   606 RLVTSVNNLPRTRSGKTMRKAMADFARNERVVLPATIDDASVFIEIRRALNQ 657
            ..|..|:.||:|||||.:|:.:.............||||.:...:||:|:.:
E. coli   577 AHVWFVSQLPKTRSGKMLRRTIQAICEGRDPGDLTTIDDPASLDQIRQAMEE 628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6432	NP_651247.1	PrpE	28..651	CDD:341271	246/629 (39%)
prpE	NP_414869.1	prpE	1..628	CDD:182517	249/635 (39%)