Protein Alignment CG6432 and Aacs

DIOPT Version :10

• Sequence 1: NP_651247.1
• Gene: CG6432 / 42901
• FlyBaseID: FBgn0039184
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_084486.1
• Gene: Aacs / 78894
• MGIID: 1926144
• Length: 672
• Species: Mus musculus
• Alignment Length: 684
• Identity: 159/684 - (23%)
• Similarity: 291/684 - (42%)
• Gaps: 92/684 - (13%)

  Fly    15 SVCGMPVEAHDPLYLKAYRQSVQNPAAFWEEQGNLLDWDRPWEKVLDNSN--PPFTKWYVGGYLN 77
            :.||:.:..::.||..:.|..:...|.||:..|  :.:.|.:::|:|.|.  ....:|:.|..||
Mouse    38 TACGLALGNYNDLYHWSVRSYMDFWAEFWKFSG--IVYSRMYDEVVDTSKGIADVPEWFRGSRLN 100

  Fly    78 ACYNSIDRHILAGRGSNVALIHDSPLTGTLRRVTYQELYDQIVLLAGGLAKLGVVKGDRVVIYMP 142
            ...|.: ||   .....|||.........:.:||::||..|:.|.|..:.|:||.||||||.|:|
Mouse   101 YAENLL-RH---KENDRVALYVAREGREEIVKVTFEELRQQVALFAAAMRKMGVKKGDRVVGYLP 161

  Fly   143 LIPETIIAMLAIVRLGAIHSVVFGGFAARELCSRIEHVEPKLVIASNVGVEPGKVVPYLDILHSA 207
            .....:.||||...:|||.|.....|....:..|...::|||:.:....|..||...:|:.|...
Mouse   162 NSAHAVEAMLAAASIGAIWSSTSPDFGVNGVLDRFSQIQPKLIFSVEAVVYNGKEHGHLEKLQRV 226

  Fly   208 ISMSRWRPPQRNI-----IFRRDNVSPDTTKLDPLTDVLWSDILKMAEGER--PIACVPIEANDP 265
            :   :..|..:.:     :..|:.:  |.:|:.  ..|...|.|....|.:  .:....:..:.|
Mouse   227 V---KGLPDLQRVVLIPYVLPREKI--DISKIP--NSVFLDDFLASGTGAQAPQLEFEQLPFSHP 284

  Fly   266 LYILYTSGTTDKPKGVLRTIGGHLVA-----LVYTLRT-----LYGINPGHTWWAASDMGWVVGH 320
            |:|:::||||..||.::.:.||.|:.     :::...|     ||....|...|     .|:|
Mouse   285 LFIMFSSGTTGAPKCMVHSAGGTLIQHLKEHMLHGNMTSSDILLYYTTVGWMMW-----NWMV-- 342

  Fly   321 SYICYGPLCLGATSVMYEGKPDRTPDPGQYFRIIDQYQVRSIFSVPTSFRVIRRADPDISYGRQY 385
                 ..|..||:.|:|:|.| ..|.|...:.::|:..:..:.:......|:.  :.|:.....:
Mouse   343 -----SALATGASLVLYDGSP-LVPTPNVLWDLVDRIGITILGTGAKWLSVLE--EKDMKPVETH 399

  Fly   386 SMKSLRAIFIAGEHCDYETKSWIEKTFKVPVLNHWWQTETGSAVTATCLGFQQNLSPPTY----- 445
            ::.:|..|...|.....::..::.:..|..||  ......|:.:.:..:|  ||.|.|.|
Mouse   400 NLHTLHTILSTGSPLKAQSYEYVYRCIKSSVL--LGSISGGTDIISCFMG--QNSSIPVYKGEIQ 460

  Fly   446 --STGLPLMGYDVKILKADGSEAQTSELGRIALKLPLPPGNMATLYKNEE---LFRTLYFQKFPG 505
              :.|:.:..:|      :..:|.....|.:....|:|  ...|.:.|:|   .:|..||.||||
Mouse   461 ARNLGMAVEAWD------EEGKAVWGASGELVCTKPIP--CQPTHFWNDENGSKYRKAYFSKFPG 517

  Fly   506 YYDTMD-AGYKDERGYIFVTARDDDVINVAGHRLSTSSLEDAVLRHPDVVDVAVFGVPEATK-GQ 568
            .:...| .....:.|.|.:..|.|..:|..|.|..:|.:.:.|....:|.|...  ||:..: |:
Mouse   518 VWAHGDYCRINPKTGGIIMLGRSDGTLNPNGVRFGSSEIYNIVEAFDEVEDSLC--VPQYNRDGE 580

  Fly   569 VPLCLYIPVENCKKTDAKLSTEIIKLIRDVVGPIAAFR----LVTSVNNLPRTRSGKTMRKAMAD 629
            ..:.|::.:    .:......:::|.|||.:....:.|    |:.....:|.|.:||.:..|:
Mouse   581 ERVVLFLKM----ASGHTFQPDLVKRIRDAIRLGLSARHVPSLILETRGIPYTLNGKKVEVAV-- 639

  Fly   630 FARNERVVLPATIDDASVF-----IEIRRALNQL 658
                ::|:...|::....|     :::.|.:.:|
Mouse   640 ----KQVMAGRTVEHRGAFSNPETLDLYRDIPEL 669

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6432	NP_651247.1	PrpE	28..651	CDD:341271	154/662 (23%)
Aacs	NP_084486.1	ac_ac_CoA_syn	16..671	CDD:273507	159/684 (23%)