Protein Alignment CG6432 and ACSM3

DIOPT Version :9

• Sequence 1: NP_001287502.1
• Gene: CG6432 / 42901
• FlyBaseID: FBgn0039184
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: XP_024306135.1
• Gene: ACSM3 / 6296
• HGNCID: 10522
• Length: 633
• Species: Homo sapiens
• Alignment Length: 599
• Identity: 143/599 - (23%)
• Similarity: 239/599 - (39%)
• Gaps: 128/599 - (21%)

  Fly    63 SNPPFTKWYVGGYLNACYNSIDRHILAGRGSNVALIHDSPLTGTLRRVTYQELYDQIVLLAGGLA 127
            |||.|  |:           |:|:                  |...|.:::||        |.|:
Human    79 SNPAF--WW-----------INRN------------------GEEMRWSFEEL--------GSLS 104

  Fly   128 K---------LGVVKGDRVVIYMPLIPETIIAMLAIVRLGAIHSVVFGG---FAARELCSRIEHV 180
            :         ..:.:||||::.:|.:||..:|.:|.:|.|   :|:..|   ...:::..|::..
Human   105 RKFANILSEACSLQRGDRVILILPRVPEWWLANVACLRTG---TVLIPGTTQLTQKDILYRLQSS 166

  Fly   181 EPKLVIASNVGVEPGKVVPYLDI-------LHSAISMSR-----WR-----------PPQRNIIF 222
            :...:|.::|      :.|.:|.       |||.:.:|.     |.           .|..:.:.
Human   167 KANCIITNDV------LAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMKVFLCHPGWSTVA 225

  Fly   223 RRDNVSPDTTKLDPLTDVLWSDILKMAEGERPIACVPIEANDPLYILYTSGTTDKPKGVLRTIGG 287
            |....:..|:.:..:..:|.|...:.|....  .||..:.|:.:.|.:||||:..||....|...
Human   226 RSWLTATSTSLVQAILSLLSSWDYRHASDSH--TCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSS 288

  Fly   288 HLVALVYTLRTLYGINPGHTWWAASDMGWVVGHSYICYGPLCLGATSVMYEGKPDRTP--DPGQY 350
            ..:.|....|....:.|....|..||.||........:.|...||....:     ..|  :|...
Human   289 FGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACVFTH-----HLPRFEPTSI 348

  Fly   351 FRIIDQYQVRSIFSVPTSFRVIRRADPDISYGRQYSMKSLRAIFIAGEHCDYE-TKSWIEKTFKV 414
            .:.:.:|.:....|.||.:|::  ...||:   .|..|||:....|||....: |:.|..|| .:
Human   349 LQTLSKYPITVFCSAPTVYRML--VQNDIT---SYKFKSLKHCVSAGEPITPDVTEKWRNKT-GL 407

  Fly   415 PVLNHWWQTETGSAVTATCLGFQ-QNLSPPTYSTGLPLMGYDVKILKADGSEAQTSELGRIALK- 477
            .:...:.||||    ...|..|: ..:.|.  |.|.|...:||||:..:|:.....:.|.|.::
Human   408 DIYEGYGQTET----VLICGNFKGMKIKPG--SMGKPSPAFDVKIVDVNGNVLPPGQEGDIGIQV 466

  Fly   478 LPLPPGNMATLY-----KNEELFRTLYFQKFPGYYDTMDAGYKDERGYIFVTARDDDVINVAGHR 537
            ||..|..:.|.|     |.....|       ..:|.|.|.||.|:.||.:..||.||||..:|:|
Human   467 LPNRPFGLFTHYVDNPSKTASTLR-------GNFYITGDRGYMDKDGYFWFVARADDVILSSGYR 524

  Fly   538 LSTSSLEDAVLRHPDVVDVAVFGVPEATKGQVPLCLYIPVENCKKTDAKLSTEIIKLIRDVVGPI 602
            :....:|:|:..||.|.:.||...|:..:|:|.....:...:.|..|.:   ::||.|::.|
Human   525 IGPFEVENALNEHPSVAESAVVSSPDPIRGEVVKAFVVLNPDYKSHDQE---QLIKEIQEHV--- 583

  Fly   603 AAFRLVTSVNNLPR 616
               :..|:....||
Human   584 ---KKTTAPYKYPR 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6432	NP_001287502.1	prpE	28..657	CDD:182517	143/599 (24%)
		PrpE	37..651	CDD:213314	143/599 (24%)
ACSM3	XP_024306135.1	AFD_class_I	54..596	CDD:327384	143/599 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0365
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810