Protein Alignment CG6432 and ACSM5

DIOPT Version :9

• Sequence 1: NP_001287502.1
• Gene: CG6432 / 42901
• FlyBaseID: FBgn0039184
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_001311301.1
• Gene: ACSM5 / 54988
• HGNCID: 26060
• Length: 582
• Species: Homo sapiens
• Alignment Length: 632
• Identity: 144/632 - (22%)
• Similarity: 250/632 - (39%)
• Gaps: 144/632 - (22%)

  Fly    13 SESVCG-------MPVEAHDPLYLKAYRQSVQNPAAFWE----------EQGN----LLD-WDRP 55
            |.:.||       :||.              |...|.||          |..|    :|| |.|.
Human    16 SRAFCGSHGKPAPLPVP--------------QKIVATWEAISLGRQLVPEYFNFAHDVLDVWSRL 66

  Fly    56 WEKVLDNSNPPFTKWYVGGYLNACYNSIDRHILAGRGSNVALIHDSPLTGTLRRVTYQELYDQ-- 118
            .|......||.|  |:|.|                             ||...:.:::||..|
Human    67 EEAGHRPPNPAF--WWVNG-----------------------------TGAEIKWSFEELGKQSR 100

  Fly   119 -IVLLAGGLAKLGVVKGDRVVIYMPLIPETIIAMLAIVRLGAIHSVVFGGFAARELCSRIEHVEP 182
             ...:.||..  |:..|||:::.:|.:||..:..:|.:|.|.:..........::|..|::....
Human   101 KAANVLGGAC--GLQPGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGVTQLTEKDLKYRLQASRA 163

  Fly   183 KLVIASNVGVEPGKVVPYLDILHSAISMSRWRPPQRNIIFRRDNVSPDTTKLDPLTDVLW---SD 244
            |.:|.|:      .:.|.:|      ::|...|..:..:...|:..|.           |   .:
Human   164 KSIITSD------SLAPRVD------AISAECPSLQTKLLVSDSSRPG-----------WLNFRE 205

  Fly   245 ILKMAEGERPIACVPIEANDPLYILYTSGTTDKPKGVLRTIGGHLVALVYTLRTLYGINPGHTWW 309
            :|:.|..|.  .|:..::.|||.|.:|||||..||.|..:...:.:..|.:.|....:.....:|
Human   206 LLREASTEH--NCMRTKSRDPLAIYFTSGTTGAPKMVEHSQSSYGLGFVASGRRWVALTESDIFW 268

  Fly   310 AASDMGWVVGHSYICYGPLCLGATSVMYEGKPDRTP--DPGQYFRIIDQYQVRSIFSVPTSFRVI 372
            ..:|.|||.. ::..:.....|:...::|     .|  |.......:.::.:.::..|||.||::
Human   269 NTTDTGWVKA-AWTLFSAWPNGSCIFVHE-----LPRVDAKVILNTLSKFPITTLCCVPTIFRLL 327

  Fly   373 RRADPDISYGRQYSMKSLRAIFIAGEHCDYETK-SWIEKTFKVPVLNHWWQTET--------GSA 428
            .:.|.     .:|..:|||.....||..:.:.: .|..:| .|.:...:.|:||        |..
Human   328 VQEDL-----TRYQFQSLRHCLTGGEALNPDVREKWKHQT-GVELYEGYGQSETVVICANPKGMK 386

  Fly   429 VTATCLGFQQNLSPPTYSTGLPLMGYDVKILKADGSEAQTSELGRIALKL-PLPPGNMATLY-KN 491
            :.:..:|   ..|||          |||:|:..:|:.....|.|.:|::: |..|......| .|
Human   387 IKSGSMG---KASPP----------YDVQIVDDEGNVLPPGEEGNVAVRIRPTRPFCFFNCYLDN 438

  Fly   492 EELFRTLYFQKFPGYYDTMDAGYKDERGYIFVTARDDDVINVAGHRLSTSSLEDAVLRHPDVVDV 556
            .|  :|...:: ..:|.|.|....|:.||.:...|:|||||.:.:|:....:|.|:..||.|::.
Human   439 PE--KTAASEQ-GDFYITGDRARMDKDGYFWFMGRNDDVINSSSYRIGPVEVESALAEHPAVLES 500

  Fly   557 AVFGVPEATKGQVPLCLYI--PVENCKKTDAKLSTEIIKLIRDVVGP 601
            ||...|:..:|:|.....:  |..:....:| |:.|:.:.::.|..|
Human   501 AVVSSPDPIRGEVVKAFIVLTPAYSSHDPEA-LTRELQEHVKRVTAP 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6432	NP_001287502.1	prpE	28..657	CDD:182517	139/610 (23%)
		PrpE	37..651	CDD:213314	139/601 (23%)
ACSM5	NP_001311301.1	Acs	49..552	CDD:223442	135/585 (23%)
		AFD_class_I	49..552	CDD:302604	135/585 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0365
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810