Protein Alignment CG6432 and ACSM2B

DIOPT Version :10

• Sequence 1: NP_651247.1
• Gene: CG6432 / 42901
• FlyBaseID: FBgn0039184
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_872423.3
• Gene: ACSM2B / 348158
• HGNCID: 30931
• Length: 577
• Species: Homo sapiens
• Alignment Length: 542
• Identity: 129/542 - (23%)
• Similarity: 217/542 - (40%)
• Gaps: 105/542 - (19%)

  Fly   121 LLAGGLAKLGVVKGDRVVIYMPLIPETIIAMLAIVRLGAIHSVVFGGFAARELCSRIEHVEPKLV 185
            :|:|.   .|:.:||||.:.:|.:||..:.:|..:|.|.|.........:.::..|::..:.|.:
Human    96 ILSGA---CGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAI 157

  Fly   186 IASNVGVEPGKVVPYLDILHSAISMSRWRPPQRNIIFRRDNVSPDTTKLDPLTDVLWSDILKMA- 249
            :|.:      :|:..:|.:.|..       |...|.......|.|.          |.:..|:.
Human   158 VAGD------EVIQEVDTVASEC-------PSLRIKLLVSEKSCDG----------WLNFKKLLN 199

  Fly   250 EGERPIACVPIEANDPLYILYTSGTTDKPKGVLRTIGGHLVALV---------YTLRTLYGINPG 305
            |......||...:.:...|.:||||:..||     :..|..:.:         :|     |:...
Human   200 EASTTHHCVETGSQEASAIYFTSGTSGLPK-----MAEHSYSSLGLKAKMDAGWT-----GLQAS 254

  Fly   306 HTWWAASDMGWVVGHSYICYGPL----CLGATSVMYEGKPDRTP--DPGQYFRIIDQYQVRSIFS 364
            ...|..||.||::.    ..|.|    .|||.:.::     ..|  ||....:.:..|.::|:..
Human   255 DIMWTISDTGWILN----ILGSLLESWTLGACTFVH-----LLPKFDPLVILKTLSSYPIKSMMG 310

  Fly   365 VPTSFRVIRRADPDISYGRQYSMKSLRAIFIAGEHCDYET-KSWIEKTFKVPVLNHWWQTETGSA 428
            .|..:|::.:.|..     .|....|:.....||....|| ::|..:| .:.:...:.|||||
Human   311 APIVYRMLLQQDLS-----SYKFPHLQNCLAGGESLLPETLENWRAQT-GLDIREFYGQTETG-- 367

  Fly   429 VTATCLGFQQNLSPPTYSTGLPLMGYDVKILKADGSEAQTSELGRIALKLPLPPGNMATLYKNEE 493
              .||:..:.....|.| .|.....|||:::...|:              .||||....:....:
Human   368 --LTCMVSKTMKIKPGY-MGTAASCYDVQVIDDKGN--------------VLPPGTEGDIGIRVK 415

  Fly   494 LFRTLYFQKFPGYYDTM---------------DAGYKDERGYIFVTARDDDVINVAGHRLSTSSL 543
            ..|.:..  |.||.:..               |.|.|||.||.....|.||:||.:|:|:..|.:
Human   416 PIRPIGI--FSGYVENPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEV 478

  Fly   544 EDAVLRHPDVVDVAVFGVPEATKGQVPLCLYIPVENCKKTD-AKLSTEIIKLIRDVVGPIAAFRL 607
            |:|:::||.||:.||...|:..:|:|.....|........| .:|:.|:.:.::.|..|....|.
Human   479 ENALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSHDPEQLTKELQQHVKSVTAPYKYPRK 543

  Fly   608 VTSVNNLPRTRSGKTMRKAMAD 629
            :..|.|||:|.:||..|..:.|
Human   544 IEFVLNLPKTVTGKIQRTKLRD 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6432	NP_651247.1	PrpE	28..651	CDD:341271	129/542 (24%)
ACSM2B	NP_872423.3	Adenylate forming domain, Class I superfamily	40..568	CDD:473059	129/542 (24%)