Protein Alignment CG6432 and ACSM4

DIOPT Version :10

• Sequence 1: NP_651247.1
• Gene: CG6432 / 42901
• FlyBaseID: FBgn0039184
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_001073923.1
• Gene: ACSM4 / 341392
• HGNCID: 32016
• Length: 580
• Species: Homo sapiens
• Alignment Length: 622
• Identity: 152/622 - (24%)
• Similarity: 245/622 - (39%)
• Gaps: 162/622 - (26%)

  Fly    53 DRPWEKVLDNSNPPFTKWYVGGYLNACYNSIDRHILAGRGSNVALIHDSPLTGTLRRVTYQELYD 117
            :||       :||..  |:|.                |:|..|             :.:::||..
Human    70 ERP-------ANPAL--WWVN----------------GKGDEV-------------KWSFRELGS 96

  Fly   118 QIVLLAGGLAK-LGVVKGDRVVIYMPLIPETIIAMLAIVRLGAIHSVVFGGFAARELCSRIEHVE 181
            .....|..|.| .|:.:|||:.:.:|.|||..:..:|.:|.|.|.........|:::..|:...:
Human    97 LSRKAANVLTKPCGLQRGDRLAVILPRIPEWWLVNVACIRTGIIFMPGTIQLTAKDILYRLRASK 161

  Fly   182 PKLVIASNVGVEPGKVVPYLDILHSAISMSRWRPPQRNIIFRRDNVSPD-TTKL--DPLTDVLW- 242
            .|.::||.      :|.|.::                :|:..    .|| .|||  .|.:...|
Human   162 AKCIVASE------EVAPAVE----------------SIVLE----CPDLKTKLLVSPQSWNGWL 200

  Fly   243 --SDILKMAEGERPIACVPIEANDPLYILYTSGTTDKPKGVLRTIGGHLVALVYTLRTLYGINPG 305
              .::.:.|..|.  :||...:.:|:.|.:|||||..||....:...  :.:.:||       .|
Human   201 SFQELFQFASEEH--SCVETGSQEPMTIYFTSGTTGFPKMAQHSQSS--LGIGFTL-------CG 254

  Fly   306 HTW---------WAASDMGWV------VGHSYICYGPLCLGATSVMYEGKPDRTPDPGQYFRIID 355
            ..|         |..||.|||      |..|::|      ||...::.....   |...:...:.
Human   255 RYWLDLKSSDIIWNMSDTGWVKAAIGSVFSSWLC------GACVFVHRMAQF---DTDTFLDTLT 310

  Fly   356 QYQVRSIFSVPTSFRVIRRADPDISYGRQYSMKSLRAIFIAGEHCDYET-KSWIEKTFKVPVLNH 419
            .|.:.::.|.||.:|::.:.|.     ::|..||||.....||..:.|. :.|..:| .:.:...
Human   311 TYPITTLCSPPTVYRMLVQKDL-----KRYKFKSLRHCLTGGEPLNPEVLEQWRVQT-GLELYEG 369

  Fly   420 WWQTETGSAVTATCLGFQQNLSPPTYSTGLPLMGYDVKILKADGSEAQTSELGRIALKL-PLPPG 483
            :.|||.| .:.|...|  |.:.|.  |.|..::.|||:|:..:|:.....:.|.|||:| |..|
Human   370 YGQTEVG-MICANQKG--QEIKPG--SMGKGMLPYDVQIIDENGNVLPPGKEGEIALRLKPTRP- 428

  Fly   484 NMATLYKNEELFRTLYFQKF------------PGYYDTMDAGYKDERGYIFVTARDDDVINVAGH 536
                         ..:|.|:            ..:|.|.|.|..|..||.:...|.||||..:|:
Human   429 -------------FCFFSKYVDNPQKTAATIRGDFYVTGDRGVMDSDGYFWFVGRADDVIISSGY 480

  Fly   537 RLSTSSLEDAVLRHPDVVDVAVFGVPEATKGQV---------PLCLYIPVENCKKTDAKLSTEII 592
            |:....:|.|::.||.||:.||...|:..:|:|         |...|.|        .||:.|:.
Human   481 RIGPFEVESALIEHPAVVESAVVSSPDQIRGEVVKAFVVLAAPFKSYNP--------EKLTLELQ 537

  Fly   593 KLIRDVVGPIAAFRLVTSVNNLPRTRSGKTMRKAMAD 629
            ..::....|....|.|..|..||:|.:||..|..:.|
Human   538 DHVKKSTAPYKYPRKVEFVQELPKTITGKIKRNVLRD 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6432	NP_651247.1	PrpE	28..651	CDD:341271	152/622 (24%)
ACSM4	NP_001073923.1	MACS_euk	48..577	CDD:341251	152/622 (24%)