Protein Alignment CG6432 and sur-5

DIOPT Version :10

• Sequence 1: NP_651247.1
• Gene: CG6432 / 42901
• FlyBaseID: FBgn0039184
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_509229.1
• Gene: sur-5 / 180992
• WormBaseID: WBGene00006351
• Length: 700
• Species: Caenorhabditis elegans
• Alignment Length: 676
• Identity: 139/676 - (20%)
• Similarity: 270/676 - (39%)
• Gaps: 103/676 - (15%)

  Fly    28 YLKAYRQSVQNPAAFWEEQGNLLD--WDRPWEKVLD-----NSNPPFTKWYVGGYLNACYNSIDR 85
            |.:.:|.:..|...|||:...|.|  ..:.:.:|:|     |..|   :|:.|..||...|.|:|
 Worm    76 YREFHRFTCDNYGIFWEDLLKLSDVKLHQNYNQVIDHNLKINERP---RWFNGATLNYTENVIER 137

  Fly    86 HILAGRGSNVALIHDSPLTGTLRRVTYQELYDQIVLLAGGLAKLGVVKGDRVVIYMPLIPETIIA 150
                |..:::|:::.| :..|:...||..|...:..:|..|...|:..||.|..::|...:|::|
 Worm   138 ----GTATDIAVLNAS-IEETVTEYTYDNLRKDVYRIATSLRNYGIGPGDTVCGFVPNTYDTLVA 197

  Fly   151 MLAIVRLGAIHSVVFGGFAARELCSRIEHVEPKLVIASNVGVEPGKVVPYLDILHSAISMSRWRP 215
            :.|...:||........|....:..|...|.||::...|......|::...|.::..:   :..|
 Worm   198 VFATAAVGAAWCSASVDFGPAGVLDRFRQVHPKVLFTVNHVTYKKKLIDQTDKINEIV---KELP 259

  Fly   216 PQRNIIFRR--DNVSPDTTKLD-------------PLTDVLWSDILKMAEGERPIACVPIEANDP 265
            ....|:...  .:|..|.||.:             |:.||:           .|....|:..:||
 Worm   260 TLEKIVVSDTFTSVKFDATKYNQSDKFSSLEEFKTPIADVV-----------LPFVYTPVPFSDP 313

  Fly   266 LYILYTSGTTDKPKGVLRTIGGHLVALVYTLRTLYGINPGH-TWWAASDMGWVVGHSYICYGPLC 329
            |:::::||||..||.::.|:||.|:..:.. ..:.|.:..| ..:..:..||::.:..|.:  |.
 Worm   314 LFVMFSSGTTGIPKAMVHTVGGTLLKHIEE-HLVQGDSKKHDRMFFYTTCGWMMYNWMISF--LY 375

  Fly   330 LGATSVMYEGKPDRTPDP---------------GQYFRIIDQYQVRSIFSVPTSFRVIRRADPDI 379
            ...:.|:::..| ..||.               |...::.|:|           .|:      .|
 Worm   376 SKGSVVLFDECP-LAPDTHIIMKIAAKTQSTMIGMGAKLYDEY-----------LRL------QI 422

  Fly   380 SYGRQYSMKSLRAIFIAGEHCDYETKSWIEKTFKVP---VLNHWWQTETGSAVTATCLGFQQNLS 441
            .:...|.:..:..::..|.....|..::| .|:..|   :.:    ...|:.:....:|..::||
 Worm   423 PFNTLYDLSKIHTVYSTGSPLKKECFAYI-NTYIAPGALIAS----ISGGTDIIGCFVGGIKSLS 482

  Fly   442 PPTYSTGLPLMGYDVKILK-ADGSEAQTSELGRIALKLPLPPGNMATLYKNE---ELFRTLYFQK 502
            ..........:|.|:|... .|.....:.|.|.:....|.|  :|.:.:.|:   :.:|..||.:
 Worm   483 ITPGECQCLFLGMDIKSFNYMDEEIINSDEQGELVCVTPFP--SMPSHFLNDTDGKKYRDAYFAR 545

  Fly   503 FPGYYDTMD-AGYKDERGYIFVTARDDDVINVAGHRLSTSSLEDAVLRHPDVVDVAVFG--VPEA 564
            ...::...| .......|.:.:..|.|..:|..|.|:.|:.:...|.:.|.:.|..|.|  |.|.
 Worm   546 LEPFWAHGDFVRVNHSTGGVEMLGRSDATLNRGGVRIGTAEIYSVVEKIPHIADCIVAGRLVEEG 610

  Fly   565 TKGQVPLCLYIPVENCKKTDAKLSTEIIKLIRDVVGPIAAFRLVTSVNNLPRTRSGKTMRKAMAD 629
            ...:|  .|::.:...::....:...|:..:|:.:.|......:.:|:::|.|.|||.:..|:..
 Worm   611 MDEEV--LLFVKMVPGQELTHSIQAAIVSKLRNDMSPRHVPNKIYAVDDIPYTSSGKKVEVAVKQ 673

  Fly   630 FARNERVVLPATI---DDASVFIEIR 652
            ....:.|...::|   :....|::.|
 Worm   674 IVSGKAVQKASSIRNPESLDHFVQYR 699

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6432	NP_651247.1	PrpE	28..651	CDD:341271	138/673 (21%)
sur-5	NP_509229.1	AACS	62..695	CDD:341265	137/670 (20%)