Protein Alignment CG6432 and ACSM1

DIOPT Version :9

• Sequence 1: NP_001287502.1
• Gene: CG6432 / 42901
• FlyBaseID: FBgn0039184
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_001305819.1
• Gene: ACSM1 / 116285
• HGNCID: 18049
• Length: 577
• Species: Homo sapiens
• Alignment Length: 612
• Identity: 142/612 - (23%)
• Similarity: 248/612 - (40%)
• Gaps: 130/612 - (21%)

  Fly    49 LLD-WDRPWEKVLDNSNPPFTKWYVGGYLNACYNSIDRHILAGRGSNVALIHDSPLTGTLRRVTY 112
            :|| |.:..::.....||.|  |:|.                |:|..|             :.::
Human    55 VLDYWAQKEKEGKRGPNPAF--WWVN----------------GQGDEV-------------KWSF 88

  Fly   113 QELYDQIVLLAGGLAK-LGVVKGDRVVIYMPLIPETIIAMLAIVRLGAIHSVVFGGFAARELCSR 176
            :|:.|....:|....: .|:.:||.:.:.:|.:||..:..:..:|.|.|.........|:::..|
Human    89 REMGDLTRRVANVFTQTCGLQQGDHLALMLPRVPEWWLVAVGCMRTGIIFIPATILLKAKDILYR 153

  Fly   177 IEHVEPKLVIASNVGVEPGKVVPYLDILHSAISMSRWRPPQRNIIFRRDNVSPDTTKLDPLTDVL 241
            ::..:.|.::.             :|.|.|.:                |:::.....|.  |.:|
Human   154 LQLSKAKGIVT-------------IDALASEV----------------DSIASQCPSLK--TKLL 187

  Fly   242 WSD-----------ILKMAEGERPIACVPIEANDPLYILYTSGTTDKPKGVLRTIGGHLVALVYT 295
            .||           ::|.|..|.  .||..:..||:.|.:|||||..||....:.|..|......
Human   188 VSDHSREGWLDFRSLVKSASPEH--TCVKSKTLDPMVIFFTSGTTGFPKMAKHSHGLALQPSFPG 250

  Fly   296 LRTLYGINPGHTWWAASDMGWVVGHSYICYGPLCLGATSVMYEGKPDRTP--DPGQYFRIIDQYQ 358
            .|.|..:......|..||.||:|...:....|...|.|..::     ..|  |.....:.:.:|.
Human   251 SRKLRSLKTSDVSWCLSDSGWIVATIWTLVEPWTAGCTVFIH-----HLPQFDTKVIIQTLLKYP 310

  Fly   359 VRSIFSVPTSFRVIRRADPDISYGRQYSMKSLRAIFIAGEHC--------DYETKSWIEKTFKVP 415
            :...:.|.:.:|:|.:.|          ..|:|  |.|.|||        ..:.:.|..:| .:.
Human   311 INHFWGVSSIYRMILQQD----------FTSIR--FPALEHCYTGGEVVLPKDQEEWKRRT-GLL 362

  Fly   416 VLNHWWQTETGSAVTATCL------GFQQNLSPPTYSTGLPLMGYDVKILKADGSEAQTSELGRI 474
            :..::.|:||| .:.||..      ||....:||          |||:::...||....:..|.|
Human   363 LYENYGQSETG-LICATYWGMKIKPGFMGKATPP----------YDVQVIDDKGSILPPNTEGNI 416

  Fly   475 ALKL-PLPPGNMATLYKN--EELFRTLYFQKFPGYYDTMDAGYKDERGYIFVTARDDDVINVAGH 536
            .::: |:.|.::...|:.  |:..:.    :...:|:|.|.|..||.|||....|.||:||.:|:
Human   417 GIRIKPVRPVSLFMCYEGDPEKTAKV----ECGDFYNTGDRGKMDEEGYICFLGRSDDIINASGY 477

  Fly   537 RLSTSSLEDAVLRHPDVVDVAVFGVPEATKGQVPLCLYIPVENCKKTDA-KLSTEIIKLIRDVVG 600
            |:..:.:|.|::.||.|.:.||.|.|:..:|:|.....:........|. :|:.|:.:.::.|..
Human   478 RIGPAEVESALVEHPAVAESAVVGSPDPIRGEVVKAFIVLTPQFLSHDKDQLTKELQQHVKSVTA 542

  Fly   601 PIAAFRLVTSVNNLPRTRSGKTMRKAM 627
            |....|.|..|:.||:|.:||..||.:
Human   543 PYKYPRKVEFVSELPKTITGKIERKEL 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6432	NP_001287502.1	prpE	28..657	CDD:182517	142/612 (23%)
		PrpE	37..651	CDD:213314	142/612 (23%)
ACSM1	NP_001305819.1	MACS_euk	45..574	CDD:341251	142/612 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0365
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810