Protein Alignment ASCL1 and Fer3

DIOPT Version :10

• Sequence 1: NP_004307.2
• Gene: ASCL1 / 429
• HGNCID: 738
• Length: 236
• Species: Homo sapiens
• Sequence 2: NP_524322.1
• Gene: Fer3 / 41411
• FlyBaseID: FBgn0037937
• Length: 195
• Species: Drosophila melanogaster
• Alignment Length: 221
• Identity: 56/221 - (25%)
• Similarity: 88/221 - (39%)
• Gaps: 70/221 - (31%)

Human    13 GQQPQPQPQQPFLPPAACFFATAAAAAAAAAAAAAQSAQQQQQQQQQQQQAPQLRPAADGQPSGG 77
            ||:..|.|..|:....|.|..|..:.               .|:.|.....|| ||:.:|:.:|
  Fly    23 GQEAPPPPIVPYQELIAGFPCTDLSL---------------WQRSQVTPLVPQ-RPSTNGRANG- 70

Human    78 GHKSAPKQVKRQRSSSPELMRCKRRLNFSGFGYSLPQQQPAAVARR---NERERNRVKLVNLGFA 139
                          ||....:.:||:              |::|:|   |.|||.|:..:|..|.
  Fly    71 --------------SSSSSKKTRRRV--------------ASMAQRRAANIRERRRMFNLNEAFD 107

Human   140 TLREHVPNGAANKKMSKVETLRSAVEYIRALQQLL------------DEHDAVSAAFQAGVLSPT 192
            .||..||..|..|::|::||||.|:.||..:.:||            |.:.:::...||.  .|.
  Fly   108 KLRRKVPTFAYEKRLSRIETLRLAITYIGFMAELLSGTPSNSHKSRSDVYGSMNGHHQAP--PPA 170

Human   193 ISPNYSNDLNSMAGSPVSSYSSDEGS 218
            |.|::.:        |.::|..|..|
  Fly   171 IHPHHLH--------PAAAYQRDFAS 188

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ASCL1	NP_004307.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..26		5/12 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..98		10/55 (18%)
		bHLH_TS_ASCL1_Mash1	115..185	CDD:381585	27/84 (32%)
Fer3	NP_524322.1	bHLH_TS_FERD3L_NATO3	79..142	CDD:381421	26/76 (34%)