Protein Alignment ASCL1 and Oli

DIOPT Version :10

• Sequence 1: NP_004307.2
• Gene: ASCL1 / 429
• HGNCID: 738
• Length: 236
• Species: Homo sapiens
• Sequence 2: NP_523592.1
• Gene: Oli / 35066
• FlyBaseID: FBgn0032651
• Length: 232
• Species: Drosophila melanogaster
• Alignment Length: 183
• Identity: 49/183 - (26%)
• Similarity: 65/183 - (35%)
• Gaps: 55/183 - (30%)

Human    11 GAGQQP-----QPQPQQPFLPPAACFFATAAAAAAAAAAAAAQSAQQQQQQQQQQQQAPQLRPAA 70
            |..|||     :|.|..|..|    ...||||.||.|.:....:.                 ..:
  Fly    64 GMSQQPPTDENKPGPSAPEKP----LSPTAAAIAAIAISGGTTTV-----------------AVS 107

Human    71 DGQPSGGGHKSAPKQVKRQRSSSPELMRCKRRLNFSGFGYSLPQQQPAAVARRNERERNRVKLVN 135
            .|..||.|..|. ||..||..:.        |||.                  |.|||.|:..:|
  Fly   108 SGGASGSGSNSG-KQKNRQGKTV--------RLNI------------------NARERRRMHDLN 145

Human   136 LGFATLREHVP--NGAANKKMSKVETLRSAVEYIRALQQLLDEHDAVSAAFQA 186
            .....||..:|  :..:.:|:||:.||..|..||...|..|:|...:.|..|:
  Fly   146 DALDELRSVIPYAHSPSVRKLSKIATLLLAKNYILMQQNALEELRRLLAYIQS 198

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ASCL1	NP_004307.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..26		7/19 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..98		10/55 (18%)
		bHLH_TS_ASCL1_Mash1	115..185	CDD:381585	21/71 (30%)
Oli	NP_523592.1	bHLH_TS_bHLHe22_bHLHb5	129..198	CDD:381524	24/94 (26%)