DRSC/TRiP Functional Genomics Resources

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Protein Alignment ASCL1 and Hand

DIOPT Version :9

Sequence 1:NP_004307.2 Gene:ASCL1 / 429 HGNCID:738 Length:236 Species:Homo sapiens
Sequence 2:NP_609370.2 Gene:Hand / 34379 FlyBaseID:FBgn0032209 Length:174 Species:Drosophila melanogaster


Alignment Length:99 Identity:33/99 - (33%)
Similarity:51/99 - (51%) Gaps:16/99 - (16%)


- Green bases have known domain annotations that are detailed below.


Human    80 KSAPKQVKRQRSSSPELMRCKRRLNFSGFGYSLPQQQPAAVARR---NERERNRVKLVNLGFATL 141
            |.:..||::|            ..|.|..|| :|......|.:|   |::||.|.:.:|..|:.|
  Fly    30 KHSESQVQQQ------------IYNTSHLGY-VPTSNTRIVKKRNTANKKERRRTQSINNAFSYL 81

Human   142 REHVPNGAANKKMSKVETLRSAVEYIRALQQLLD 175
            ||.:||...:.|:||::||:.|:.||..|..:||
  Fly    82 REKIPNVPTDTKLSKIKTLKLAILYINYLVNVLD 115

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ASCL1NP_004307.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..26
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 42..98 4/17 (24%)
bHLH_TS_ASCL1_Mash1 115..185 CDD:381585 24/64 (38%)
HandNP_609370.2 HLH 59..110 CDD:278439 20/50 (40%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4029
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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