DRSC/TRiP Functional Genomics Resources

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Protein Alignment ASCL1 and HLH3B

DIOPT Version :10

Sequence 1:NP_004307.2 Gene:ASCL1 / 429 HGNCID:738 Length:236 Species:Homo sapiens
Sequence 2:NP_525055.1 Gene:HLH3B / 31249 FlyBaseID:FBgn0011276 Length:376 Species:Drosophila melanogaster


Alignment Length:84 Identity:35/84 - (41%)
Similarity:49/84 - (58%) Gaps:9/84 - (10%)


- Green bases have known domain annotations that are detailed below.


Human   124 NERERNRVKLVNLGFATLREHVPNGAANKKMSKVETLRSAVEYIRALQQLLD--EHDAVSAAFQA 186
            |.|||.|.:.|:..||.||:.||....:||:||.|.||||::||:.|..:|:  :..|.|...:|
  Fly   171 NTRERWRQQNVSGAFAELRKLVPTHPPDKKLSKNEILRSAIKYIKLLTGILEWQQRQAPSHPIRA 235

Human   187 GVLSPTISPNYSNDLNSMA 205
                 .:.|| :|| |.||
  Fly   236 -----QMEPN-NND-NRMA 247

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ASCL1NP_004307.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..26
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 42..98
bHLH_TS_ASCL1_Mash1 115..185 CDD:381585 27/62 (44%)
HLH3BNP_525055.1 bHLH_TS_dHLH3B_like 166..225 CDD:381551 25/53 (47%)
Blue background indicates that the domain is not in the aligned region.

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