DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nab2 and AT3G12640

DIOPT Version :9

Sequence 1:	NP_651243.1	Gene:	Nab2 / 42897	FlyBaseID:	FBgn0028471	Length:	1004	Species:	Drosophila melanogaster
Sequence 2:	NP_001325953.1	Gene:	AT3G12640 / 820444	AraportID:	AT3G12640	Length:	662	Species:	Arabidopsis thaliana

Alignment Length:	820	Identity:	171/820 - (20%)
Similarity:	286/820 - (34%)	Gaps:	248/820 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 KMRSAVKAKLLELGTGGSAGFIDDELPDYVMVMVANKRTKQQMNAELNLFLGDQTDLFVTWLHEV 76
            |::..||.||.|.    ...:.||.|.:||:|::.|.|.|::.|.||.:||||.:|.||.||.:.
plant    23 KLKEMVKDKLKEY----MGDYTDDILVEYVIVLLRNGRRKEEANNELKIFLGDDSDSFVAWLWDH 83

  Fly    77 L---------QKLQEVTLPTSSASSKKRKS---RGQEKDKKGSKKDKRPHRKSGDELSEPQPSSS 129
            |         ..::..|:.:|..||.:.|:   ...|.||  .:.||....:.|.:......:.|
plant    84 LAESVDEYFSSNVEGTTIKSSLISSHEDKALVPLDSEYDK--GRSDKSNGARRGRQWRSQPTNVS 146

  Fly   130 DAMPIVSSITDVFAEELLEKAKKTMDIDLSAKDEILHKKKNRKSIEDEDASANRALDVPAVSEII 194
            :..|::||  :|......||           ||   ||.::.|......|.:.|...
plant   147 EIPPLLSS--EVHKIHNYEK-----------KD---HKHRHNKRSPSPQAQSQRKRS-------- 187

  Fly   195 STTIGVNRQKDLAELAEIQKKIHAAKKHLRQIGEIGDESDEYDEDLLNLSAREESVDQEPEEDPP 259
            .|....|.|::..  .::.:::  .:..:|....|...::...|..|.......|...:...||.
plant   188 RTDDSRNEQREAK--PDVSRRL--LQFAVRDALAISRPANSSTESSLKRLRSVVSTSTQNSSDPD 248

  Fly   260 KLEAPPRKAKSPI-IFNRREKTPEKRPEAEPEIDSRQEEAEEKSPKKDSSADKAKEDRSERRSVH 323
                |.||.:|.. :.|             |.....:..||        :|:.||:.:| .|||.
plant   249 ----PARKIRSVARVVN-------------PMATVMKAVAE--------AAEDAKKPKS-GRSVF 287

  Fly   324 DRL----GSKA---------QTPADRSQRNQKELYVPTHRRRSEPEATKERSQRERTRERRSS-- 373
            ||:    ||:.         .:|.|...||..:              .:|..|.:.|:...::
plant   288 DRISHSTGSETLDQNMVLGEVSPKDEESRNFSQ--------------GQEAVQLQYTQSLANNGV 338

  Fly   374 ---RDTSRDTNRNQRQRRSPSPEAPSTKQRIVSQVIVAVNKPPEPSDDEDMAEKPVNSVIKVKPR 435
               ..|:.||..|        |:..|.:.|:.|.|.|:     .||   ......:|:
plant   339 YFENMTTNDTGLN--------PDFSSDRGRLGSSVNVS-----HPS---TYLGNRINN------- 380

  Fly   436 PNVSPRRQACKNLLLRAVADAQRSTILAKTSTQKEDEDVGKIISSLGKRKSEDKNDQIRKRNRER 500
            ||         :|..|.|.|::|                           .:..|.|.|......
plant   381 PN---------SLQHRLVDDSKR---------------------------VKGTNYQNRLPEVAT 409

  Fly   501 KRRKRSAQGNELFRRTTRELVVNVTQRDGKRERRSNERRAEIKVVEEEYTPSLMTEGVETYVPQL 565
            |.:..|..||....:|                         :|:.|:...|.:   |::.|
plant   410 KHKTASFSGNIDTGKT-------------------------VKLEEQRKIPDV---GLQRY---- 442

  Fly   566 LTNVDELDLHISSHDEPSPNSGALKTQFVVTLNGDKALGGKNVKGGASRKRPSNSRKRSTSPVST 630
               :||..| :||.     .:..|.||.::   || .:|..|||..||.|..|.:.|.....:||
plant   443 ---MDEGRL-VSSE-----ATTQLSTQKIL---GD-TIGNGNVKPAASVKEESTTNKSVPGTLST 494

  Fly   631 PQ---------VSSSNIEPTSTTVDKRRRSNRD----RSF---SPSPRQSSGSPSLPTTR----- 674
            .:         :..:|:...:|.....|..|:.    ::|   .|:..|.|||..:..||
plant   495 TRPLEDASSRTIFVANVHFGATKDSLSRHFNKFGEVLKAFIVTDPATGQPSGSAYIEFTRKEAAE 559

  Fly   675 -SINRNEVRRQPQEIKKIIIKNDTDEDDE-------MHGSPKKRSPNKRQPAAANGHKDNKDKGK 731
             :::.:......:.:|  |:|....::.|       ..|....|:|:..:..|..|....:..|:
plant   560 NALSLDGTSFMSRILK--IVKGSNGQNQEAASSMSWSRGGRFTRAPSYFRGGAVRGRSVVRGGGR 622

  Fly   732 --------IEEGSTTPPLPAKPKARAEKKASSKEKSVRSN 763
                    .:.|:.....|...::....:|.||...|.::
plant   623 SMQWKRDSADTGNNNNVAPNNARSLTYVRAESKSDGVAND 662

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nab2	NP_651243.1	zf-CCCH_2	878..896	CDD:291282
AT3G12640	NP_001325953.1	PWI	23..86	CDD:413375	28/66 (42%)
		SF-CC1	<450..>596	CDD:273721	34/156 (22%)
		RRM	505..576	CDD:214636	13/72 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3702
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2298
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004764
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR14738
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.050