DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nab2 and AT2G24350

DIOPT Version :9

Sequence 1:	NP_651243.1	Gene:	Nab2 / 42897	FlyBaseID:	FBgn0028471	Length:	1004	Species:	Drosophila melanogaster
Sequence 2:	NP_180012.2	Gene:	AT2G24350 / 816971	AraportID:	AT2G24350	Length:	537	Species:	Arabidopsis thaliana

Alignment Length:	555	Identity:	117/555 - (21%)
Similarity:	208/555 - (37%)	Gaps:	157/555 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 SEIGQKMRSAVKAKLLELGTGGSAGFID---DELPDYVMVMVANKRTKQQMNAELNLFLGDQTDL 68
            ||...::::.:...|        ..|.|   |:|.:||.|:|.|.::::|.:.:|..||.:|:..
plant    16 SESASRLKTIISDML--------PRFTDDYSDDLSEYVTVLVCNGKSQRQASEDLEAFLKEQSWK 72

  Fly    69 FVTWLHEVLQKLQEVTLPTSSASSKKRKSRGQEKD---KKG--SKKDKRPHRKSGDELSEPQPSS 128
            ||..|.|:|.|...   .::|||..|........|   |:|  |:|......|:.|.
plant    73 FVVCLWELLVKYFS---QSNSASGPKTDVDFGSNDTLIKQGLSSRKYDDYDCKAADG-------- 126

  Fly   129 SDAMPIVSSITDVFAEELLEKAKKTMDIDLSAKDEILHKKKNRKSIEDEDASANRALDVPAVSEI 193
                      |:...|:|:.......||:.....::...|.:|:.:.|...:..|
plant   127 ----------TNSMNEQLISVTAPIDDIEAPVSPKVEKMKMSRQELIDSPCTRAR---------- 171

  Fly   194 ISTTIGVNRQKDLAELAEIQKKIHAAKKHLRQIGEIGDESDEYDEDLLNLSAREESVDQEPEEDP 258
                   .|:|:....:...:|:      ||.:               .:||.::..|:.|
plant   172 -------RRKKENWNSSGYSRKV------LRSV---------------IVSATQQPCDRNP---- 204

  Fly   259 PKLEAPPRKAKSPIIFNRREKTPEKRP-EAEPEIDSRQEEAEEKSPKK--DSSADKAKEDRSERR 320
                     ||.....|.|.:|.:||| ..|.|:|||...:......:  |:|..:..|...
plant   205 ---------AKYEKSMNERSRTLKKRPYSPERELDSRFAPSGRAVSARYHDASLHQETEPHV--- 257

  Fly   321 SVHDRLGSKAQTPADRSQRNQKELYVPTHRRRSEPEATKERSQRERTRERRSSRDTSRDTNRNQR 385
            ||.||||                        |:..|...:...|..::....:|:|      ...
plant   258 SVWDRLG------------------------RASSECVLDTESRTLSKFGIQTRET------KVH 292

  Fly   386 QRRSPSPEAPSTKQ--RIVSQVIVAVN-KPPEPSDDEDMAEKPVNSVI-KVKPR--PNVSPRRQ- 443
            |:..|...|..::|  .|..:.::||. :...|..|:|  .||.:..| ..:|.  .|:|.:|:
plant   293 QQHGPVFPAAYSEQHSEIFQREVLAVGYRHRVPQFDKD--RKPKSETITSTEPHIAYNLSRKRRY 355

  Fly   444 ----------ACKNLLLRAVADAQRSTILAKTSTQKEDEDVGKIISSLGKRKSED------KNDQ 492
                      :......:|..|.::.::|:..||:   :|:...|.:: |.|.::      ::.|
plant   356 GMVSPNSGEFSYVPQYKQAEQDFEKPSLLSHQSTK---QDIFSEIKNV-KEKMQELELRIIQSKQ 416

  Fly   493 IRKRNRERKRRKRSAQ-GNELFRRTTRE-LVVNVT 525
            ::|:..|  .||.|.| |...::....| .|::||
plant   417 LKKQKVE--ERKPSPQSGESQYQEDVSESRVIHVT 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nab2	NP_651243.1	zf-CCCH_2	878..896	CDD:291282
AT2G24350	NP_180012.2	RRM	347..>525	CDD:223796	24/109 (22%)
AT2G24350	NP_180012.2	RRM_SF	446..517	CDD:302621	2/4 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR14738
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100