DRSC/TRiP Functional Genomics Resources

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Protein Alignment crb and f10

DIOPT Version :10

Sequence 1:NP_001247284.1 Gene:crb / 42896 FlyBaseID:FBgn0259685 Length:2253 Species:Drosophila melanogaster
Sequence 2:NP_001015728.1 Gene:f10 / 548445 XenbaseID:XB-GENE-971433 Length:464 Species:Xenopus tropicalis


Alignment Length:323 Identity:79/323 - (24%)
Similarity:117/323 - (36%) Gaps:90/323 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly  1011 NECDSNPCSKHGNCNDGIGTYTCECEPGFEGTHCE--------INIDECDRYNPCQRGTCYDQID 1067
            ::|.||||...|:|||||..|||.|..||||.:||        :|..|||:|       |.....
 Frog    87 DQCQSNPCQYGGSCNDGINEYTCLCNAGFEGKNCETVKLQLCSLNNGECDQY-------CKAVDR 144

  Fly  1068 DYDCDCDANYGGKNCSVLLKGCDQNPCLNGGACLPYLINEVTHLYNCTCENGFQGDKCEKTTTLS 1132
            |..|.|...|      :|.:        ||.:|||      |..|:|    |.:..|.|:..| .
 Frog   145 DVVCSCTNGY------ILGE--------NGKSCLP------TEKYSC----GRRHMKRERRET-K 184

  Fly  1133 MVATSLISVTTEREEGYDINLQFRTTLPNGVLAFGTTG----EKNEPVSYIL---ELINGRLNLH 1190
            :......:.|..:.|   :.:....|||..    ..||    ..|:|...|:   |...|.....
 Frog   185 LHENDKKNHTDSQNE---VKMNQTGTLPER----NVTGINILNPNDPNVRIVGGRECSQGECPWQ 242

  Fly  1191 SSLLNKWEGVFIGSK-------------LNDSNWHKVFVA-INTS--------HLV--------- 1224
            :.|::..:..|.|..             :|.:.:.||.|. :||.        |.|         
 Frog   243 ALLVSDEDEGFCGGTILSREFILTAAHCMNQTKYFKVVVGELNTKISEGTESIHKVEKIIMHPRF 307

  Fly  1225 LSANDEQAIFPVGSYETANNSQPSFPRTYLGGTIPNLKSYLRHLTHQPSAFVGCMQDIMVNGK 1287
            :.:..:..|..:...|..|     |....:...||:.:...:.|.::|.|.|.....|...|:
 Frog   308 VKSTYDYDIAVIKLKEAIN-----FTENIIPACIPDPEFADQVLMNEPDAMVSGFGRIHERGR 365

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
crbNP_001247284.1 LamG 91..228 CDD:238058
EGF 269..299 CDD:394967
EGF_CA <311..341 CDD:238011
EGF_CA 386..423 CDD:238011
EGF_CA 425..460 CDD:238011
EGF 466..495 CDD:394967
EGF 605..633 CDD:394967
EGF_CA 716..750 CDD:238011
EGF_CA 753..789 CDD:238011
EGF_CA 792..828 CDD:238011
EGF_CA 830..865 CDD:238011
EGF_CA 868..905 CDD:238011
EGF_CA 907..943 CDD:238011
EGF_CA 1009..1045 CDD:238011 19/33 (58%)
EGF_CA 1047..1082 CDD:238011 10/34 (29%)
Laminin_G_1 1155..1290 CDD:395008 33/171 (19%)
EGF 1316..1346 CDD:394967
Laminin_G_1 1388..1550 CDD:395008
EGF_CA <1593..1622 CDD:238011
Laminin_G_2 1692..1828 CDD:460494
EGF_CA 1901..1937 CDD:238011
EGF_CA 1939..1974 CDD:238011
EGF_CA 2057..2094 CDD:238011
EGF_CA 2096..2133 CDD:238011
EGF_CA 2137..2175 CDD:238011
f10NP_001015728.1 GLA 22..84 CDD:214503
EGF_CA 85..121 CDD:238011 19/33 (58%)
FXa_inhibition 128..163 CDD:464251 13/55 (24%)
Tryp_SPc 228..456 CDD:238113 26/143 (18%)
Blue background indicates that the domain is not in the aligned region.

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