DRSC/TRiP Functional Genomics Resources

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Protein Alignment crb and Delta

DIOPT Version :10

Sequence 1:NP_001247284.1 Gene:crb / 42896 FlyBaseID:FBgn0259685 Length:2253 Species:Drosophila melanogaster
Sequence 2:NP_477264.1 Gene:Delta / 42313 FlyBaseID:FBgn0000463 Length:833 Species:Drosophila melanogaster


Alignment Length:545 Identity:158/545 - (28%)
Similarity:221/545 - (40%) Gaps:189/545 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   429 CDKNPCLNGGRCF-----DTYGWYTCQ------CLDGWGGEICDRPMTCQTQQCLNG---GTCLD 479
            ||.|...:|...|     |::|..||.      ||.||.|:.|..|      :|..|   |.| |
  Fly   184 CDLNYYGSGCAKFCRPRDDSFGHSTCSETGEIICLTGWQGDYCHIP------KCAKGCEHGHC-D 241

  Fly   480 KPIGFQCLCPPEYTGELCQIAPSCAQQCPIDSECVGGKCVCKPGSSGPIGHCLPTTTTPTPEQEP 544
            ||  .||:|...:.|.||                  .:||.:|                      
  Fly   242 KP--NQCVCQLGWKGALC------------------NECVLEP---------------------- 264

  Fly   545 TTTPRTTPNPNPAIPNTLTTTTKIPPITTSRTLVGTTTGSRRPPQQPLQSPTQRSASLNACPQEN 609
                                                                            |
  Fly   265 ----------------------------------------------------------------N 265

  Fly   610 CLNGGTCLGYSGNYSCICASGYTGYNCQTSTGDGASALALTPINCNATNGKCLNGGTCSMNGT-- 672
            |:: |||   :..::|||..|:.|..|...            :|....:..|.|||||...|.  
  Fly   266 CIH-GTC---NKPWTCICNEGWGGLYCNQD------------LNYCTNHRPCKNGGTCFNTGEGL 314

  Fly   673 -HCYCAVGYSGDRCEKAENCSPLNCQEPMVCVQNQCLCPENKV--CNQCATQPCQNGGECVDLPN 734
             .|.||.|||||.|                         ||::  |: ....||||||.|:|.|:
  Fly   315 YTCKCAPGYSGDDC-------------------------ENEIYSCD-ADVNPCQNGGTCIDEPH 353

  Fly   735 --GDYECKCTRGWTGRTCGNDVDECTLHPKICGNGICKN------EKG-SYKCYCTPGFTGVHCD 790
              ..|:|.|..||:|:.|...|..|:..|  |..|||:|      .|| .|:|.|..|::|.:||
  Fly   354 TKTGYKCHCANGWSGKMCEEKVLTCSDKP--CHQGICRNVRPGLGSKGQGYQCECPIGYSGPNCD 416

  Fly   791 SDVDECLSFPCLNGATCHNKINAYECVCQPGYEGENCEVDIDECGSNPCSNGSTCIDRINNFTCN 855
            ..:|.|...||:||.:|.   .:.:|:|..|:.|..||.:||:|..:.|.||.||||.:|.:.|.
  Fly   417 LQLDNCSPNPCINGGSCQ---PSGKCICPAGFSGTRCETNIDDCLGHQCENGGTCIDMVNQYRCQ 478

  Fly   856 CIPGMTGRICDIDIDDCVGDPCLNGGQCIDQLGGFRCDCSGTGYEGENCELNIDECLSNPCTNGA 920
            |:||..|..|...:|.|:..||.|||.|::....::|.|. .|:.|::|.::||||.|.||.||.
  Fly   479 CVPGFHGTHCSSKVDLCLIRPCANGGTCLNLNNDYQCTCR-AGFTGKDCSVDIDECSSGPCHNGG 542

  Fly   921 KCLDRVKDYFCDCHNGYKGKNCEQD 945
            .|::||..:.|.|.||::||.|:::
  Fly   543 TCMNRVNSFECVCANGFRGKQCDEE 567

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
crbNP_001247284.1 LamG 91..228 CDD:238058
EGF 269..299 CDD:394967
EGF_CA <311..341 CDD:238011
EGF_CA 386..423 CDD:238011
EGF_CA 425..460 CDD:238011 14/41 (34%)
EGF 466..495 CDD:394967 10/31 (32%)
EGF 605..633 CDD:394967 9/27 (33%)
EGF_CA 716..750 CDD:238011 15/35 (43%)
EGF_CA 753..789 CDD:238011 15/42 (36%)
EGF_CA 792..828 CDD:238011 11/35 (31%)
EGF_CA 830..865 CDD:238011 16/34 (47%)
EGF_CA 868..905 CDD:238011 12/36 (33%)
EGF_CA 907..943 CDD:238011 18/35 (51%)
EGF_CA 1009..1045 CDD:238011
EGF_CA 1047..1082 CDD:238011
Laminin_G_1 1155..1290 CDD:395008
EGF 1316..1346 CDD:394967
Laminin_G_1 1388..1550 CDD:395008
EGF_CA <1593..1622 CDD:238011
Laminin_G_2 1692..1828 CDD:460494
EGF_CA 1901..1937 CDD:238011
EGF_CA 1939..1974 CDD:238011
EGF_CA 2057..2094 CDD:238011
EGF_CA 2096..2133 CDD:238011
EGF_CA 2137..2175 CDD:238011
DeltaNP_477264.1 MNNL 23..182 CDD:462222
DSL 164..226 CDD:128366 14/41 (34%)
EGF_CA 291..329 CDD:238011 17/74 (23%)
EGF_CA 337..372 CDD:238011 15/34 (44%)
EGF_CA 453..488 CDD:238011 16/34 (47%)
EGF_CA 492..526 CDD:238011 12/34 (35%)
EGF_CA 529..564 CDD:238011 18/34 (53%)
Blue background indicates that the domain is not in the aligned region.

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